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Article: Microfluidic melt emulsification for encapsulation and release of actives

TitleMicrofluidic melt emulsification for encapsulation and release of actives
Authors
Keywordsemulsion
encapsulation
microfluidics
release
Issue Date2010
PublisherAmerican Chemical Society. The Journal's web site is located at http://pubs.acs.org/journal/aamick
Citation
Acs Applied Materials And Interfaces, 2010, v. 2 n. 12, p. 3411-3416 How to Cite?
AbstractA microfluidic melt emulsification method for encapsulation and release of actives is presented. Using a water-in-oil-in-water (W-O-W) double emulsion template, solid capsules can be formed by freezing the middle shell phase. Actives encapsulated inside the solid shell can be controllably and rapidly released by applying a temperature trigger to melt the shell. The choice of the shell materials can be chosen to accommodate the storage and release temperatures specific to the applications. In addition, we have also demonstrated the same concept to encapsulate multiple actives in multicompartment capsules, which are promising as multifunctional capsules and microreactors. © 2010 American Chemical Society.
Persistent Identifierhttp://hdl.handle.net/10722/139369
ISSN
2015 Impact Factor: 7.145
2015 SCImago Journal Rankings: 2.381
ISI Accession Number ID
Funding AgencyGrant Number
BASF
NSFDMR-1006546
Harvard MRSECDMR-0820484
NSFC20676068
China Scholarship Council20083019
Funding Information:

This work was supported by BASF, the NSF (DMR-1006546), the Harvard MRSEC (DMR-0820484), and the NSFC (20676068). B.S. thanks the China Scholarship Council (20083019).

References

 

DC FieldValueLanguage
dc.contributor.authorSun, BJen_HK
dc.contributor.authorShum, HCen_HK
dc.contributor.authorHoltze, Cen_HK
dc.contributor.authorWeitz, DAen_HK
dc.date.accessioned2011-09-23T05:48:55Z-
dc.date.available2011-09-23T05:48:55Z-
dc.date.issued2010en_HK
dc.identifier.citationAcs Applied Materials And Interfaces, 2010, v. 2 n. 12, p. 3411-3416en_HK
dc.identifier.issn1944-8244en_HK
dc.identifier.urihttp://hdl.handle.net/10722/139369-
dc.description.abstractA microfluidic melt emulsification method for encapsulation and release of actives is presented. Using a water-in-oil-in-water (W-O-W) double emulsion template, solid capsules can be formed by freezing the middle shell phase. Actives encapsulated inside the solid shell can be controllably and rapidly released by applying a temperature trigger to melt the shell. The choice of the shell materials can be chosen to accommodate the storage and release temperatures specific to the applications. In addition, we have also demonstrated the same concept to encapsulate multiple actives in multicompartment capsules, which are promising as multifunctional capsules and microreactors. © 2010 American Chemical Society.en_HK
dc.languageengen_US
dc.publisherAmerican Chemical Society. The Journal's web site is located at http://pubs.acs.org/journal/aamicken_HK
dc.relation.ispartofACS Applied Materials and Interfacesen_HK
dc.subjectemulsionen_HK
dc.subjectencapsulationen_HK
dc.subjectmicrofluidicsen_HK
dc.subjectreleaseen_HK
dc.subject.meshCrystallization - methods-
dc.subject.meshDrug Carriers - chemistry-
dc.subject.meshEmulsions - chemistry-
dc.subject.meshMicrofluidics - methods-
dc.subject.meshOils - chemistry-
dc.titleMicrofluidic melt emulsification for encapsulation and release of activesen_HK
dc.typeArticleen_HK
dc.identifier.emailShum, HC:ashum@hku.hken_HK
dc.identifier.authorityShum, HC=rp01439en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1021/am100860ben_HK
dc.identifier.pmid21082834-
dc.identifier.scopuseid_2-s2.0-79151469953en_HK
dc.identifier.hkuros193596en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-79151469953&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume2en_HK
dc.identifier.issue12en_HK
dc.identifier.spage3411en_HK
dc.identifier.epage3416en_HK
dc.identifier.isiWOS:000285449300004-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridSun, BJ=17436079000en_HK
dc.identifier.scopusauthoridShum, HC=23976513800en_HK
dc.identifier.scopusauthoridHoltze, C=9244500700en_HK
dc.identifier.scopusauthoridWeitz, DA=7006798731en_HK

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