File Download
  Links for fulltext
     (May Require Subscription)

Conference Paper: Replication of avian and seasonal influenza viruses in human bronchus and lung

TitleReplication of avian and seasonal influenza viruses in human bronchus and lung
Authors
KeywordsEx vivo human bronchus culture
Ex vivo lung culture
Influenza A virus
Tissue tropism
Issue Date2011
PublisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/subs.asp?ref=1750-2640&site=1
Citation
The 2010 International Scientific Conference of Options for the Control of Influenza (Options-7), Hong Kong SAR, China, 3-7 September 2010. In Influenza and Other Respiratory Viruses, 2011, v. 5 suppl. 1, p. 425-426 How to Cite?
AbstractBACKGROUND: Pandemics of 1957 and 1968 were believed to arise from avian influenza viruses.1 The tropism of avian and human seasonal influenza viruses for the human lower respiratory tract deserves investigation. The target cell types that support replication of avian influenza A viruses in the human respiratory tract in the early stages of clinical infection have not well defined. In a previous autopsy studies of human H5N1 disease, influenza A virus were found to infect alveolar epithelial cells2 and macrophages.3 In this study, viral infectivity and replication competence of human and high and low pathogenic avian influenza viruses were systematically investigated in the human conducting and lower respiratory tract using ex vivo organ cultures. We compared the replication kinetics of human seasonal influenza viruses (H1N1 and H3N2), low pathogenic avian influenza viruses (H9N2, H5N8) with that of the highly pathogenic H5N1 viruses isolated from human H5N1 disease …
Persistent Identifierhttp://hdl.handle.net/10722/135683
ISSN
2015 Impact Factor: 2.378
2015 SCImago Journal Rankings: 1.570

 

DC FieldValueLanguage
dc.contributor.authorChan, RWYen_US
dc.contributor.authorYuen, KKMen_US
dc.contributor.authorYu, WCLen_US
dc.contributor.authorTang, LLSen_US
dc.contributor.authorLi, ACLen_US
dc.contributor.authorNicholls, JMen_US
dc.contributor.authorChan, MCWen_US
dc.date.accessioned2011-07-27T01:39:22Z-
dc.date.available2011-07-27T01:39:22Z-
dc.date.issued2011en_US
dc.identifier.citationThe 2010 International Scientific Conference of Options for the Control of Influenza (Options-7), Hong Kong SAR, China, 3-7 September 2010. In Influenza and Other Respiratory Viruses, 2011, v. 5 suppl. 1, p. 425-426en_US
dc.identifier.issn1750-2640-
dc.identifier.urihttp://hdl.handle.net/10722/135683-
dc.description.abstractBACKGROUND: Pandemics of 1957 and 1968 were believed to arise from avian influenza viruses.1 The tropism of avian and human seasonal influenza viruses for the human lower respiratory tract deserves investigation. The target cell types that support replication of avian influenza A viruses in the human respiratory tract in the early stages of clinical infection have not well defined. In a previous autopsy studies of human H5N1 disease, influenza A virus were found to infect alveolar epithelial cells2 and macrophages.3 In this study, viral infectivity and replication competence of human and high and low pathogenic avian influenza viruses were systematically investigated in the human conducting and lower respiratory tract using ex vivo organ cultures. We compared the replication kinetics of human seasonal influenza viruses (H1N1 and H3N2), low pathogenic avian influenza viruses (H9N2, H5N8) with that of the highly pathogenic H5N1 viruses isolated from human H5N1 disease …-
dc.languageengen_US
dc.publisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/subs.asp?ref=1750-2640&site=1-
dc.relation.ispartofInfluenza and Other Respiratory Virusesen_US
dc.rightsThe definitive version is available at www.blackwell-synergy.com-
dc.subjectEx vivo human bronchus culture-
dc.subjectEx vivo lung culture-
dc.subjectInfluenza A virus-
dc.subjectTissue tropism-
dc.titleReplication of avian and seasonal influenza viruses in human bronchus and lungen_US
dc.typeConference_Paperen_US
dc.identifier.emailChan, RWY: reneewy@hku.hken_US
dc.identifier.emailYu, WCL: wendyucl@hkucc.hku.hken_US
dc.identifier.emailTang, LLS: lynsia@hku.hken_US
dc.identifier.emailLi, ACL: alancl@hku.hken_US
dc.identifier.emailNicholls, JM: jmnichol@hkucc.hku.hken_US
dc.identifier.emailChan, MCW: mchan@hku.hken_US
dc.identifier.authorityChan, RWY=rp01596en_US
dc.identifier.authorityNicholls, JM=rp00364en_US
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1111/j.1750-2659.2011.00209.x-
dc.identifier.hkuros187322en_US
dc.identifier.hkuros170685-
dc.identifier.volume5en_US
dc.identifier.issuesuppl. 1-
dc.identifier.spage425en_US
dc.identifier.epage426en_US
dc.identifier.eissn1750-2659-
dc.publisher.placeUnited Kingdom-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats