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Article: Perioperative antibiotic prophylaxis in orthognathic surgery: A systematic review and meta-analysis of clinical trials

TitlePerioperative antibiotic prophylaxis in orthognathic surgery: A systematic review and meta-analysis of clinical trials
Authors
Issue Date2011
PublisherMosby, Inc. The Journal's web site is located at http://www.elsevier.com/locate/tripleo
Citation
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology And Endodontology, 2011, v. 112 n. 1, p. 19-27 How to Cite?
AbstractObjective. The aim of this study was to investigate whether the use of antibiotic prophylaxis in orthognathic surgery can effectively reduce the postoperative infection rate. Study design. Electronic databases were searched and reference lists checked. Full articles meeting the inclusion criteria were retrieved. Study details and outcome data of these reports were statistically analyzed. There was no language limitation. Results. Five randomized clinical trials were included in the final review process: 4 articles compared the period of prophylactic antibiotic usage, and 1 compared the infection prevention effect of different types of antibiotics with placebo. Although a significantly higher infection rate was found in the placebo group, no significant difference could be found related to infection prevention between short- and long-term antibiotic regimen. Conclusions. Prophylactic antibiotic regimen is considered to be useful for infection prevention in orthognathic surgery. A single-dose regimen is recommended; application for extended postoperative period is not advocated. © 2011 Mosby, Inc. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/138875
ISSN
2011 Impact Factor: 1.457
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorTan, SKen_HK
dc.contributor.authorLo, Jen_HK
dc.contributor.authorZwahlen, RAen_HK
dc.date.accessioned2011-09-23T05:41:34Z-
dc.date.available2011-09-23T05:41:34Z-
dc.date.issued2011en_HK
dc.identifier.citationOral Surgery, Oral Medicine, Oral Pathology, Oral Radiology And Endodontology, 2011, v. 112 n. 1, p. 19-27en_HK
dc.identifier.issn1079-2104en_HK
dc.identifier.urihttp://hdl.handle.net/10722/138875-
dc.description.abstractObjective. The aim of this study was to investigate whether the use of antibiotic prophylaxis in orthognathic surgery can effectively reduce the postoperative infection rate. Study design. Electronic databases were searched and reference lists checked. Full articles meeting the inclusion criteria were retrieved. Study details and outcome data of these reports were statistically analyzed. There was no language limitation. Results. Five randomized clinical trials were included in the final review process: 4 articles compared the period of prophylactic antibiotic usage, and 1 compared the infection prevention effect of different types of antibiotics with placebo. Although a significantly higher infection rate was found in the placebo group, no significant difference could be found related to infection prevention between short- and long-term antibiotic regimen. Conclusions. Prophylactic antibiotic regimen is considered to be useful for infection prevention in orthognathic surgery. A single-dose regimen is recommended; application for extended postoperative period is not advocated. © 2011 Mosby, Inc. All rights reserved.en_HK
dc.languageengen_US
dc.publisherMosby, Inc. The Journal's web site is located at http://www.elsevier.com/locate/tripleoen_HK
dc.relation.ispartofOral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontologyen_HK
dc.subject.meshAntibiotic Prophylaxis-
dc.subject.meshOrthognathic Surgical Procedures-
dc.subject.meshOsteotomy - classification-
dc.subject.meshRandomized Controlled Trials as Topic-
dc.subject.meshSurgical Wound Infection - prevention and control-
dc.titlePerioperative antibiotic prophylaxis in orthognathic surgery: A systematic review and meta-analysis of clinical trialsen_HK
dc.typeArticleen_HK
dc.identifier.emailLo, J: drjohnlo@hku.hken_HK
dc.identifier.emailZwahlen, RA: zwahlen@hku.hken_HK
dc.identifier.authorityLo, J=rp00041en_HK
dc.identifier.authorityZwahlen, RA=rp00055en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.tripleo.2010.07.015en_HK
dc.identifier.pmid21168350-
dc.identifier.scopuseid_2-s2.0-79958768229en_HK
dc.identifier.hkuros193658en_US
dc.identifier.hkuros193679-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-79958768229&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume112en_HK
dc.identifier.issue1en_HK
dc.identifier.spage19en_HK
dc.identifier.epage27en_HK
dc.identifier.isiWOS:000291480100017-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridTan, SK=54399345000en_HK
dc.identifier.scopusauthoridLo, J=7201650902en_HK
dc.identifier.scopusauthoridZwahlen, RA=7004217269en_HK

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