File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: The efficacy of oral appliances in the treatment of severe obstructive sleep apnea

TitleThe efficacy of oral appliances in the treatment of severe obstructive sleep apnea
Authors
KeywordsBlood pressure
Oral appliances
Retrognathism
Severe obstructive sleep apnea
Issue Date2011
PublisherSpringer Verlag. The Journal's web site is located at http://www.springer.com/medicine/internal/journal/11325
Citation
Sleep And Breathing, 2011, v. 15 n. 2, p. 195-201 How to Cite?
Abstract
Objectives: The purpose of this study is to evaluate the efficacy of oral appliance (OA) treatment for subjects with severe obstructive sleep apnea (OSA) and to determine the dental parameters associated with treatment outcomes. Study design: This study uses a prospective longitudinal design. Methods: Consecutive Chinese subjects with severe OSA who refused continuous positive airway pressure treatment were recruited. Their dental measurements were taken from lateral cephalometric radiographs. Polysomnograms with OA were repeated at 3 months and 1 year. Blood pressure was taken in the morning after sleep studies. Results: Thirty-four subjects were evaluated at 3 months and 1 year according to the principle of intention-to-treat analysis. OA reduced AHI significantly in subjects with favorable responses, from 49.3 (37.4-67) to 12.5 (6.1-15.7), p<0.001 at 3 months and from 47.5 (41.1-72.9) to 13.1 (6.0-14.0), p<0.001 at 1 year. These OSA subjects had an increased overjet at baseline compared to those with unfavorable responses (p≤0.05). Systolic blood pressure was significantly reduced in those hypertensive OSA subjects after 3 months and 1 year of treatment. Conclusions: OA reduces the severity of sleep apnea, and the effect is maintained at 1 year in subjects with retrognathism. OA appears to reduce systolic blood pressure in hypertensive OSA subjects at 3 months and 1 year. © 2011 Springer-Verlag.
Persistent Identifierhttp://hdl.handle.net/10722/138920
ISSN
2013 Impact Factor: 2.869
ISI Accession Number ID
References

 

Author Affiliations
  1. The University of Hong Kong
DC FieldValueLanguage
dc.contributor.authorLam, Ben_HK
dc.contributor.authorSam, Ken_HK
dc.contributor.authorLam, JCMen_HK
dc.contributor.authorLai, AYKen_HK
dc.contributor.authorLam, CLen_HK
dc.contributor.authorIp, MSMen_HK
dc.date.accessioned2011-09-23T05:41:57Z-
dc.date.available2011-09-23T05:41:57Z-
dc.date.issued2011en_HK
dc.identifier.citationSleep And Breathing, 2011, v. 15 n. 2, p. 195-201en_HK
dc.identifier.issn1520-9512en_HK
dc.identifier.urihttp://hdl.handle.net/10722/138920-
dc.description.abstractObjectives: The purpose of this study is to evaluate the efficacy of oral appliance (OA) treatment for subjects with severe obstructive sleep apnea (OSA) and to determine the dental parameters associated with treatment outcomes. Study design: This study uses a prospective longitudinal design. Methods: Consecutive Chinese subjects with severe OSA who refused continuous positive airway pressure treatment were recruited. Their dental measurements were taken from lateral cephalometric radiographs. Polysomnograms with OA were repeated at 3 months and 1 year. Blood pressure was taken in the morning after sleep studies. Results: Thirty-four subjects were evaluated at 3 months and 1 year according to the principle of intention-to-treat analysis. OA reduced AHI significantly in subjects with favorable responses, from 49.3 (37.4-67) to 12.5 (6.1-15.7), p<0.001 at 3 months and from 47.5 (41.1-72.9) to 13.1 (6.0-14.0), p<0.001 at 1 year. These OSA subjects had an increased overjet at baseline compared to those with unfavorable responses (p≤0.05). Systolic blood pressure was significantly reduced in those hypertensive OSA subjects after 3 months and 1 year of treatment. Conclusions: OA reduces the severity of sleep apnea, and the effect is maintained at 1 year in subjects with retrognathism. OA appears to reduce systolic blood pressure in hypertensive OSA subjects at 3 months and 1 year. © 2011 Springer-Verlag.en_HK
dc.languageengen_US
dc.publisherSpringer Verlag. The Journal's web site is located at http://www.springer.com/medicine/internal/journal/11325 en_HK
dc.relation.ispartofSleep and Breathingen_HK
dc.rightsThe original publication is available at www.springerlink.com-
dc.subjectBlood pressureen_HK
dc.subjectOral appliancesen_HK
dc.subjectRetrognathismen_HK
dc.subjectSevere obstructive sleep apneaen_HK
dc.titleThe efficacy of oral appliances in the treatment of severe obstructive sleep apneaen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1520-9512&volume=15&issue=2&spage=195&epage=201&date=2011&atitle=The+efficacy+of+oral+appliances+in+the+treatment+of+severe+obstructive+sleep+apnea-
dc.identifier.emailLam, CL:lamcl@hkucc.hku.hken_HK
dc.identifier.emailIp, MSM:msmip@hku.hken_HK
dc.identifier.authorityLam, CL=rp01345en_HK
dc.identifier.authorityIp, MSM=rp00347en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1007/s11325-011-0496-yen_HK
dc.identifier.pmid21336702en_HK
dc.identifier.scopuseid_2-s2.0-79958144400en_HK
dc.identifier.hkuros196582en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-79958144400&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume15en_HK
dc.identifier.issue2en_HK
dc.identifier.spage195en_HK
dc.identifier.epage201en_HK
dc.identifier.isiWOS:000290939000007-
dc.publisher.placeGermanyen_HK
dc.identifier.scopusauthoridLam, B=9246012800en_HK
dc.identifier.scopusauthoridSam, K=6603582227en_HK
dc.identifier.scopusauthoridLam, JCM=25923453500en_HK
dc.identifier.scopusauthoridLai, AYK=25641477800en_HK
dc.identifier.scopusauthoridLam, CL=7201749615en_HK
dc.identifier.scopusauthoridIp, MSM=7102423259en_HK
dc.identifier.citeulike8939308-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats