Article: Dynamic contrast-enhanced MRI of primary rectal cancer: Quantitative correlation with positron emission tomography/computed tomography

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TitleDynamic contrast-enhanced MRI of primary rectal cancer: Quantitative correlation with positron emission tomography/computed tomography
AuthorsGu, J2
Khong, PL2
Wang, S2
Chan, Q1
Wu, EX2
Law, W2
Liu, RK2
Zhang, J2
KeywordsDCE-MRI
PET/CT
rectal adenocarcinoma
Issue Date2011
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www.interscience.wiley.com/jpages/1053-1807/
CitationJournal Of Magnetic Resonance Imaging, 2011, v. 33 n. 2, p. 340-347 [How to Cite?]
DOI: http://dx.doi.org/10.1002/jmri.22405
AbstractPurpose To assess the correlations between parameters measured on dynamic contrast-enhanced magnetic resonance imaging and 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) in rectal cancer. Materials and Methods To assess the correlations between parameters measured on dynamic contrast-enhanced MRI and FDG-PET in rectal cancer. Results Significant correlations were only demonstrated between k ep and SUVmax (r = 0.587, P = 0.001), and k ep and SUVmean (r = 0.562, P = 0.002). No significant differences were found in imaging parameters between well, moderately and poorly differentiated adenocarcinoma groups. However, there was a trend that higher imaging values were found in poorly differentiated adenocarcinomas. Conclusion Positive correlations were found between k ep and SUV values in primary rectal adenocarcinomas suggesting an association between angiogenesis and metabolic activity and further reflecting that angiogenic activity in washout phase is better associated with tumor metabolism than the uptake phase. Copyright © 2011 Wiley-Liss, Inc.
ISSN1053-1807
2011 Impact Factor: 2.698
2011 SCImago Journal Rankings: 0.242
DOIhttp://dx.doi.org/10.1002/jmri.22405
ISI Accession Number IDWOS:000286953300009
ReferencesReferences in Scopus
DC Field
Value
dc.contributor.authorGu, J
dc.contributor.authorKhong, PL
dc.contributor.authorWang, S
dc.contributor.authorChan, Q
dc.contributor.authorWu, EX
dc.contributor.authorLaw, W
dc.contributor.authorLiu, RK
dc.contributor.authorZhang, J
dc.date.accessioned2011-09-23T05:45:31Z
dc.date.available2011-09-23T05:45:31Z
dc.date.issued2011
dc.description.abstractPurpose To assess the correlations between parameters measured on dynamic contrast-enhanced magnetic resonance imaging and 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) in rectal cancer. Materials and Methods To assess the correlations between parameters measured on dynamic contrast-enhanced MRI and FDG-PET in rectal cancer. Results Significant correlations were only demonstrated between k ep and SUVmax (r = 0.587, P = 0.001), and k ep and SUVmean (r = 0.562, P = 0.002). No significant differences were found in imaging parameters between well, moderately and poorly differentiated adenocarcinoma groups. However, there was a trend that higher imaging values were found in poorly differentiated adenocarcinomas. Conclusion Positive correlations were found between k ep and SUV values in primary rectal adenocarcinomas suggesting an association between angiogenesis and metabolic activity and further reflecting that angiogenic activity in washout phase is better associated with tumor metabolism than the uptake phase. Copyright © 2011 Wiley-Liss, Inc.
dc.description.natureLink_to_subscribed_fulltext
dc.identifier.citationJournal Of Magnetic Resonance Imaging, 2011, v. 33 n. 2, p. 340-347 [How to Cite?]
DOI: http://dx.doi.org/10.1002/jmri.22405
dc.identifier.doihttp://dx.doi.org/10.1002/jmri.22405
dc.identifier.epage347
dc.identifier.hkuros192031
dc.identifier.isiWOS:000286953300009
dc.identifier.issn1053-1807
2011 Impact Factor: 2.698
2011 SCImago Journal Rankings: 0.242
dc.identifier.issue2
dc.identifier.pmid21274975
dc.identifier.scopuseid_2-s2.0-79551550812
dc.identifier.spage340
dc.identifier.urihttp://hdl.handle.net/10722/139124
dc.identifier.volume33
dc.languageeng
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www.interscience.wiley.com/jpages/1053-1807/
dc.publisher.placeUnited States
dc.relation.ispartofJournal of Magnetic Resonance Imaging
dc.relation.referencesReferences in Scopus
dc.rightsJournal of Magnetic Resonance Imaging. Copyright © John Wiley & Sons, Inc.
dc.subject.meshAdenocarcinoma - diagnosis
dc.subject.meshHeterocyclic Compounds - diagnostic use
dc.subject.meshImage Enhancement - methods
dc.subject.meshMagnetic Resonance Imaging - methods
dc.subject.meshOrganometallic Compounds - diagnostic use
dc.subjectDCE-MRI
dc.subjectPET/CT
dc.subjectrectal adenocarcinoma
dc.titleDynamic contrast-enhanced MRI of primary rectal cancer: Quantitative correlation with positron emission tomography/computed tomography
dc.typeArticle
Author Affiliations
  1. Philips Electronics Hong Kong Limited
  2. The University of Hong Kong