Article: Three-year incidence and predictors of first-onset of DSM-IV mood, anxiety, and substance use disorders in older adults: Results from wave 2 of the national epidemiologic survey on alcohol and related conditions
| Title | Three-year incidence and predictors of first-onset of DSM-IV mood, anxiety, and substance use disorders in older adults: Results from wave 2 of the national epidemiologic survey on alcohol and related conditions |
|---|---|
| Authors | Chou, KL2 Mackenzie, CS1 Liang, K2 Sareen, J1 |
| Issue Date | 2011 |
| Publisher | Physicians Postgraduate Press, Inc. The Journal's web site is located at http://www.psychiatrist.com |
| Citation | Journal Of Clinical Psychiatry, 2011, v. 72 n. 2, p. 144-155 [How to Cite?] DOI: http://dx.doi.org/10.4088/JCP.09m05618gry |
| Abstract | Objective: The aim of this study was to determine the incidence rates of Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) mood disorders, anxiety disorders, and substance use disorders in older adults and to identify sociodemographic, psychopathological, health-related, and stress-related predictors of onset of these disorders. Method: A nationally representative sample of 8,012 community-dwelling adults aged 60 and above was interviewed twice over a period of 3 years, in 2000-2001 and 2004-2005. First incidence of mood, anxiety, and substance use disorders was assessed over a period of 3 years using the Alcohol Use Disorder and Associated Disabilities Interview Schedule-DSM-IV Version. Results: The 3-year incidence rates of DSM-IV mood, anxiety, and substance use disorders were highest for nicotine dependence (3.38%) and major depressive disorder ([MDD] 3.28%) and lowest for drug use disorder (0.29%) and bipolar II disorder (0.34%). Incidence rates were significantly greater among older women for MDD (99% CI, 1.22-3.13) and generalized anxiety disorder (GAD; 99% CI, 1.20-4.26) and greater among older men for nicotine dependence and alcohol abuse and dependence. Posttraumatic stress disorder predicted incidence of MDD, bipolar I disorder, panic disorder, specific phobia, and GAD, while Cluster B personality disorders predicted incident MDD, bipolar I and II disorders, panic disorder, social phobia, GAD, nicotine dependence, and alcohol dependence. Poor self-rated health increased the risk for the onset of MDD, whereas obesity decreased the incidence of nicotine dependence. Conclusions: Information about disorders that are highly incident in late life and risk factors for the onset of psychiatric disorders among older adults are important for effective early intervention and prevention initiatives. © Copyright 2011 Physicians Postgraduate Press, Inc. |
| ISSN | 0160-6689 2011 Impact Factor: 5.799 2011 SCImago Journal Rankings: 0.262 |
| DOI | http://dx.doi.org/10.4088/JCP.09m05618gry |
| References | References in Scopus |
| Grants | Integration of new immigrants in Hong Kong: a longitudinal investigation |
| dc.contributor.author | Chou, KL | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| dc.contributor.author | Mackenzie, CS | ||||||||
| dc.contributor.author | Liang, K | ||||||||
| dc.contributor.author | Sareen, J | ||||||||
| dc.date.accessioned | 2011-08-26T14:27:12Z | ||||||||
| dc.date.available | 2011-08-26T14:27:12Z | ||||||||
| dc.date.issued | 2011 | ||||||||
