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Article: Post-hepatectomy haemorrhage: A definition and grading by the International Study Group of Liver Surgery (ISGLS)

TitlePost-hepatectomy haemorrhage: A definition and grading by the International Study Group of Liver Surgery (ISGLS)
Authors
Keywordscomplication
Haemorrhage
Hepatectomy
Liver
Resection
transfusion
Issue Date2011
PublisherWiley-Blackwell Publishing Ltd. The Journal's web site is located at http://www.wiley.com/WileyCDA/WileyTitle/productCd-HPB.html
Citation
Hpb, 2011, v. 13 n. 8, p. 528-535 How to Cite?
AbstractBackground: A standardized definition of post-hepatectomy haemorrhage (PHH) has not yet been established. Methods: An international study group of hepatobiliary surgeons from high-volume centres was convened and a definition of PHH was developed together with a grading of severity considering the impact on patients' clinical management. Results: The definition of PHH varies strongly within the hepatic surgery literature. PHH is defined as a drop in haemoglobin level >3 g/dl post-operatively compared with the post-operative baseline level and/or any post-operative transfusion of packed red blood cells (PRBC) for a falling haemoglobin and/or the need for radiological intervention (such as embolization) and/or re-laparotomy to stop bleeding. Evidence of intra-abdominal bleeding should be obtained by imaging or blood loss via the abdominal drains if present. Transfusion of up to two units of PRBC is considered as being Grade A PHH. Grade B PHH requires transfusion of more than two units of PRBC, whereas the need for invasive re-intervention such as embolization and/ or re-laparotomy defines Grade C PHH. Conclusion: The proposed definition and grading of severity of PHH enables valid comparisons of results from different studies. It is easily applicable in clinical routine and should be applied in future trials to standardize reporting of complications. © 2011 International Hepato-Pancreato-Biliary Association.
Persistent Identifierhttp://hdl.handle.net/10722/137556
ISSN
2015 Impact Factor: 2.918
2015 SCImago Journal Rankings: 1.586
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorRahbari, NNen_HK
dc.contributor.authorGarden, OJen_HK
dc.contributor.authorPadbury, Ren_HK
dc.contributor.authorMaddern, Gen_HK
dc.contributor.authorKoch, Men_HK
dc.contributor.authorHugh, TJen_HK
dc.contributor.authorFan, STen_HK
dc.contributor.authorNimura, Yen_HK
dc.contributor.authorFigueras, Jen_HK
dc.contributor.authorVauthey, JNen_HK
dc.contributor.authorRees, Men_HK
dc.contributor.authorAdam, Ren_HK
dc.contributor.authorDematteo, RPen_HK
dc.contributor.authorGreig, Pen_HK
dc.contributor.authorUsatoff, Ven_HK
dc.contributor.authorBanting, Sen_HK
dc.contributor.authorNagino, Men_HK
dc.contributor.authorCapussotti, Len_HK
dc.contributor.authorYokoyama, Yen_HK
dc.contributor.authorBrookeSmith, Men_HK
dc.contributor.authorCrawford, Men_HK
dc.contributor.authorChristophi, Cen_HK
dc.contributor.authorMakuuchi, Men_HK
dc.contributor.authorBüchler, MWen_HK
dc.contributor.authorWeitz, Jen_HK
dc.date.accessioned2011-08-26T14:27:55Z-
dc.date.available2011-08-26T14:27:55Z-
dc.date.issued2011en_HK
dc.identifier.citationHpb, 2011, v. 13 n. 8, p. 528-535en_HK
dc.identifier.issn1365-182Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/137556-
