Article: Spark plasma sintered hydroxyapatite/graphite nanosheet and hydroxyapatite/multiwalled carbon nanotube composites: Mechanical and in vitro cellular properties

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TitleSpark plasma sintered hydroxyapatite/graphite nanosheet and hydroxyapatite/multiwalled carbon nanotube composites: Mechanical and in vitro cellular properties
AuthorsZhu, J2
Wong, HM1
Yeung, KWK1
Tjong, SC2
KeywordsCarbon-nanotube composites
Cellular properties
Cell culture
Nanocomposites
Spark plasma sintering
Issue Date2011
PublisherWiley - V C H Verlag GmbH & Co KGaA. The Journal's web site is located at http://www.wiley-vch.de/home/aem
CitationAdvanced Engineering Materials, 2011, v. 13 n. 4, p. 336-341 [How to Cite?]
DOI: http://dx.doi.org/10.1002/adem.201000300
AbstractHyroxyapatite (HA) and its nanocomposites reinforced with 0.5, 1, 1.5, and 2wt% graphite nanosheets (GNs) and multi-walled carbon nanotubes (MWNTs) are fabricated by means of spark plasma sintering (SPS) process. The effects of MWNT and GN additions on the morphology, mechanical behavior, cell adhesion, and biocompatibility of HA were studied. Three-point-bending test shows that the bending strength of MWNT/HA nanocomposites increases with increasing MWNT content. However, the bending strength of GN/HA nanocomposites initially increases by adding 0.5wt% GN, and then decreases markedly as the filler content increases. Cell culture and viability test results demonstrate that the GNs with diameters of several micrometers retard osteoblast cell adhesion and proliferation on the GN/HA nanocomposite. In contrast, the addition of 2wt% MWNT to HA is beneficial to promote osteoblast adhesion and proliferation, thereby enhancing the biocompatibility of MWNT/HA nanocomposite. Bending test is used to evaluate the bending strength of spark plasma sintered hydroxyapatite (HA)-based composites reinforced with low loading levels of multi-walled carbon nanotubes (MWNTs) and graphite nanosheets (GNs). The bending stress of MWNT/HA nanocomposites increases markedly with increasing filler content. In contrast, the bending stress of GN/HA nanocomposites reaches an apparent maximum at 0.5wt% GN, thereafter decreases continuously with increasing filler content. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA.
ISSN1438-1656
2011 Impact Factor: 1.185
2011 SCImago Journal Rankings: 0.115
DOIhttp://dx.doi.org/10.1002/adem.201000300
ISI Accession Number IDWOS:000288787500018
Funding AgencyGrant Number
Research Grants Council of Hong Kong, Hong Kong Special Administrative Region, ChinaCityU 120808
Funding Information:

This work is fully supported by the GRF grant (CityU 120808), the Research Grants Council of Hong Kong, Hong Kong Special Administrative Region, China.

ReferencesReferences in Scopus
DC Field
Value
dc.contributor.authorZhu, J
dc.contributor.authorWong, HM
dc.contributor.authorYeung, KWK
dc.contributor.authorTjong, SC
dc.date.accessioned2011-09-23T05:51:34Z
dc.date.available2011-09-23T05:51:34Z
dc.date.issued2011
dc.description.abstractHyroxyapatite (HA) and its nanocomposites reinforced with 0.5, 1, 1.5, and 2wt% graphite nanosheets (GNs) and multi-walled carbon nanotubes (MWNTs) are fabricated by means of spark plasma sintering (SPS) process. The effects of MWNT and GN additions on the morphology, mechanical behavior, cell adhesion, and biocompatibility of HA were studied. Three-point-bending test shows that the bending strength of MWNT/HA nanocomposites increases with increasing MWNT content. However, the bending strength of GN/HA nanocomposites initially increases by adding 0.5wt% GN, and then decreases markedly as the filler content increases. Cell culture and viability test results demonstrate that the GNs with diameters of several micrometers retard osteoblast cell adhesion and proliferation on the GN/HA nanocomposite. In contrast, the addition of 2wt% MWNT to HA is beneficial to promote osteoblast adhesion and proliferation, thereby enhancing the biocompatibility of MWNT/HA nanocomposite. Bending test is used to evaluate the bending strength of spark plasma sintered hydroxyapatite (HA)-based composites reinforced with low loading levels of multi-walled carbon nanotubes (MWNTs) and graphite nanosheets (GNs). The bending stress of MWNT/HA nanocomposites increases markedly with increasing filler content. In contrast, the bending stress of GN/HA nanocomposites reaches an apparent maximum at 0.5wt% GN, thereafter decreases continuously with increasing filler content. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA.
dc.description.natureLink_to_subscribed_fulltext
dc.identifier.citationAdvanced Engineering Materials, 2011, v. 13 n. 4, p. 336-341 [How to Cite?]
DOI: http://dx.doi.org/10.1002/adem.201000300
dc.identifier.doihttp://dx.doi.org/10.1002/adem.201000300
dc.identifier.epage341
dc.identifier.hkuros192183
dc.identifier.isiWOS:000288787500018
Funding AgencyGrant Number
Research Grants Council of Hong Kong, Hong Kong Special Administrative Region, ChinaCityU 120808
Funding Information:

This work is fully supported by the GRF grant (CityU 120808), the Research Grants Council of Hong Kong, Hong Kong Special Administrative Region, China.

dc.identifier.issn1438-1656
2011 Impact Factor: 1.185
2011 SCImago Journal Rankings: 0.115
dc.identifier.issue4
dc.identifier.scopuseid_2-s2.0-79953190060
dc.identifier.spage336
dc.identifier.urihttp://hdl.handle.net/10722/139550
dc.identifier.volume13
dc.languageeng
dc.publisherWiley - V C H Verlag GmbH & Co KGaA. The Journal's web site is located at http://www.wiley-vch.de/home/aem
dc.publisher.placeGermany
dc.relation.ispartofAdvanced Engineering Materials
dc.relation.referencesReferences in Scopus
dc.subjectCarbon-nanotube composites
dc.subjectCellular properties
dc.subjectCell culture
dc.subjectNanocomposites
dc.subjectSpark plasma sintering
dc.titleSpark plasma sintered hydroxyapatite/graphite nanosheet and hydroxyapatite/multiwalled carbon nanotube composites: Mechanical and in vitro cellular properties
dc.typeArticle
Author Affiliations
  1. The University of Hong Kong
  2. City University of Hong Kong