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Article: Spark plasma sintered hydroxyapatite/graphite nanosheet and hydroxyapatite/multiwalled carbon nanotube composites: Mechanical and in vitro cellular properties

TitleSpark plasma sintered hydroxyapatite/graphite nanosheet and hydroxyapatite/multiwalled carbon nanotube composites: Mechanical and in vitro cellular properties
Authors
KeywordsCarbon-nanotube composites
Cellular properties
Cell culture
Nanocomposites
Spark plasma sintering
Issue Date2011
PublisherWiley - V C H Verlag GmbH & Co KGaA. The Journal's web site is located at http://www.wiley-vch.de/home/aem
Citation
Advanced Engineering Materials, 2011, v. 13 n. 4, p. 336-341 How to Cite?
AbstractHyroxyapatite (HA) and its nanocomposites reinforced with 0.5, 1, 1.5, and 2wt% graphite nanosheets (GNs) and multi-walled carbon nanotubes (MWNTs) are fabricated by means of spark plasma sintering (SPS) process. The effects of MWNT and GN additions on the morphology, mechanical behavior, cell adhesion, and biocompatibility of HA were studied. Three-point-bending test shows that the bending strength of MWNT/HA nanocomposites increases with increasing MWNT content. However, the bending strength of GN/HA nanocomposites initially increases by adding 0.5wt% GN, and then decreases markedly as the filler content increases. Cell culture and viability test results demonstrate that the GNs with diameters of several micrometers retard osteoblast cell adhesion and proliferation on the GN/HA nanocomposite. In contrast, the addition of 2wt% MWNT to HA is beneficial to promote osteoblast adhesion and proliferation, thereby enhancing the biocompatibility of MWNT/HA nanocomposite. Bending test is used to evaluate the bending strength of spark plasma sintered hydroxyapatite (HA)-based composites reinforced with low loading levels of multi-walled carbon nanotubes (MWNTs) and graphite nanosheets (GNs). The bending stress of MWNT/HA nanocomposites increases markedly with increasing filler content. In contrast, the bending stress of GN/HA nanocomposites reaches an apparent maximum at 0.5wt% GN, thereafter decreases continuously with increasing filler content. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA.
Persistent Identifierhttp://hdl.handle.net/10722/139550
ISSN
2014 Impact Factor: 1.758
2014 SCImago Journal Rankings: 0.766
ISI Accession Number ID
Funding AgencyGrant Number
Research Grants Council of Hong Kong, Hong Kong Special Administrative Region, ChinaCityU 120808
Funding Information:

This work is fully supported by the GRF grant (CityU 120808), the Research Grants Council of Hong Kong, Hong Kong Special Administrative Region, China.

References

 

DC FieldValueLanguage
dc.contributor.authorZhu, Jen_HK
dc.contributor.authorWong, HMen_HK
dc.contributor.authorYeung, KWKen_HK
dc.contributor.authorTjong, SCen_HK
dc.date.accessioned2011-09-23T05:51:34Z-
dc.date.available2011-09-23T05:51:34Z-
dc.date.issued2011en_HK
dc.identifier.citationAdvanced Engineering Materials, 2011, v. 13 n. 4, p. 336-341en_HK
dc.identifier.issn1438-1656en_HK
dc.identifier.urihttp://hdl.handle.net/10722/139550-
dc.description.abstractHyroxyapatite (HA) and its nanocomposites reinforced with 0.5, 1, 1.5, and 2wt% graphite nanosheets (GNs) and multi-walled carbon nanotubes (MWNTs) are fabricated by means of spark plasma sintering (SPS) process. The effects of MWNT and GN additions on the morphology, mechanical behavior, cell adhesion, and biocompatibility of HA were studied. Three-point-bending test shows that the bending strength of MWNT/HA nanocomposites increases with increasing MWNT content. However, the bending strength of GN/HA nanocomposites initially increases by adding 0.5wt% GN, and then decreases markedly as the filler content increases. Cell culture and viability test results demonstrate that the GNs with diameters of several micrometers retard osteoblast cell adhesion and proliferation on the GN/HA nanocomposite. In contrast, the addition of 2wt% MWNT to HA is beneficial to promote osteoblast adhesion and proliferation, thereby enhancing the biocompatibility of MWNT/HA nanocomposite. Bending test is used to evaluate the bending strength of spark plasma sintered hydroxyapatite (HA)-based composites reinforced with low loading levels of multi-walled carbon nanotubes (MWNTs) and graphite nanosheets (GNs). The bending stress of MWNT/HA nanocomposites increases markedly with increasing filler content. In contrast, the bending stress of GN/HA nanocomposites reaches an apparent maximum at 0.5wt% GN, thereafter decreases continuously with increasing filler content. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA.en_HK
dc.languageengen_US
dc.publisherWiley - V C H Verlag GmbH & Co KGaA. The Journal's web site is located at http://www.wiley-vch.de/home/aemen_HK
dc.relation.ispartofAdvanced Engineering Materialsen_HK
dc.subjectCarbon-nanotube composites-
dc.subjectCellular properties-
dc.subjectCell culture-
dc.subjectNanocomposites-
dc.subjectSpark plasma sintering-
dc.titleSpark plasma sintered hydroxyapatite/graphite nanosheet and hydroxyapatite/multiwalled carbon nanotube composites: Mechanical and in vitro cellular propertiesen_HK
dc.typeArticleen_HK
dc.identifier.emailYeung, KWK:wkkyeung@hkucc.hku.hken_HK
dc.identifier.authorityYeung, KWK=rp00309en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1002/adem.201000300en_HK
dc.identifier.scopuseid_2-s2.0-79953190060en_HK
dc.identifier.hkuros192183en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-79953190060&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume13en_HK
dc.identifier.issue4en_HK
dc.identifier.spage336en_HK
dc.identifier.epage341en_HK
dc.identifier.isiWOS:000288787500018-
dc.publisher.placeGermanyen_HK
dc.identifier.scopusauthoridZhu, J=36698650500en_HK
dc.identifier.scopusauthoridWong, HM=35977282000en_HK
dc.identifier.scopusauthoridYeung, KWK=13309584700en_HK
dc.identifier.scopusauthoridTjong, SC=7102940723en_HK

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