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Conference Paper: Rapid measurement of indocyanine green clearance by pulse spectrophotometry: a validation study in 70 patients with Child-pugh A liver function
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TitleRapid measurement of indocyanine green clearance by pulse spectrophotometry: a validation study in 70 patients with Child-pugh A liver function
 
AuthorsCheung, TT
Chan, SC
Poon, RTP
Lo, CM
Fan, ST
 
KeywordsMedical sciences
Endocrinology
 
Issue Date2011
 
PublisherSpringer New York LLC. The Journal's web site is located at http://www.springer.com/west/home/medicine?SGWID=4-10054-70-173733513-0
 
CitationThe 21st Conferece of the Asian Pacific Association for the Study of the Liver (APASL 2011), Bangkok, Thailand, 17-20 February 2011. In Hepatology International, 2011, v. 5 n. 1, p. 464, abstract PP34-21 [How to Cite?]
DOI: http://dx.doi.org/10.1007/s12072-010-9241-z
 
AbstractBACKGROUND: Inadequate liver functional reserve is the greatest barrier for major hepatectomy in patients with hepatocellular carcinoma and liver cirrhosis. The development of pulse spectrophotometry provides a faster alternative for ICG measurement but its accuracy in for preoperative assessment is not well documented as most of the previous studies consisted of a heterogenous group of patients in the critically ill patients. This study compared the result of non-invasive liver function monitoring using the LiMON (Pulsion Medical System, Munich, Germany) and traditional spectrophotometry by serial blood sampling in patient with Pugh Child A score before major hepatic resection. STUDY DESIGN: From September 2008 to Jan 2009, 70 patients with Pugh Child A score were enrolled for investigations. Their ICG clearance at 15 min were measured by traditional spectrophotometry with serial blood sampling and the LiMON. The results were compared. RESULTS: The median ICG retention at 15 min by spectrophotometry was 14.748%. The median ICGR15 measured by LiMON was 10.38. The mean difference between the LiMON and spectrophotometry was -4.3606. There was a strong correlation between the 2 measurement methods (correlation coefficient 0.844, 95% CI = 0.762, 0.899). The ICGR15 measured by LiMON, the ICG15 measured by traditional method can be calculated using the following formula. ICG15 = 1.16 * ICGR15 + 2.73 Conclusions: The LiMON is a portable unit which provides a fast and repeatable method to evaluate the ICG clearance at 15 min for patient with Pugh Child A Score. Adjustment of result is necessary in order to achieve a comparable result obtained by spectrophotometry.
 
Descriptionpp. 3-558 of this journal issue contain Abstracts of the 21st APASL Conference 2011
 
ISSN1936-0533
2013 Impact Factor: 2.468
 
DOIhttp://dx.doi.org/10.1007/s12072-010-9241-z
 
DC FieldValue
dc.contributor.authorCheung, TT
 
dc.contributor.authorChan, SC
 
dc.contributor.authorPoon, RTP
 
dc.contributor.authorLo, CM
 
dc.contributor.authorFan, ST
 
dc.date.accessioned2011-07-27T02:02:46Z
 
dc.date.available2011-07-27T02:02:46Z
 
dc.date.issued2011
 
dc.description.abstractBACKGROUND: Inadequate liver functional reserve is the greatest barrier for major hepatectomy in patients with hepatocellular carcinoma and liver cirrhosis. The development of pulse spectrophotometry provides a faster alternative for ICG measurement but its accuracy in for preoperative assessment is not well documented as most of the previous studies consisted of a heterogenous group of patients in the critically ill patients. This study compared the result of non-invasive liver function monitoring using the LiMON (Pulsion Medical System, Munich, Germany) and traditional spectrophotometry by serial blood sampling in patient with Pugh Child A score before major hepatic resection. STUDY DESIGN: From September 2008 to Jan 2009, 70 patients with Pugh Child A score were enrolled for investigations. Their ICG clearance at 15 min were measured by traditional spectrophotometry with serial blood sampling and the LiMON. The results were compared. RESULTS: The median ICG retention at 15 min by spectrophotometry was 14.748%. The median ICGR15 measured by LiMON was 10.38. The mean difference between the LiMON and spectrophotometry was -4.3606. There was a strong correlation between the 2 measurement methods (correlation coefficient 0.844, 95% CI = 0.762, 0.899). The ICGR15 measured by LiMON, the ICG15 measured by traditional method can be calculated using the following formula. ICG15 = 1.16 * ICGR15 + 2.73 Conclusions: The LiMON is a portable unit which provides a fast and repeatable method to evaluate the ICG clearance at 15 min for patient with Pugh Child A Score. Adjustment of result is necessary in order to achieve a comparable result obtained by spectrophotometry.
 
dc.descriptionpp. 3-558 of this journal issue contain Abstracts of the 21st APASL Conference 2011
 
dc.description.otherThe 21st Conferece of the Asian Pacific Association for the Study of the Liver (APASL 2011), Bangkok, Thailand, 17-20 February 2011. In Hepatology International, 2011, v. 5 n. 1, p. 464, abstract PP34-21
 
dc.identifier.citationThe 21st Conferece of the Asian Pacific Association for the Study of the Liver (APASL 2011), Bangkok, Thailand, 17-20 February 2011. In Hepatology International, 2011, v. 5 n. 1, p. 464, abstract PP34-21 [How to Cite?]
DOI: http://dx.doi.org/10.1007/s12072-010-9241-z
 
dc.identifier.doihttp://dx.doi.org/10.1007/s12072-010-9241-z
 
dc.identifier.epage464
 
dc.identifier.hkuros188347
 
dc.identifier.issn1936-0533
2013 Impact Factor: 2.468
 
dc.identifier.issue1
 
dc.identifier.spage464
 
dc.identifier.urihttp://hdl.handle.net/10722/136097
 
dc.identifier.volume5
 
dc.languageeng
 
dc.publisherSpringer New York LLC. The Journal's web site is located at http://www.springer.com/west/home/medicine?SGWID=4-10054-70-173733513-0
 
dc.publisher.placeUnited States
 
dc.relation.ispartofHepatology International
 
dc.rightsThe original publication is available at www.springerlink.com
 
dc.subjectMedical sciences
 
dc.subjectEndocrinology
 
dc.titleRapid measurement of indocyanine green clearance by pulse spectrophotometry: a validation study in 70 patients with Child-pugh A liver function
 
dc.typeConference_Paper
 
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<contributor.author>Fan, ST</contributor.author>
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