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Article: The efficacy of oral appliances in the treatment of severe obstructive sleep apnea
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TitleThe efficacy of oral appliances in the treatment of severe obstructive sleep apnea
 
AuthorsLam, B1
Sam, K1
Lam, JCM1
Lai, AYK1
Lam, CL1
Ip, MSM1
 
KeywordsBlood pressure
Oral appliances
Retrognathism
Severe obstructive sleep apnea
 
Issue Date2011
 
PublisherSpringer Verlag. The Journal's web site is located at http://www.springer.com/medicine/internal/journal/11325
 
CitationSleep And Breathing, 2011, v. 15 n. 2, p. 195-201 [How to Cite?]
DOI: http://dx.doi.org/10.1007/s11325-011-0496-y
 
AbstractObjectives: The purpose of this study is to evaluate the efficacy of oral appliance (OA) treatment for subjects with severe obstructive sleep apnea (OSA) and to determine the dental parameters associated with treatment outcomes. Study design: This study uses a prospective longitudinal design. Methods: Consecutive Chinese subjects with severe OSA who refused continuous positive airway pressure treatment were recruited. Their dental measurements were taken from lateral cephalometric radiographs. Polysomnograms with OA were repeated at 3 months and 1 year. Blood pressure was taken in the morning after sleep studies. Results: Thirty-four subjects were evaluated at 3 months and 1 year according to the principle of intention-to-treat analysis. OA reduced AHI significantly in subjects with favorable responses, from 49.3 (37.4-67) to 12.5 (6.1-15.7), p<0.001 at 3 months and from 47.5 (41.1-72.9) to 13.1 (6.0-14.0), p<0.001 at 1 year. These OSA subjects had an increased overjet at baseline compared to those with unfavorable responses (p≤0.05). Systolic blood pressure was significantly reduced in those hypertensive OSA subjects after 3 months and 1 year of treatment. Conclusions: OA reduces the severity of sleep apnea, and the effect is maintained at 1 year in subjects with retrognathism. OA appears to reduce systolic blood pressure in hypertensive OSA subjects at 3 months and 1 year. © 2011 Springer-Verlag.
 
ISSN1520-9512
2013 Impact Factor: 2.869
 
DOIhttp://dx.doi.org/10.1007/s11325-011-0496-y
 
ISI Accession Number IDWOS:000290939000007
 
ReferencesReferences in Scopus
 
DC FieldValue
dc.contributor.authorLam, B
 
dc.contributor.authorSam, K
 
dc.contributor.authorLam, JCM
 
dc.contributor.authorLai, AYK
 
dc.contributor.authorLam, CL
 
dc.contributor.authorIp, MSM
 
dc.date.accessioned2011-09-23T05:41:57Z
 
dc.date.available2011-09-23T05:41:57Z
 
dc.date.issued2011
 
dc.description.abstractObjectives: The purpose of this study is to evaluate the efficacy of oral appliance (OA) treatment for subjects with severe obstructive sleep apnea (OSA) and to determine the dental parameters associated with treatment outcomes. Study design: This study uses a prospective longitudinal design. Methods: Consecutive Chinese subjects with severe OSA who refused continuous positive airway pressure treatment were recruited. Their dental measurements were taken from lateral cephalometric radiographs. Polysomnograms with OA were repeated at 3 months and 1 year. Blood pressure was taken in the morning after sleep studies. Results: Thirty-four subjects were evaluated at 3 months and 1 year according to the principle of intention-to-treat analysis. OA reduced AHI significantly in subjects with favorable responses, from 49.3 (37.4-67) to 12.5 (6.1-15.7), p<0.001 at 3 months and from 47.5 (41.1-72.9) to 13.1 (6.0-14.0), p<0.001 at 1 year. These OSA subjects had an increased overjet at baseline compared to those with unfavorable responses (p≤0.05). Systolic blood pressure was significantly reduced in those hypertensive OSA subjects after 3 months and 1 year of treatment. Conclusions: OA reduces the severity of sleep apnea, and the effect is maintained at 1 year in subjects with retrognathism. OA appears to reduce systolic blood pressure in hypertensive OSA subjects at 3 months and 1 year. © 2011 Springer-Verlag.
 
dc.description.natureLink_to_subscribed_fulltext
 
dc.identifier.citationSleep And Breathing, 2011, v. 15 n. 2, p. 195-201 [How to Cite?]
DOI: http://dx.doi.org/10.1007/s11325-011-0496-y
 
dc.identifier.citeulike8939308
 
dc.identifier.doihttp://dx.doi.org/10.1007/s11325-011-0496-y
 
dc.identifier.epage201
 
dc.identifier.hkuros196582
 
dc.identifier.isiWOS:000290939000007
 
dc.identifier.issn1520-9512
2013 Impact Factor: 2.869
 
dc.identifier.issue2
 
dc.identifier.openurl
 
dc.identifier.pmid21336702
 
dc.identifier.scopuseid_2-s2.0-79958144400
 
dc.identifier.spage195
 
dc.identifier.urihttp://hdl.handle.net/10722/138920
 
dc.identifier.volume15
 
dc.languageeng
 
dc.publisherSpringer Verlag. The Journal's web site is located at http://www.springer.com/medicine/internal/journal/11325
 
dc.publisher.placeGermany
 
dc.relation.ispartofSleep and Breathing
 
dc.relation.referencesReferences in Scopus
 
dc.rightsThe original publication is available at www.springerlink.com
 
dc.subjectBlood pressure
 
dc.subjectOral appliances
 
dc.subjectRetrognathism
 
dc.subjectSevere obstructive sleep apnea
 
dc.titleThe efficacy of oral appliances in the treatment of severe obstructive sleep apnea
 
dc.typeArticle
 
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Author Affiliations
  1. The University of Hong Kong