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Conference Paper: The regional distribution of different types of influenza receptors in cultured human alveolar epithelial cells and correlation with in vitro infection

TitleThe regional distribution of different types of influenza receptors in cultured human alveolar epithelial cells and correlation with in vitro infection
Authors
KeywordsMaackia amurensis agglutinin
Sambucus nigra agglutnin
Sialic acid receptors
Type II pneumocytes
Type-I-like pneumocytes
Issue Date2011
PublisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/subs.asp?ref=1750-2640&site=1
Citation
The 2010 International Scientific Conference of Options for the Control of Influenza (Options-7), Hong Kong SAR, China, 3-7 September 2010. In Influenza and Other Respiratory Viruses, 2011, v. 5 n. S1, p. 436-437 How to Cite?
AbstractBACKGROUND: Sialic acid (Sia) linked glycoproteins are the classical influenza receptors for influenza virus haemagglutinin to bind. The distribution of Sia on cell surfaces is one of the determinants of host tropism, and understanding its expression on human cells and tissues is important for understanding influenza pathogenesis. Previous research has shown the differences in apical versus basolateral infection and release of different influenza virus from polarized epithelial cells1 and correlated this with sialic acid distribution in the human respiratory tract. Moreover, mass spectrometric analysis was recently employed to elucidate the glycans present in the tissue in a higher resolution in human lung.2 The objective of this study was to examine in detail the distribution of these Sia-linked glycans at the cellular level by the use of confocal microscopy …
Persistent Identifierhttp://hdl.handle.net/10722/135685
ISSN
2015 Impact Factor: 2.378
2015 SCImago Journal Rankings: 1.570

 

DC FieldValueLanguage
dc.contributor.authorHui, CFFen_US
dc.contributor.authorChan, RWYen_US
dc.contributor.authorFung, KHYen_US
dc.contributor.authorYu, WCLen_US
dc.contributor.authorTsao, GSWen_US
dc.contributor.authorChan, MCWen_US
dc.contributor.authorNicholls, JMen_US
dc.date.accessioned2011-07-27T01:39:24Z-
dc.date.available2011-07-27T01:39:24Z-
dc.date.issued2011en_US
dc.identifier.citationThe 2010 International Scientific Conference of Options for the Control of Influenza (Options-7), Hong Kong SAR, China, 3-7 September 2010. In Influenza and Other Respiratory Viruses, 2011, v. 5 n. S1, p. 436-437en_US
dc.identifier.issn1750-2640-
dc.identifier.urihttp://hdl.handle.net/10722/135685-
dc.description.abstractBACKGROUND: Sialic acid (Sia) linked glycoproteins are the classical influenza receptors for influenza virus haemagglutinin to bind. The distribution of Sia on cell surfaces is one of the determinants of host tropism, and understanding its expression on human cells and tissues is important for understanding influenza pathogenesis. Previous research has shown the differences in apical versus basolateral infection and release of different influenza virus from polarized epithelial cells1 and correlated this with sialic acid distribution in the human respiratory tract. Moreover, mass spectrometric analysis was recently employed to elucidate the glycans present in the tissue in a higher resolution in human lung.2 The objective of this study was to examine in detail the distribution of these Sia-linked glycans at the cellular level by the use of confocal microscopy …-
dc.languageengen_US
dc.publisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/subs.asp?ref=1750-2640&site=1-
dc.relation.ispartofInfluenza and Other Respiratory Virusesen_US
dc.rightsThe definitive version is available at www.blackwell-synergy.com-
dc.subjectMaackia amurensis agglutinin-
dc.subjectSambucus nigra agglutnin-
dc.subjectSialic acid receptors-
dc.subjectType II pneumocytes-
dc.subjectType-I-like pneumocytes-
dc.titleThe regional distribution of different types of influenza receptors in cultured human alveolar epithelial cells and correlation with in vitro infectionen_US
dc.typeConference_Paperen_US
dc.identifier.emailHui, CFF: celineh@hku.hken_US
dc.identifier.emailChan, RWY: reneewy@hku.hken_US
dc.identifier.emailFung, KHY: kfung@hkucc.hku.hken_US
dc.identifier.emailYu, WCL: wendyucl@hkucc.hku.hken_US
dc.identifier.emailTsao, GSW: gswtsao@hkucc.hku.hken_US
dc.identifier.emailChan, MCW: mchan@hku.hken_US
dc.identifier.emailNicholls, JM: jmnichol@hkucc.hku.hken_US
dc.identifier.authorityChan, RWY=rp01596en_US
dc.identifier.authorityTsao, GSW=rp00399en_US
dc.identifier.authorityChan, MCW=rp00420en_US
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1111/j.1750-2659.2011.00209.x-
dc.identifier.hkuros187325en_US
dc.identifier.hkuros187324-
dc.identifier.hkuros170683-
dc.identifier.volume5en_US
dc.identifier.issueS1en_US
dc.identifier.spage436en_US
dc.identifier.epage437en_US
dc.publisher.placeUnited Kingdom-

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