Conference Paper: Anti-tumor efficacy of a recombinant human arginase in combination with chemotherapeutic agents in human hepatocellular carcinoma
| Title | Anti-tumor efficacy of a recombinant human arginase in combination with chemotherapeutic agents in human hepatocellular carcinoma |
|---|---|
| Authors | Chow, A Pang, R Chu, A Ng, L Poon, R |
| Keywords | Medical sciences Oncology |
| Issue Date | 2011 |
| Publisher | American Association for Cancer Research. The Journal's web site is located at http://cancerres.aacrjournals.org/ |
| Citation | The 102nd Annual Meeting of the American Association for Cancer Research (AACR 2011), Orlando, FL., 2-6 April 2011. In Cancer Research, 2011, v. 71 n. 8, suppl. 1, abstract no. 5382 [How to Cite?] DOI: http://dx.doi.org/10.1158/1538-7445.AM2011-5382 |
| Abstract | INTRODUCTION: Systemic chemotherapy of hepatocellular carcinoma (HCC) relies on few drugs and the response rates are low especially in patients with advanced HCC. HCC is considered as auxotrophic for arginine due to the lack of expression of argininosuccinate synthetase (ASS). Several recombinant human arginases were found to be effective in inhibiting liver, pancreatic and leukemic cell proliferation. Recently ... |
| Description | This journal suppl. is conference proceedings of AACR 2011 Poster Presentations - Enhancing Efficacy of Targeted Agents: abstract no. 5382 |
| ISSN | 0008-5472 2011 Impact Factor: 7.856 2011 SCImago Journal Rankings: 1.309 |
| DOI | http://dx.doi.org/10.1158/1538-7445.AM2011-5382 |
| dc.contributor.author | Chow, A |
|---|---|
| dc.contributor.author | Pang, R |
| dc.contributor.author | Chu, A |
| dc.contributor.author | Ng, L |
| dc.contributor.author | Poon, R |
| dc.date.accessioned | 2011-08-26T14:36:59Z |
| dc.date.available | 2011-08-26T14:36:59Z |
| dc.date.issued | 2011 |
| dc.description.abstract | INTRODUCTION: Systemic chemotherapy of hepatocellular carcinoma (HCC) relies on few drugs and the response rates are low especially in patients with advanced HCC. HCC is considered as auxotrophic for arginine due to the lack of expression of argininosuccinate synthetase (ASS). Several recombinant human arginases were found to be effective in inhibiting liver, pancreatic and leukemic cell proliferation. Recently ... |
| dc.description.nature | link_to_OA_fulltext |
| dc.description | This journal suppl. is conference proceedings of AACR 2011 |
| dc.description | Poster Presentations - Enhancing Efficacy of Targeted Agents: abstract no. 5382 |
| dc.description.other | The 102nd Annual Meeting of the American Association for Cancer Research (AACR 2011), Orlando, FL., 2-6 April 2011. In Cancer Research, 2011, v. 71 n. 8, suppl. 1, abstract no. 5382 |
| dc.identifier.citation | The 102nd Annual Meeting of the American Association for Cancer Research (AACR 2011), Orlando, FL., 2-6 April 2011. In Cancer Research, 2011, v. 71 n. 8, suppl. 1, abstract no. 5382 [How to Cite?] DOI: http://dx.doi.org/10.1158/1538-7445.AM2011-5382 |
| dc.identifier.doi | http://dx.doi.org/10.1158/1538-7445.AM2011-5382 |
| dc.identifier.hkuros | 191920 |
| dc.identifier.issn | 0008-5472 2011 Impact Factor: 7.856 2011 SCImago Journal Rankings: 1.309 |
| dc.identifier.issue | 8, suppl. 1 |
| dc.identifier.uri | http://hdl.handle.net/10722/137925 |
| dc.identifier.volume | 71 |
| dc.language | eng |
| dc.publisher | American Association for Cancer Research. The Journal's web site is located at http://cancerres.aacrjournals.org/ |
| dc.publisher.place | United States |
| dc.relation.ispartof | Cancer Research |
| dc.subject | Medical sciences |
| dc.subject | Oncology |
| dc.title | Anti-tumor efficacy of a recombinant human arginase in combination with chemotherapeutic agents in human hepatocellular carcinoma |
| dc.type | Conference_Paper |