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Conference Paper: Remineralizing action of CPP-ACP reagents on artificial carious lesions

TitleRemineralizing action of CPP-ACP reagents on artificial carious lesions
Authors
Issue Date2011
PublisherWiley-Blackwell Publishing Ltd.. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=0960-7439
Citation
The 23rd Congress of the International Association of Paediatric Dentistry, Athens, Greece, 15-18 June 2011. In International Journal of Paediatric Dentistry, 2011, v. 21 suppl. s1, p. 31, abstract no: O10-90 How to Cite?
AbstractAIM: To evaluate the efficacy of CPP-ACP containing pastes; Clinpro® (500 ppm tri-calcium phosphate +950 ppm sodium fluoride) and Tooth Mousse Plus® (10% CPP-ACP + 900 ppm sodium fluoride) in remineralizing artificial enamel carious lesions. DESIGN: Fifty extracted human third molars were cleaned of soft tissue debris and inspected for any cracks, caries or hypoplasia. The teeth were painted with an acid resistant nail varnish leaving a 1 mm window on the buccal and lingual surfaces and then immersed in a demineralizing solution for 96 h, to produce artificial carious lesions 90–180 lm deep. Subsequently, the teeth were sectioned longitudinally through the lesion to produce sections that were approximately 100–150 lm thick. The tooth specimens were randomly divided into four groups (n = 29) and treated with a non-fluoridated or fluoridated paste (for 1 min), Clinpro® or TM Plus® pastes (for 3 min) in a 10 day pH cycling model. Lesion depth (LD) and mineral content (Vmax) for each specimen were evaluated using polarized light microscopy (PLM) and microradiography (MRG) before and after the pH cycle. Paired t-test, ANOVA and Student-Newman–Keuls tests were employed to make comparisons within, and between the different treatment groups. RESULTS: Significant differences were evident when comparisons were made between the pre- and post-treatment specimens within each group. When multiple comparisons were made, specimens treated with Clinpro® exhibited the greatest reduction in LD and increase in Vmax as compared to the other treatment groups. CONCLUSION: A three minute application of Clinpro® exhibited a higher efficacy in remineralizing artificial enamel carious lesions than TM Plus®.
DescriptionThis journal supplement is Special Issue: Abstracts of the 23rd Congress of the International Association of Paediatric Dentistry, 2011
Oral Session O10 - Cariology 3: abstract no. O10-90
Persistent Identifierhttp://hdl.handle.net/10722/135742
ISSN
2015 Impact Factor: 1.303
2015 SCImago Journal Rankings: 0.721

 

DC FieldValueLanguage
dc.contributor.authorBuckshey, Sen_US
dc.contributor.authorAnthonappa, Ren_US
dc.contributor.authorKing, Nen_US
dc.contributor.authorItthagarun, Aen_US
dc.date.accessioned2011-07-27T01:47:41Z-
dc.date.available2011-07-27T01:47:41Z-
dc.date.issued2011en_US
dc.identifier.citationThe 23rd Congress of the International Association of Paediatric Dentistry, Athens, Greece, 15-18 June 2011. In International Journal of Paediatric Dentistry, 2011, v. 21 suppl. s1, p. 31, abstract no: O10-90en_US
dc.identifier.issn0960-7439en_US
dc.identifier.urihttp://hdl.handle.net/10722/135742-
dc.descriptionThis journal supplement is Special Issue: Abstracts of the 23rd Congress of the International Association of Paediatric Dentistry, 2011en_US
dc.descriptionOral Session O10 - Cariology 3: abstract no. O10-90-
dc.description.abstractAIM: To evaluate the efficacy of CPP-ACP containing pastes; Clinpro® (500 ppm tri-calcium phosphate +950 ppm sodium fluoride) and Tooth Mousse Plus® (10% CPP-ACP + 900 ppm sodium fluoride) in remineralizing artificial enamel carious lesions. DESIGN: Fifty extracted human third molars were cleaned of soft tissue debris and inspected for any cracks, caries or hypoplasia. The teeth were painted with an acid resistant nail varnish leaving a 1 mm window on the buccal and lingual surfaces and then immersed in a demineralizing solution for 96 h, to produce artificial carious lesions 90–180 lm deep. Subsequently, the teeth were sectioned longitudinally through the lesion to produce sections that were approximately 100–150 lm thick. The tooth specimens were randomly divided into four groups (n = 29) and treated with a non-fluoridated or fluoridated paste (for 1 min), Clinpro® or TM Plus® pastes (for 3 min) in a 10 day pH cycling model. Lesion depth (LD) and mineral content (Vmax) for each specimen were evaluated using polarized light microscopy (PLM) and microradiography (MRG) before and after the pH cycle. Paired t-test, ANOVA and Student-Newman–Keuls tests were employed to make comparisons within, and between the different treatment groups. RESULTS: Significant differences were evident when comparisons were made between the pre- and post-treatment specimens within each group. When multiple comparisons were made, specimens treated with Clinpro® exhibited the greatest reduction in LD and increase in Vmax as compared to the other treatment groups. CONCLUSION: A three minute application of Clinpro® exhibited a higher efficacy in remineralizing artificial enamel carious lesions than TM Plus®.en_US
dc.languageengen_US
dc.publisherWiley-Blackwell Publishing Ltd.. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=0960-7439en_US
dc.relation.ispartofInternational Journal of Paediatric Dentistryen_US
dc.rightsThe definitive version is available at www3.interscience.wiley.comen_US
dc.titleRemineralizing action of CPP-ACP reagents on artificial carious lesionsen_US
dc.typeConference_Paperen_US
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1365-263X&volume=21 &issue=s1&spage=31 (Abst No: O10&epage=90)&date=2011&atitle=Remineralizing+action+of+CPP-ACP+reagents+on+artificial+carious+lesionsen_US
dc.identifier.emailBuckshey, S: sakshi@hku.hken_US
dc.identifier.emailAnthonappa, R: h0496932@hku.hken_US
dc.identifier.emailKing, N: hhdbknm@hkucc.hku.hk-
dc.identifier.emailItthagarun, A: aitthaga@hku.hk-
dc.identifier.authorityKing, N=rp00006en_US
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1111/j.1365-263X.2011.01137.xen_US
dc.identifier.hkuros187234en_US
dc.identifier.volume21en_US
dc.identifier.issuesuppl. s1en_US
dc.identifier.spage31en_US
dc.identifier.epage31en_US
dc.publisher.placeUnited Kingdom-
dc.description.otherThe 23rd Congress of the International Association of Paediatric Dentistry, Athens, Greece, 15-18 June 2011. In International Journal of Paediatric Dentistry, 2011, v. 21 suppl. s1, p. 31, abstract no: O10-90-

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