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Article: The use of lobetyolin and HPLC-UV fingerprints for quality assessment of radix codonopsis

TitleThe use of lobetyolin and HPLC-UV fingerprints for quality assessment of radix codonopsis
Authors
KeywordsFingerprint
HPLC
Lobetyolin
Quantification
Radix codonopsis
Issue Date2007
PublisherBureau of Food and Drug Analysis. The Journal's web site is located at http://www.nlfd.gov.tw/en/jfda/index_E.html
Citation
Journal Of Food And Drug Analysis, 2007, v. 15 n. 3, p. 258-264 How to Cite?
AbstractIn 2005 edition of the Chinese Pharmacopoeia, lobetyolin was used as a marker for TLC identification of Radix Codonopsis, whose source plants are Codonopsis pilosula, C. pilosula var. modesta and C. tangshen. Quantification of lobetyolin in 44 samples derived from eight species of Codonopsis and another four genera of the same family Campanulaceae revealed that lobetyolin is present in all Codonopsis species and in Campanumoea javanica, Platycodon grandiflorum and Lobelia chinensis. In fact, the other five Codonopsis species are commonly used as the substitutes of Radix Codonopsis, and the roots of Campanumoea javanica and Platycodon grandiflorum are sometimes found as the adulterants. Contents of lobetyolin were found variable among different samples, and some substitutes and adulterants actually had comparably high contents of lobetyolin. Therefore, lobetyolin should be taken only as a general but not a definitive marker for the identification of Radix Codonopsis. HPLC-UV fingerprints with seven characteristic peaks were established for discriminating Radix Codonopsis from its adulterants, but more specific and definitive markers remain to be identified for differentiating Radix Codonopsis from its substitutes.
Persistent Identifierhttp://hdl.handle.net/10722/138119
ISSN
2015 Impact Factor: 1.98
2015 SCImago Journal Rankings: 0.510
References

 

DC FieldValueLanguage
dc.contributor.authorQiao, CFen_HK
dc.contributor.authorHe, ZDen_HK
dc.contributor.authorHan, QBen_HK
dc.contributor.authorXu, HXen_HK
dc.contributor.authorJiang, RWen_HK
dc.contributor.authorLi, SLen_HK
dc.contributor.authorZhang, YBen_HK
dc.contributor.authorBut, PPHen_HK
dc.contributor.authorShaw, PCen_HK
dc.date.accessioned2011-08-26T14:41:02Z-
dc.date.available2011-08-26T14:41:02Z-
dc.date.issued2007en_HK
dc.identifier.citationJournal Of Food And Drug Analysis, 2007, v. 15 n. 3, p. 258-264en_HK
dc.identifier.issn1021-9498en_HK
dc.identifier.urihttp://hdl.handle.net/10722/138119-
dc.description.abstractIn 2005 edition of the Chinese Pharmacopoeia, lobetyolin was used as a marker for TLC identification of Radix Codonopsis, whose source plants are Codonopsis pilosula, C. pilosula var. modesta and C. tangshen. Quantification of lobetyolin in 44 samples derived from eight species of Codonopsis and another four genera of the same family Campanulaceae revealed that lobetyolin is present in all Codonopsis species and in Campanumoea javanica, Platycodon grandiflorum and Lobelia chinensis. In fact, the other five Codonopsis species are commonly used as the substitutes of Radix Codonopsis, and the roots of Campanumoea javanica and Platycodon grandiflorum are sometimes found as the adulterants. Contents of lobetyolin were found variable among different samples, and some substitutes and adulterants actually had comparably high contents of lobetyolin. Therefore, lobetyolin should be taken only as a general but not a definitive marker for the identification of Radix Codonopsis. HPLC-UV fingerprints with seven characteristic peaks were established for discriminating Radix Codonopsis from its adulterants, but more specific and definitive markers remain to be identified for differentiating Radix Codonopsis from its substitutes.en_HK
dc.languageengen_US
dc.publisherBureau of Food and Drug Analysis. The Journal's web site is located at http://www.nlfd.gov.tw/en/jfda/index_E.htmlen_HK
dc.relation.ispartofJournal of Food and Drug Analysisen_HK
dc.subjectFingerprinten_HK
dc.subjectHPLCen_HK
dc.subjectLobetyolinen_HK
dc.subjectQuantificationen_HK
dc.subjectRadix codonopsisen_HK
dc.titleThe use of lobetyolin and HPLC-UV fingerprints for quality assessment of radix codonopsisen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1021-9498&volume=15&issue=3&spage=258&epage=264&date=2007&atitle=The+use+of+lobetyolin+and+HPLC-UV+fingerprints+for+quality+assessment+of+radix+codonopsisen_US
dc.identifier.emailZhang, YB: ybzhang@hku.hken_HK
dc.identifier.authorityZhang, YB=rp01410en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.scopuseid_2-s2.0-36448977274en_HK
dc.identifier.hkuros158756en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-36448977274&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume15en_HK
dc.identifier.issue3en_HK
dc.identifier.spage258en_HK
dc.identifier.epage264en_HK
dc.publisher.placeTaiwan, Republic of Chinaen_HK
dc.identifier.scopusauthoridQiao, CF=9746680900en_HK
dc.identifier.scopusauthoridHe, ZD=7403885660en_HK
dc.identifier.scopusauthoridHan, QB=7202485341en_HK
dc.identifier.scopusauthoridXu, HX=7407449416en_HK
dc.identifier.scopusauthoridJiang, RW=7202306833en_HK
dc.identifier.scopusauthoridLi, SL=36071713200en_HK
dc.identifier.scopusauthoridZhang, YB=23483121900en_HK
dc.identifier.scopusauthoridBut, PPH=7005593430en_HK
dc.identifier.scopusauthoridShaw, PC=35599523600en_HK

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