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Article: Nasopharyngectomy for locally advanced recurrent nasopharyngeal carcinoma: Exploring the limits

TitleNasopharyngectomy for locally advanced recurrent nasopharyngeal carcinoma: Exploring the limits
Authors
KeywordsCraniofacial resection
Maxillary swing operation
Recurrent nasopharyngeal carcinoma
Vastus lateralis muscle flap
Issue Date2012
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/38137
Citation
Head And Neck, 2012, v. 34 n. 7, p. 923-928 How to Cite?
AbstractBackground. The purpose of this study was to present the outcome of nasopharyngectomy for locally advanced recurrent nasopharyngeal carcinoma (NPC). Methods. Between 2000 and 2010, patients with locally advanced recurrent NPC were recruited. Surgical outcomes were analyzed retrospectively. Results. Among the 22 patients recruited, all had extended resections via the maxillary swing approach, resulting in exposure of the petrosal part of the internal carotid artery (ICA). One patient required craniofacial approach for tumor removal. The curative resection rate was 81.8%. Free flap reconstruction was performed in all cases. The mean follow-up period was 38.8 months. All patients survived. Although 1 patient developed local and systemic tumor recurrence, the rest of the patients remained disease free. There was no carotid blowout or osteoradionecrosis of the skull base. Conclusion. Curative resections can be achieved for locally advanced recurrent NPC with good outcome. Microvascular free flap reconstruction is crucial to prevent carotid artery blowout and osteoradionecrosis of the skull base. © 2011 Wiley Periodicals, Inc.
Persistent Identifierhttp://hdl.handle.net/10722/137553
ISSN
2015 Impact Factor: 2.76
2015 SCImago Journal Rankings: 1.233
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorChan, JYWen_HK
dc.contributor.authorChow, VLYen_HK
dc.contributor.authorTsang, Ren_HK
dc.contributor.authorWei, WIen_HK
dc.date.accessioned2011-08-26T14:27:52Z-
dc.date.available2011-08-26T14:27:52Z-
dc.date.issued2012en_HK
dc.identifier.citationHead And Neck, 2012, v. 34 n. 7, p. 923-928en_HK
dc.identifier.issn1043-3074en_HK
dc.identifier.urihttp://hdl.handle.net/10722/137553-
dc.description.abstractBackground. The purpose of this study was to present the outcome of nasopharyngectomy for locally advanced recurrent nasopharyngeal carcinoma (NPC). Methods. Between 2000 and 2010, patients with locally advanced recurrent NPC were recruited. Surgical outcomes were analyzed retrospectively. Results. Among the 22 patients recruited, all had extended resections via the maxillary swing approach, resulting in exposure of the petrosal part of the internal carotid artery (ICA). One patient required craniofacial approach for tumor removal. The curative resection rate was 81.8%. Free flap reconstruction was performed in all cases. The mean follow-up period was 38.8 months. All patients survived. Although 1 patient developed local and systemic tumor recurrence, the rest of the patients remained disease free. There was no carotid blowout or osteoradionecrosis of the skull base. Conclusion. Curative resections can be achieved for locally advanced recurrent NPC with good outcome. Microvascular free flap reconstruction is crucial to prevent carotid artery blowout and osteoradionecrosis of the skull base. © 2011 Wiley Periodicals, Inc.en_HK
dc.languageengen_US
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/38137en_HK
dc.relation.ispartofHead and Necken_HK
dc.rightsHead & Neck: journal for the sciences and specialities of the head and neck. Copyright © John Wiley & Sons, Inc.-
dc.subjectCraniofacial resectionen_HK
dc.subjectMaxillary swing operationen_HK
dc.subjectRecurrent nasopharyngeal carcinomaen_HK
dc.subjectVastus lateralis muscle flapen_HK
dc.titleNasopharyngectomy for locally advanced recurrent nasopharyngeal carcinoma: Exploring the limitsen_HK
dc.typeArticleen_HK
dc.identifier.emailChan, JYW: jywchan1@hku.hken_HK
dc.identifier.emailTsang, R: rkytsang@hku.hken_HK
dc.identifier.emailWei, WI: hrmswwi@hku.hken_HK
dc.identifier.authorityChan, JYW=rp01314en_HK
dc.identifier.authorityTsang, R=rp01386en_HK
dc.identifier.authorityWei, WI=rp00323en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1002/hed.21855en_HK
dc.identifier.pmid21818821-
dc.identifier.scopuseid_2-s2.0-84862860980en_HK
dc.identifier.hkuros190791en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-84862860980&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume34en_HK
dc.identifier.issue7en_HK
dc.identifier.spage923en_HK
dc.identifier.epage928en_HK
dc.identifier.isiWOS:000305513100002-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridChan, JYW=27171772200en_HK
dc.identifier.scopusauthoridChow, VLY=36807611300en_HK
dc.identifier.scopusauthoridTsang, R=7102940058en_HK
dc.identifier.scopusauthoridWei, WI=7403321552en_HK

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