dc.description.abstractBackground: A standardized definition of post-hepatectomy haemorrhage (PHH) has not yet been established. Methods: An international study group of hepatobiliary surgeons from high-volume centres was convened and a definition of PHH was developed together with a grading of severity considering the impact on patients' clinical management. Results: The definition of PHH varies strongly within the hepatic surgery literature. PHH is defined as a drop in haemoglobin level >3 g/dl post-operatively compared with the post-operative baseline level and/or any post-operative transfusion of packed red blood cells (PRBC) for a falling haemoglobin and/or the need for radiological intervention (such as embolization) and/or re-laparotomy to stop bleeding. Evidence of intra-abdominal bleeding should be obtained by imaging or blood loss via the abdominal drains if present. Transfusion of up to two units of PRBC is considered as being Grade A PHH. Grade B PHH requires transfusion of more than two units of PRBC, whereas the need for invasive re-intervention such as embolization and/ or re-laparotomy defines Grade C PHH. Conclusion: The proposed definition and grading of severity of PHH enables valid comparisons of results from different studies. It is easily applicable in clinical routine and should be applied in future trials to standardize reporting of complications. © 2011 International Hepato-Pancreato-Biliary Association.en_HK
dc.languageengen_US
dc.publisherWiley-Blackwell Publishing Ltd. The Journal's web site is located at http://www.wiley.com/WileyCDA/WileyTitle/productCd-HPB.htmlen_HK
dc.relation.ispartofHPBen_HK
dc.subjectcomplicationen_HK
dc.subjectHaemorrhageen_HK
dc.subjectHepatectomyen_HK
dc.subjectLiveren_HK
dc.subjectResectionen_HK
dc.subjecttransfusionen_HK
dc.titlePost-hepatectomy haemorrhage: A definition and grading by the International Study Group of Liver Surgery (ISGLS)en_HK
dc.typeArticleen_HK
dc.identifier.emailFan, ST: stfan@hku.hken_HK
dc.identifier.authorityFan, ST=rp00355en_HK
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1111/j.1477-2574.2011.00319.xen_HK
dc.identifier.pmid21762295-
dc.identifier.scopuseid_2-s2.0-79960563603en_HK
dc.identifier.hkuros191299en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-79960563603&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume13en_HK
dc.identifier.issue8en_HK
dc.identifier.spage528en_HK
dc.identifier.epage535en_HK
dc.identifier.isiWOS:000292862600002-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridRahbari, NN=21834967000en_HK
dc.identifier.scopusauthoridGarden, OJ=7006432342en_HK
dc.identifier.scopusauthoridPadbury, R=6603924012en_HK
dc.identifier.scopusauthoridMaddern, G=26643080100en_HK
dc.identifier.scopusauthoridKoch, M=7401817256en_HK
dc.identifier.scopusauthoridHugh, TJ=7005891942en_HK
dc.identifier.scopusauthoridFan, ST=7402678224en_HK
dc.identifier.scopusauthoridNimura, Y=7201351672en_HK
dc.identifier.scopusauthoridFigueras, J=7101801203en_HK
dc.identifier.scopusauthoridVauthey, JN=35270590000en_HK
dc.identifier.scopusauthoridRees, M=7201512301en_HK
dc.identifier.scopusauthoridAdam, R=7202478918en_HK
dc.identifier.scopusauthoridDematteo, RP=7006076369en_HK
dc.identifier.scopusauthoridGreig, P=7006982425en_HK
dc.identifier.scopusauthoridUsatoff, V=36731616800en_HK
dc.identifier.scopusauthoridBanting, S=6602131475en_HK
dc.identifier.scopusauthoridNagino, M=7006620971en_HK
dc.identifier.scopusauthoridCapussotti, L=7004492027en_HK
dc.identifier.scopusauthoridYokoyama, Y=7402993620en_HK
dc.identifier.scopusauthoridBrookeSmith, M=6505945819en_HK
dc.identifier.scopusauthoridCrawford, M=7402706739en_HK
dc.identifier.scopusauthoridChristophi, C=7003908136en_HK
dc.identifier.scopusauthoridMakuuchi, M=36050194500en_HK
dc.identifier.scopusauthoridBüchler, MW=35277875400en_HK
dc.identifier.scopusauthoridWeitz, J=7102347790en_HK

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