Article: Plasma-modified biomaterials for self-antimicrobial applications.

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TitlePlasma-modified biomaterials for self-antimicrobial applications.
AuthorsWu, S1
Liu, X
Yeung, A
Yeung, KW
Kao, RY
Wu, G
Hu, T
Xu, Z
Chu, PK
Keywordsantimicrobial
biomaterials
plasma surface modification
self-decontamination
Issue Date2011
PublisherAmerican Chemical Society. The Journal's web site is located at http://pubs.acs.org/journal/aamick
CitationAcs Applied Materials & Interfaces, 2011, v. 3 n. 8, p. 2851-2860 [How to Cite?]
DOI: http://dx.doi.org/10.1021/am2003944
AbstractThe surface compatibility and antibacterial properties of biomaterials are crucial to tissue engineering and other medical applications, and plasma-assisted technologies have been employed to enhance these characteristics with good success. Herein, we describe and review the recent developments made by our interdisciplinary team on self-antimicrobial biomaterials with emphasis on plasma-based surface modification. Our results indicate that a self-antibacterial surface can be produced on various types of materials including polymers, metals, and ceramics by plasma treatment. Surface characteristics such as roughness, microstructure, chemistry, electronegativity, free energy, hydrophilicity, and interfacial physiochemistry are important factors and can be tailored by using the appropriate plasma-assisted processing parameters. In particular, mechanistic studies reveal that the interfacial physiochemical processes, biocidal agents, and surface free energy are predominantly responsible for the antibacterial effects of plasma-modified biomaterials.
ISSN1944-8252
DOIhttp://dx.doi.org/10.1021/am2003944
ISI Accession Number IDWOS:000294146900007
Funding AgencyGrant Number
City University of Hong Kong7008009
9360110
9678021
9678028
9667038
Hong Kong Research Grant Council (RGC)112510
123708
124009
SEG_CityU05
ITFITS 342/09
AO FoundationS-09-75Y
Chinese National High Technology Research and Development 863 Project2009AA02Z416
CityU 9231026
National Natural Science Foundation of China50901032
Ministry of Education Specialized Research Foundation20094208120003
Hubei Provincial Middle-Young Research FundQ20101010
Wuhan ChenGuang Research Programme Grant201150431134
Funding Information:

The work was jointly supported by City University of Hong Kong Strategic Research Grant (SRG) 7008009; City University of Hong Kong Matching Research Grants 9360110, 9678021, and 9678028; City University of Hong Kong Applied Research Grant 9667038; Hong Kong Research Grant Council (RGC) General Research Funds (GRF) 112510, 123708, and 124009; Hong Kong Research Grants Council Special Equipment Grant SEG_CityU05; ITF Tier 3 Program (ITS 342/09); AO Foundation Start-up Grant (S-09-75Y); Chinese National High Technology Research and Development 863 Project 2009AA02Z416 (CityU 9231026); National Natural Science Foundation of China 50901032; Ministry of Education Specialized Research Foundation for Doctoral Program of Universities 20094208120003, Hubei Provincial Middle-Young Research Fund Grant Q20101010; and Wuhan ChenGuang Research Programme Grant 201150431134. We thank the previous and current members of our group for their contributions: Dr. W. Zhang, Dr. J. Wang, Prof. X. Y. Liu, Prof X B. Tian, Dr. F. J. Jing, Dr. S. C. H. Kwok, and Dr. H. Y. Wang.

