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Conference Paper: Anti-tumor efficacy of a recombinant human arginase in combination with chemotherapeutic agents in human hepatocellular carcinoma
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TitleAnti-tumor efficacy of a recombinant human arginase in combination with chemotherapeutic agents in human hepatocellular carcinoma
 
AuthorsChow, A
Pang, R
Chu, A
Ng, L
Poon, R
 
KeywordsMedical sciences
Oncology
 
Issue Date2011
 
PublisherAmerican Association for Cancer Research. The Journal's web site is located at http://cancerres.aacrjournals.org/
 
CitationThe 102nd Annual Meeting of the American Association for Cancer Research (AACR 2011), Orlando, FL., 2-6 April 2011. In Cancer Research, 2011, v. 71 n. 8, suppl. 1, abstract no. 5382 [How to Cite?]
DOI: http://dx.doi.org/10.1158/1538-7445.AM2011-5382
 
AbstractINTRODUCTION: Systemic chemotherapy of hepatocellular carcinoma (HCC) relies on few drugs and the response rates are low especially in patients with advanced HCC. HCC is considered as auxotrophic for arginine due to the lack of expression of argininosuccinate synthetase (ASS). Several recombinant human arginases were found to be effective in inhibiting liver, pancreatic and leukemic cell proliferation. Recently ...
 
DescriptionThis journal suppl. is conference proceedings of AACR 2011
Poster Presentations - Enhancing Efficacy of Targeted Agents: abstract no. 5382
 
ISSN0008-5472
2013 Impact Factor: 9.284
2013 SCImago Journal Rankings: 5.627
 
DOIhttp://dx.doi.org/10.1158/1538-7445.AM2011-5382
 
DC FieldValue
dc.contributor.authorChow, A
 
dc.contributor.authorPang, R
 
dc.contributor.authorChu, A
 
dc.contributor.authorNg, L
 
dc.contributor.authorPoon, R
 
dc.date.accessioned2011-08-26T14:36:59Z
 
dc.date.available2011-08-26T14:36:59Z
 
dc.date.issued2011
 
dc.description.abstractINTRODUCTION: Systemic chemotherapy of hepatocellular carcinoma (HCC) relies on few drugs and the response rates are low especially in patients with advanced HCC. HCC is considered as auxotrophic for arginine due to the lack of expression of argininosuccinate synthetase (ASS). Several recombinant human arginases were found to be effective in inhibiting liver, pancreatic and leukemic cell proliferation. Recently ...
 
dc.description.naturelink_to_OA_fulltext
 
dc.descriptionThis journal suppl. is conference proceedings of AACR 2011
 
dc.descriptionPoster Presentations - Enhancing Efficacy of Targeted Agents: abstract no. 5382
 
dc.description.otherThe 102nd Annual Meeting of the American Association for Cancer Research (AACR 2011), Orlando, FL., 2-6 April 2011. In Cancer Research, 2011, v. 71 n. 8, suppl. 1, abstract no. 5382
 
dc.identifier.citationThe 102nd Annual Meeting of the American Association for Cancer Research (AACR 2011), Orlando, FL., 2-6 April 2011. In Cancer Research, 2011, v. 71 n. 8, suppl. 1, abstract no. 5382 [How to Cite?]
DOI: http://dx.doi.org/10.1158/1538-7445.AM2011-5382
 
dc.identifier.doihttp://dx.doi.org/10.1158/1538-7445.AM2011-5382
 
dc.identifier.hkuros191920
 
dc.identifier.issn0008-5472
2013 Impact Factor: 9.284
2013 SCImago Journal Rankings: 5.627
 
dc.identifier.issue8, suppl. 1
 
dc.identifier.urihttp://hdl.handle.net/10722/137925
 
dc.identifier.volume71
 
dc.languageeng
 
dc.publisherAmerican Association for Cancer Research. The Journal's web site is located at http://cancerres.aacrjournals.org/
 
dc.publisher.placeUnited States
 
dc.relation.ispartofCancer Research
 
dc.subjectMedical sciences
 
dc.subjectOncology
 
dc.titleAnti-tumor efficacy of a recombinant human arginase in combination with chemotherapeutic agents in human hepatocellular carcinoma
 
dc.typeConference_Paper
 
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