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Article: Dynamic contrast-enhanced MRI of primary rectal cancer: Quantitative correlation with positron emission tomography/computed tomography

TitleDynamic contrast-enhanced MRI of primary rectal cancer: Quantitative correlation with positron emission tomography/computed tomography
Authors
KeywordsDCE-MRI
PET/CT
rectal adenocarcinoma
Issue Date2011
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www.interscience.wiley.com/jpages/1053-1807/
Citation
Journal Of Magnetic Resonance Imaging, 2011, v. 33 n. 2, p. 340-347 How to Cite?
AbstractPurpose To assess the correlations between parameters measured on dynamic contrast-enhanced magnetic resonance imaging and 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) in rectal cancer. Materials and Methods To assess the correlations between parameters measured on dynamic contrast-enhanced MRI and FDG-PET in rectal cancer. Results Significant correlations were only demonstrated between k ep and SUVmax (r = 0.587, P = 0.001), and k ep and SUVmean (r = 0.562, P = 0.002). No significant differences were found in imaging parameters between well, moderately and poorly differentiated adenocarcinoma groups. However, there was a trend that higher imaging values were found in poorly differentiated adenocarcinomas. Conclusion Positive correlations were found between k ep and SUV values in primary rectal adenocarcinomas suggesting an association between angiogenesis and metabolic activity and further reflecting that angiogenic activity in washout phase is better associated with tumor metabolism than the uptake phase. Copyright © 2011 Wiley-Liss, Inc.
Persistent Identifierhttp://hdl.handle.net/10722/139124
ISSN
2014 Impact Factor: 3.210
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorGu, Jen_HK
dc.contributor.authorKhong, PLen_HK
dc.contributor.authorWang, Sen_HK
dc.contributor.authorChan, Qen_HK
dc.contributor.authorWu, EXen_HK
dc.contributor.authorLaw, Wen_HK
dc.contributor.authorLiu, RKen_HK
dc.contributor.authorZhang, Jen_HK
dc.date.accessioned2011-09-23T05:45:31Z-
dc.date.available2011-09-23T05:45:31Z-
dc.date.issued2011en_HK
dc.identifier.citationJournal Of Magnetic Resonance Imaging, 2011, v. 33 n. 2, p. 340-347en_HK
dc.identifier.issn1053-1807en_HK
dc.identifier.urihttp://hdl.handle.net/10722/139124-
dc.description.abstractPurpose To assess the correlations between parameters measured on dynamic contrast-enhanced magnetic resonance imaging and 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) in rectal cancer. Materials and Methods To assess the correlations between parameters measured on dynamic contrast-enhanced MRI and FDG-PET in rectal cancer. Results Significant correlations were only demonstrated between k ep and SUVmax (r = 0.587, P = 0.001), and k ep and SUVmean (r = 0.562, P = 0.002). No significant differences were found in imaging parameters between well, moderately and poorly differentiated adenocarcinoma groups. However, there was a trend that higher imaging values were found in poorly differentiated adenocarcinomas. Conclusion Positive correlations were found between k ep and SUV values in primary rectal adenocarcinomas suggesting an association between angiogenesis and metabolic activity and further reflecting that angiogenic activity in washout phase is better associated with tumor metabolism than the uptake phase. Copyright © 2011 Wiley-Liss, Inc.en_HK
dc.languageengen_US
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www.interscience.wiley.com/jpages/1053-1807/en_HK
dc.relation.ispartofJournal of Magnetic Resonance Imagingen_HK
dc.rightsJournal of Magnetic Resonance Imaging. Copyright © John Wiley & Sons, Inc.-
dc.subjectDCE-MRIen_HK
dc.subjectPET/CTen_HK
dc.subjectrectal adenocarcinomaen_HK
dc.subject.meshAdenocarcinoma - diagnosis-
dc.subject.meshHeterocyclic Compounds - diagnostic use-
dc.subject.meshImage Enhancement - methods-
dc.subject.meshMagnetic Resonance Imaging - methods-
dc.subject.meshOrganometallic Compounds - diagnostic use-
dc.titleDynamic contrast-enhanced MRI of primary rectal cancer: Quantitative correlation with positron emission tomography/computed tomographyen_HK
dc.typeArticleen_HK
dc.identifier.emailKhong, PL: plkhong@hkucc.hku.hken_HK
dc.identifier.emailWu, EX: ewu1@hkucc.hku.hken_HK
dc.identifier.emailLaw, W: lawwl@hkucc.hku.hken_HK
dc.identifier.authorityKhong, PL=rp00467en_HK
dc.identifier.authorityWu, EX=rp00193en_HK
dc.identifier.authorityLaw, W=rp00436en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1002/jmri.22405en_HK
dc.identifier.pmid21274975en_HK
dc.identifier.scopuseid_2-s2.0-79551550812en_HK
dc.identifier.hkuros192031en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-79551550812&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume33en_HK
dc.identifier.issue2en_HK
dc.identifier.spage340en_HK
dc.identifier.epage347en_HK
dc.identifier.isiWOS:000286953300009-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridGu, J=7403129372en_HK
dc.identifier.scopusauthoridKhong, PL=7006693233en_HK
dc.identifier.scopusauthoridWang, S=24598284300en_HK
dc.identifier.scopusauthoridChan, Q=6602497305en_HK
dc.identifier.scopusauthoridWu, EX=7202128034en_HK
dc.identifier.scopusauthoridLaw, W=7103147867en_HK
dc.identifier.scopusauthoridLiu, RK=15056333400en_HK
dc.identifier.scopusauthoridZhang, J=15752209000en_HK

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