ReferencesReferences in Scopus
DC Field
Value
dc.contributor.authorWu, S
dc.contributor.authorLiu, X
dc.contributor.authorYeung, A
dc.contributor.authorYeung, KW
dc.contributor.authorKao, RY
dc.contributor.authorWu, G
dc.contributor.authorHu, T
dc.contributor.authorXu, Z
dc.contributor.authorChu, PK
dc.date.accessioned2011-08-26T14:25:29Z
dc.date.available2011-08-26T14:25:29Z
dc.date.issued2011
dc.description.abstractThe surface compatibility and antibacterial properties of biomaterials are crucial to tissue engineering and other medical applications, and plasma-assisted technologies have been employed to enhance these characteristics with good success. Herein, we describe and review the recent developments made by our interdisciplinary team on self-antimicrobial biomaterials with emphasis on plasma-based surface modification. Our results indicate that a self-antibacterial surface can be produced on various types of materials including polymers, metals, and ceramics by plasma treatment. Surface characteristics such as roughness, microstructure, chemistry, electronegativity, free energy, hydrophilicity, and interfacial physiochemistry are important factors and can be tailored by using the appropriate plasma-assisted processing parameters. In particular, mechanistic studies reveal that the interfacial physiochemical processes, biocidal agents, and surface free energy are predominantly responsible for the antibacterial effects of plasma-modified biomaterials.
dc.description.natureLink_to_subscribed_fulltext
dc.identifier.citationAcs Applied Materials & Interfaces, 2011, v. 3 n. 8, p. 2851-2860 [How to Cite?]
DOI: http://dx.doi.org/10.1021/am2003944
dc.identifier.doihttp://dx.doi.org/10.1021/am2003944
dc.identifier.epage2860
dc.identifier.hkuros192004
dc.identifier.isiWOS:000294146900007
Funding AgencyGrant Number
City University of Hong Kong7008009
9360110
9678021
9678028
9667038
Hong Kong Research Grant Council (RGC)112510
123708
124009
SEG_CityU05
ITFITS 342/09
AO FoundationS-09-75Y
Chinese National High Technology Research and Development 863 Project2009AA02Z416
CityU 9231026
National Natural Science Foundation of China50901032
Ministry of Education Specialized Research Foundation20094208120003
Hubei Provincial Middle-Young Research FundQ20101010
Wuhan ChenGuang Research Programme Grant201150431134
Funding Information:

The work was jointly supported by City University of Hong Kong Strategic Research Grant (SRG) 7008009; City University of Hong Kong Matching Research Grants 9360110, 9678021, and 9678028; City University of Hong Kong Applied Research Grant 9667038; Hong Kong Research Grant Council (RGC) General Research Funds (GRF) 112510, 123708, and 124009; Hong Kong Research Grants Council Special Equipment Grant SEG_CityU05; ITF Tier 3 Program (ITS 342/09); AO Foundation Start-up Grant (S-09-75Y); Chinese National High Technology Research and Development 863 Project 2009AA02Z416 (CityU 9231026); National Natural Science Foundation of China 50901032; Ministry of Education Specialized Research Foundation for Doctoral Program of Universities 20094208120003, Hubei Provincial Middle-Young Research Fund Grant Q20101010; and Wuhan ChenGuang Research Programme Grant 201150431134. We thank the previous and current members of our group for their contributions: Dr. W. Zhang, Dr. J. Wang, Prof. X. Y. Liu, Prof X B. Tian, Dr. F. J. Jing, Dr. S. C. H. Kwok, and Dr. H. Y. Wang.

dc.identifier.issn1944-8252
dc.identifier.issue8
dc.identifier.pmid21668027
dc.identifier.scopuseid_2-s2.0-84855171884
dc.identifier.spage2851
dc.identifier.urihttp://hdl.handle.net/10722/137460
dc.identifier.volume3
dc.languageeng
dc.publisherAmerican Chemical Society. The Journal's web site is located at http://pubs.acs.org/journal/aamick
dc.publisher.placeUnited States
dc.relation.ispartofACS applied materials & interfaces
dc.relation.referencesReferences in Scopus
dc.subject.meshAnti-Infective Agents - chemistry - pharmacology
dc.subject.meshBiocompatible Materials - chemistry - pharmacology
dc.subject.meshCeramics - chemistry - pharmacology
dc.subject.meshMetals - chemistry - pharmacology
dc.subject.meshTitanium - chemistry
dc.subjectantimicrobial
dc.subjectbiomaterials
dc.subjectplasma surface modification
dc.subjectself-decontamination
dc.titlePlasma-modified biomaterials for self-antimicrobial applications.
dc.typeArticle
Author Affiliations
  1. City University of Hong Kong