| dc.description.abstract | Objective: The aim of this study was to determine the incidence rates of Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) mood disorders, anxiety disorders, and substance use disorders in older adults and to identify sociodemographic, psychopathological, health-related, and stress-related predictors of onset of these disorders. Method: A nationally representative sample of 8,012 community-dwelling adults aged 60 and above was interviewed twice over a period of 3 years, in 2000-2001 and 2004-2005. First incidence of mood, anxiety, and substance use disorders was assessed over a period of 3 years using the Alcohol Use Disorder and Associated Disabilities Interview Schedule-DSM-IV Version. Results: The 3-year incidence rates of DSM-IV mood, anxiety, and substance use disorders were highest for nicotine dependence (3.38%) and major depressive disorder ([MDD] 3.28%) and lowest for drug use disorder (0.29%) and bipolar II disorder (0.34%). Incidence rates were significantly greater among older women for MDD (99% CI, 1.22-3.13) and generalized anxiety disorder (GAD; 99% CI, 1.20-4.26) and greater among older men for nicotine dependence and alcohol abuse and dependence. Posttraumatic stress disorder predicted incidence of MDD, bipolar I disorder, panic disorder, specific phobia, and GAD, while Cluster B personality disorders predicted incident MDD, bipolar I and II disorders, panic disorder, social phobia, GAD, nicotine dependence, and alcohol dependence. Poor self-rated health increased the risk for the onset of MDD, whereas obesity decreased the incidence of nicotine dependence. Conclusions: Information about disorders that are highly incident in late life and risk factors for the onset of psychiatric disorders among older adults are important for effective early intervention and prevention initiatives. © Copyright 2011 Physicians Postgraduate Press, Inc. | ||||||||
| dc.description.grant | Integration of new immigrants in Hong Kong: a longitudinal investigation | ||||||||
| dc.description.grantcode | 82032 | ||||||||
| dc.description.nature | Link_to_subscribed_fulltext | ||||||||
| dc.identifier.citation | Journal Of Clinical Psychiatry, 2011, v. 72 n. 2, p. 144-155 [How to Cite?] DOI: http://dx.doi.org/10.4088/JCP.09m05618gry | ||||||||
| dc.identifier.doi | http://dx.doi.org/10.4088/JCP.09m05618gry | ||||||||
| dc.identifier.epage | 155 | ||||||||
| dc.identifier.hkuros | 189277 | ||||||||
| dc.identifier.isi | WOS:000287985400004
Funding Information: Preparation of this article was supported in part by the Research Grant Council (HKU 7004-PPR20051) to Dr Chou, and a Canadian Institutes of Health Research New Investigator Award to Dr Sareen (#152348). The National Epidemiologic Survey on Alcohol and Related Conditions was conducted and funded by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), with supplemental support from the National Institute on Drug Abuse. | ||||||||
| dc.identifier.issn | 0160-6689 2011 Impact Factor: 5.799 2011 SCImago Journal Rankings: 0.262 | ||||||||
| dc.identifier.issue | 2 | ||||||||
| dc.identifier.pmid | 21382305 | ||||||||
| dc.identifier.scopus | eid_2-s2.0-79951986707 | ||||||||
| dc.identifier.spage | 144 | ||||||||
| dc.identifier.uri | http://hdl.handle.net/10722/137527 | ||||||||
| dc.identifier.volume | 72 | ||||||||
| dc.language | eng | ||||||||
| dc.publisher | Physicians Postgraduate Press, Inc. The Journal's web site is located at http://www.psychiatrist.com | ||||||||
| dc.publisher.place | United States | ||||||||
| dc.relation.ispartof | Journal of Clinical Psychiatry | ||||||||
| dc.relation.references | References in Scopus | ||||||||
| dc.subject.mesh | Alcoholism - diagnosis - epidemiology - psychology | ||||||||
| dc.subject.mesh | Anxiety Disorders - diagnosis - epidemiology - psychology | ||||||||
| dc.subject.mesh | Diagnostic and Statistical Manual of Mental Disorders | ||||||||
| dc.subject.mesh | Mood Disorders - diagnosis - epidemiology - psychology | ||||||||
| dc.subject.mesh | Substance-Related Disorders - diagnosis - epidemiology - psychology | ||||||||
| dc.title | Three-year incidence and predictors of first-onset of DSM-IV mood, anxiety, and substance use disorders in older adults: Results from wave 2 of the national epidemiologic survey on alcohol and related conditions | ||||||||
| dc.type | Article |
Author Affiliations
- University of Manitoba
- The University of Hong Kong

