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Article: Efficacy of neck dissection for locoregional failures versus isolated nodal failures in nasopharyngeal carcinoma

TitleEfficacy of neck dissection for locoregional failures versus isolated nodal failures in nasopharyngeal carcinoma
Authors
Keywordslocoregional recurrence
nasopharyngeal carcinoma
neck dissection
nodal recurrence
salvage surgery
Issue Date2012
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/38137
Citation
Head And Neck, 2012, v. 34 n. 5, p. 638-642 How to Cite?
AbstractBackground Neck dissection has been shown to be effective in controlling nodal failures in nasopharyngeal carcinoma. Its efficacy in controlling the disease in patients with synchronous locoregional failure is, however, not documented. Method A retrospective review of all patients who underwent neck dissection for nodal failures with or without treated local failure within 6 months was conducted for this study. The survivals of these 2 groups of patients were analyzed. Results The 5-year overall survival of the whole cohort was 58%. There was no difference in 5-year disease specific survival (68% vs 40%; p =.121) and 5-year progression free survival (44% vs 36%; p =.334) when comparing patients with isolated nodal failures and synchronous locoregional failures. Multivariate analysis showed that only the initial N classification affects survival. Conclusion Neck dissection is efficacious in patients with nasopharyngeal carcinoma with nodal failure, with or without synchronous local failures. © 2011 Wiley Periodicals, Inc.
Persistent Identifierhttp://hdl.handle.net/10722/137548
ISSN
2015 Impact Factor: 2.76
2015 SCImago Journal Rankings: 1.233
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorTsang, RKYen_HK
dc.contributor.authorChung, JCKen_HK
dc.contributor.authorNg, YWen_HK
dc.contributor.authorTo, VSHen_HK
dc.contributor.authorHo, ACWen_HK
dc.contributor.authorChan, JYWen_HK
dc.contributor.authorHo, WKen_HK
dc.contributor.authorWei, WIen_HK
dc.date.accessioned2011-08-26T14:27:50Z-
dc.date.available2011-08-26T14:27:50Z-
dc.date.issued2012en_HK
dc.identifier.citationHead And Neck, 2012, v. 34 n. 5, p. 638-642en_HK
dc.identifier.issn1043-3074en_HK
dc.identifier.urihttp://hdl.handle.net/10722/137548-
dc.description.abstractBackground Neck dissection has been shown to be effective in controlling nodal failures in nasopharyngeal carcinoma. Its efficacy in controlling the disease in patients with synchronous locoregional failure is, however, not documented. Method A retrospective review of all patients who underwent neck dissection for nodal failures with or without treated local failure within 6 months was conducted for this study. The survivals of these 2 groups of patients were analyzed. Results The 5-year overall survival of the whole cohort was 58%. There was no difference in 5-year disease specific survival (68% vs 40%; p =.121) and 5-year progression free survival (44% vs 36%; p =.334) when comparing patients with isolated nodal failures and synchronous locoregional failures. Multivariate analysis showed that only the initial N classification affects survival. Conclusion Neck dissection is efficacious in patients with nasopharyngeal carcinoma with nodal failure, with or without synchronous local failures. © 2011 Wiley Periodicals, Inc.en_HK
dc.languageengen_US
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/38137en_HK
dc.relation.ispartofHead and Necken_HK
dc.rightsHead & Neck: journal for the sciences and specialities of the head and neck. Copyright © John Wiley & Sons, Inc.-
dc.subjectlocoregional recurrenceen_HK
dc.subjectnasopharyngeal carcinomaen_HK
dc.subjectneck dissectionen_HK
dc.subjectnodal recurrenceen_HK
dc.subjectsalvage surgeryen_HK
dc.titleEfficacy of neck dissection for locoregional failures versus isolated nodal failures in nasopharyngeal carcinomaen_HK
dc.typeArticleen_HK
dc.identifier.emailTsang, RKY: rkytsang@hku.hken_HK
dc.identifier.emailTo, VSH: doctorto@hku.hken_HK
dc.identifier.emailChan, JYW: jywchan1@hku.hken_HK
dc.identifier.emailWei, WI: hrmswwi@hku.hken_HK
dc.identifier.authorityTsang, RKY=rp01386en_HK
dc.identifier.authorityTo, VSH=rp01385en_HK
dc.identifier.authorityChan, JYW=rp01314en_HK
dc.identifier.authorityWei, WI=rp00323en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1002/hed.21781en_HK
dc.identifier.pmid21688342-
dc.identifier.scopuseid_2-s2.0-84859762125en_HK
dc.identifier.hkuros190604en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-84859762125&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume34en_HK
dc.identifier.issue5en_HK
dc.identifier.spage638en_HK
dc.identifier.epage642en_HK
dc.identifier.isiWOS:000302549100005-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridTsang, RKY=7102940058en_HK
dc.identifier.scopusauthoridChung, JCK=22940027200en_HK
dc.identifier.scopusauthoridNg, YW=39962070100en_HK
dc.identifier.scopusauthoridTo, VSH=35957345400en_HK
dc.identifier.scopusauthoridHo, ACW=16202695800en_HK
dc.identifier.scopusauthoridChan, JYW=27171772200en_HK
dc.identifier.scopusauthoridHo, WK=7402968844en_HK
dc.identifier.scopusauthoridWei, WI=7403321552en_HK

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