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Article: Atypical burkitt's lymphoma transforming from follicular lymphoma

TitleAtypical burkitt's lymphoma transforming from follicular lymphoma
Authors
Issue Date2011
PublisherBioMed Central Ltd. The Journal's web site is located at http://www.diagnosticpathology.org
Citation
Diagnostic Pathology, 2011, v. 6 n. 1, article no. 63 How to Cite?
AbstractAmongst follicular lymphoma that transforms into a high-grade lymphoma, majority are diffuse large B cell lymphoma. Here we reported a rare atypical Burkitt's lymphoma transformation from an asymptomatic follicular lymphoma. Lymph node biopsy showed a composite lymphoma with infiltration of the inter-follicular areas by high grade small non-cleaved lymphoma cells amongst neoplastic follicles. Moreover, FISH and molecular genetic study confirmed concomitant MYC translocations and t(14;18) in the high-grade component, thereby suggesting the transformation of atypical Burkitt's lymphoma from an undiagnosed antecedent follicular lymphoma. The disease followed an aggressive clinical course, terminating in refractory disease 13 months after diagnosis. This is followed by a comprehensive review of the literature on lymphoma transformations from underlying follicular lymphoma after acquisition of MYC translocation, using Burkitt's lymphoma, follicular lymphoma, transformation and MYC translocations as keywords. © 2011 Hwang et al; licensee BioMed Central Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/137365
ISSN
2015 Impact Factor: 1.895
2015 SCImago Journal Rankings: 0.775
PubMed Central ID
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorHwang, YYen_HK
dc.contributor.authorLoong, Fen_HK
dc.contributor.authorChung, LPen_HK
dc.contributor.authorChim, CSen_HK
dc.date.accessioned2011-08-26T14:23:57Z-
dc.date.available2011-08-26T14:23:57Z-
dc.date.issued2011en_HK
dc.identifier.citationDiagnostic Pathology, 2011, v. 6 n. 1, article no. 63en_HK
dc.identifier.issn1746-1596en_HK
dc.identifier.urihttp://hdl.handle.net/10722/137365-
dc.description.abstractAmongst follicular lymphoma that transforms into a high-grade lymphoma, majority are diffuse large B cell lymphoma. Here we reported a rare atypical Burkitt's lymphoma transformation from an asymptomatic follicular lymphoma. Lymph node biopsy showed a composite lymphoma with infiltration of the inter-follicular areas by high grade small non-cleaved lymphoma cells amongst neoplastic follicles. Moreover, FISH and molecular genetic study confirmed concomitant MYC translocations and t(14;18) in the high-grade component, thereby suggesting the transformation of atypical Burkitt's lymphoma from an undiagnosed antecedent follicular lymphoma. The disease followed an aggressive clinical course, terminating in refractory disease 13 months after diagnosis. This is followed by a comprehensive review of the literature on lymphoma transformations from underlying follicular lymphoma after acquisition of MYC translocation, using Burkitt's lymphoma, follicular lymphoma, transformation and MYC translocations as keywords. © 2011 Hwang et al; licensee BioMed Central Ltd.en_HK
dc.languageengen_US
dc.publisherBioMed Central Ltd. The Journal's web site is located at http://www.diagnosticpathology.orgen_HK
dc.relation.ispartofDiagnostic Pathologyen_HK
dc.rightsDiagnostic Pathology. Copyright © BioMed Central Ltd.en_US
dc.titleAtypical burkitt's lymphoma transforming from follicular lymphomaen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1746-1596&volume=6&spage=63&epage=&date=2011&atitle=Atypical+Burkitt’s+lymphoma+transforming+from+follicular+lymphomaen_US
dc.identifier.emailChung, LP: lpchung@hkucc.hku.hken_HK
dc.identifier.emailChim, CS: jcschim@hku.hken_HK
dc.identifier.authorityChung, LP=rp00249en_HK
dc.identifier.authorityChim, CS=rp00408en_HK
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1186/1746-1596-6-63en_HK
dc.identifier.pmid21736761-
dc.identifier.pmcidPMC3143916-
dc.identifier.scopuseid_2-s2.0-79960700355en_HK
dc.identifier.hkuros189625en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-79960700355&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume6en_HK
dc.identifier.issue1en_HK
dc.identifier.spage63en_US
dc.identifier.epage63en_US
dc.identifier.isiWOS:000293134200001-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridHwang, YY=18134023400en_HK
dc.identifier.scopusauthoridLoong, F=6602794154en_HK
dc.identifier.scopusauthoridChung, LP=24315879100en_HK
dc.identifier.scopusauthoridChim, CS=7004597253en_HK
dc.identifier.citeulike9546435-

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