Article: Prognostic impact of standardized uptake value of F-18 FDG PET/CT in nasopharyngeal carcinoma
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- Publisher Website: 10.1097/RLU.0b013e31821a29a4
- Scopus: eid_2-s2.0-80053965385
- PMID: 21975389
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| Title | Prognostic impact of standardized uptake value of F-18 FDG PET/CT in nasopharyngeal carcinoma | ||||
|---|---|---|---|---|---|
| Authors | Chan, WKS1 Kwong, DLW1 Yeung, DWC1 Huang, B1 Khong, PL1 | ||||
| Keywords | nasopharyngeal carcinoma PET/CT prognosis survival SUV | ||||
| Issue Date | 2011 | ||||
| Publisher | Lippincott Williams & Wilkins. The Journal's web site is located at http://www.nuclearmed.com/ | ||||
| Citation | Clinical Nuclear Medicine, 2011, v. 36 n. 11, p. 1007-1011 [How to Cite?] DOI: http://dx.doi.org/10.1097/RLU.0b013e31821a29a4 | ||||
| Abstract | Purpose: We evaluated the use of metabolic parameters of F-18 fluorodeoxyglucose positron emission tomography (FDG PET) for the assessment of the primary tumor and nodal metastasis in predicting survival in nasopharyngeal carcinoma (NPC) patients. Materials and Methods: The F-18 FDG PET/CT (computed tomography) scans of 46 consecutive newly diagnosed NPC patients were retrospectively reviewed. Maximal standardized uptake value (SUV max) corrected for lean body mass of primary tumor (pSUV max) and highest SUV max of cervical lymph nodes (nSUV max) were recorded. The association of FDG uptake and 2-year disease-free survival (DFS) was examined. Results: Significantly better DFS was found in patients with pSUV max <7.5 and nSUV max <6.5 (P = 0.042 and P = 0.019, respectively). In multivariate analysis, both pSUV max and nSUV max were significant independent predictors of DFS. Conclusions: The SUV max of the primary tumor and nodal metastasis are useful parameters for predicting DFS in NPC patients. Copyright © 2011 by Lippincott Williams & Wilkins. | ||||
| ISSN | 0363-9762 2011 Impact Factor: 3.674 2011 SCImago Journal Rankings: 0.054 | ||||
| DOI | http://dx.doi.org/10.1097/RLU.0b013e31821a29a4 | ||||
| ISI Accession Number ID | WOS:000295871900015
Funding Information: Conflicts of interest and sources of funding: supported by The Center for Nasopharyngeal Carcinoma Research, Hong Kong SAR, China, AoE grant AoE/M-06/08. | ||||
| References | References in Scopus | ||||
| Grants | Centre for Nasopharyngeal Carcinoma Research |
| dc.contributor.author | Chan, WKS | ||||
|---|---|---|---|---|---|
| dc.contributor.author | Kwong, DLW | ||||
| dc.contributor.author | Yeung, DWC | ||||
| dc.contributor.author | Huang, B | ||||
| dc.contributor.author | Khong, PL | ||||
| dc.date.accessioned | 2011-09-23T05:45:38Z | ||||
| dc.date.available | 2011-09-23T05:45:38Z | ||||
| dc.date.issued | 2011 | ||||
| dc.description.abstract | Purpose: We evaluated the use of metabolic parameters of F-18 fluorodeoxyglucose positron emission tomography (FDG PET) for the assessment of the primary tumor and nodal metastasis in predicting survival in nasopharyngeal carcinoma (NPC) patients. Materials and Methods: The F-18 FDG PET/CT (computed tomography) scans of 46 consecutive newly diagnosed NPC patients were retrospectively reviewed. Maximal standardized uptake value (SUV max) corrected for lean body mass of primary tumor (pSUV max) and highest SUV max of cervical lymph nodes (nSUV max) were recorded. The association of FDG uptake and 2-year disease-free survival (DFS) was examined. Results: Significantly better DFS was found in patients with pSUV max <7.5 and nSUV max <6.5 (P = 0.042 and P = 0.019, respectively). In multivariate analysis, both pSUV max and nSUV max were significant independent predictors of DFS. Conclusions: The SUV max of the primary tumor and nodal metastasis are useful parameters for predicting DFS in NPC patients. Copyright © 2011 by Lippincott Williams & Wilkins. | ||||
| dc.description.grant | Centre for Nasopharyngeal Carcinoma Research | ||||
| dc.description.grantcode | 101179 | ||||
| dc.description.nature | Link_to_subscribed_fulltext | ||||
| dc.identifier.citation | Clinical Nuclear Medicine, 2011, v. 36 n. 11, p. 1007-1011 [How to Cite?] DOI: http://dx.doi.org/10.1097/RLU.0b013e31821a29a4 | ||||
| dc.identifier.doi | http://dx.doi.org/10.1097/RLU.0b013e31821a29a4 | ||||
| dc.identifier.epage | 1011 | ||||
| dc.identifier.hkuros | 192104 | ||||
| dc.identifier.isi | WOS:000295871900015
Funding Information: Conflicts of interest and sources of funding: supported by The Center for Nasopharyngeal Carcinoma Research, Hong Kong SAR, China, AoE grant AoE/M-06/08. | ||||
| dc.identifier.issn | 0363-9762 2011 Impact Factor: 3.674 2011 SCImago Journal Rankings: 0.054 | ||||
| dc.identifier.issue | 11 | ||||
| dc.identifier.openurl | | ||||
| dc.identifier.pmid | 21975389 | ||||
| dc.identifier.scopus | eid_2-s2.0-80053965385 | ||||
| dc.identifier.spage | 1007 | ||||
| dc.identifier.uri | http://hdl.handle.net/10722/139131 | ||||
| dc.identifier.volume | 36 | ||||
| dc.language | eng | ||||
| dc.publisher | Lippincott Williams & Wilkins. The Journal's web site is located at http://www.nuclearmed.com/ | ||||
| dc.publisher.place | United States | ||||
| dc.relation.ispartof | Clinical Nuclear Medicine | ||||
| dc.relation.references | References in Scopus | ||||
| dc.subject | nasopharyngeal carcinoma | ||||
| dc.subject | PET/CT | ||||
| dc.subject | prognosis | ||||
| dc.subject | survival | ||||
| dc.subject | SUV | ||||
| dc.title | Prognostic impact of standardized uptake value of F-18 FDG PET/CT in nasopharyngeal carcinoma | ||||
| dc.type | Article |
Author Affiliations
- The University of Hong Kong