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Article: The Iowa Gambling Task in fMRI images

TitleThe Iowa Gambling Task in fMRI images
Authors
KeywordsDecision making
fMRI
IGT
Somatic marker hypothesis
Issue Date2010
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/38751
Citation
Human Brain Mapping, 2010, v. 31 n. 3, p. 410-423 How to Cite?
AbstractThe Iowa Gambling Task (IGT) is a sensitive test for the detection of decision-making impairments in several neurological and psychiatric populations. Very few studies have employed the IGT in functional magnetic resonance imaging (fMRI) investigations, in part, because the task is cognitively complex. Here we report a method for exploring brain activity using fMRI during performance of the IGT. Decision-making during the IGT was associated with activity in several brain regions in a group of healthy individuals. The activated regions were consistent with the neural circuitry hypothesized to underlie somatic marker activation and decision-making. Specifically, a neural circuitry involving the dorsolateral prefrontal cortex (for working memory), the insula and posterior cingulate cortex (for representations of emotional states), the mesial orbitofrontal and ventromedial prefrontal cortex (for coupling the two previous processes), the ventral striatum and anterior cingulate/SMA (supplementary motor area) for implementing behavioral decisions was engaged. These results have implications for using the IGT to study abnormal mechanisms of decision making in a variety of clinical populations. © 2009 Wiley-Liss, Inc.
Persistent Identifierhttp://hdl.handle.net/10722/135571
ISSN
2015 Impact Factor: 4.962
2015 SCImago Journal Rankings: 3.165
PubMed Central ID
ISI Accession Number ID
Funding AgencyGrant Number
National Institute on Drug Abuse (NIDA)DA11779
DA12487
DA16708
National Science Foundation (NSF)IIS 04-42586
Funding Information:

Contract grant sponsor: National Institute on Drug Abuse (NIDA); Contract grant numbers: DA11779, DA12487, DA16708; Contract grant sponsor: National Science Foundation (NSF), Contract grant number: IIS 04-42586.

References

 

DC FieldValueLanguage
dc.contributor.authorLi, Xen_HK
dc.contributor.authorLu, ZLen_HK
dc.contributor.authorD'Argembeau, Aen_HK
dc.contributor.authorNg, Men_HK
dc.contributor.authorBechara, Aen_HK
dc.date.accessioned2011-07-27T01:37:20Z-
dc.date.available2011-07-27T01:37:20Z-
dc.date.issued2010en_HK
dc.identifier.citationHuman Brain Mapping, 2010, v. 31 n. 3, p. 410-423en_HK
dc.identifier.issn1065-9471en_HK
dc.identifier.urihttp://hdl.handle.net/10722/135571-
dc.description.abstractThe Iowa Gambling Task (IGT) is a sensitive test for the detection of decision-making impairments in several neurological and psychiatric populations. Very few studies have employed the IGT in functional magnetic resonance imaging (fMRI) investigations, in part, because the task is cognitively complex. Here we report a method for exploring brain activity using fMRI during performance of the IGT. Decision-making during the IGT was associated with activity in several brain regions in a group of healthy individuals. The activated regions were consistent with the neural circuitry hypothesized to underlie somatic marker activation and decision-making. Specifically, a neural circuitry involving the dorsolateral prefrontal cortex (for working memory), the insula and posterior cingulate cortex (for representations of emotional states), the mesial orbitofrontal and ventromedial prefrontal cortex (for coupling the two previous processes), the ventral striatum and anterior cingulate/SMA (supplementary motor area) for implementing behavioral decisions was engaged. These results have implications for using the IGT to study abnormal mechanisms of decision making in a variety of clinical populations. © 2009 Wiley-Liss, Inc.en_HK
dc.languageengen_US
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/38751en_HK
dc.relation.ispartofHuman Brain Mappingen_HK
dc.rightsHuman Brain Mapping. Copyright © John Wiley & Sons, Inc.-
dc.subjectDecision makingen_HK
dc.subjectfMRIen_HK
dc.subjectIGTen_HK
dc.subjectSomatic marker hypothesisen_HK
dc.subject.meshBrain - physiology-
dc.subject.meshBrain Mapping - methods-
dc.subject.meshDecision Making - physiology-
dc.subject.meshGambling-
dc.subject.meshMagnetic Resonance Imaging - methods-
dc.titleThe Iowa Gambling Task in fMRI imagesen_HK
dc.typeArticleen_HK
dc.identifier.emailNg, M: marieng@hku.hken_HK
dc.identifier.authorityNg, M=rp01451en_HK
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1002/hbm.20875en_HK
dc.identifier.pmid19777556en_HK
dc.identifier.pmcidPMC2826566-
dc.identifier.scopuseid_2-s2.0-77149145482en_HK
dc.identifier.hkuros186485en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-77149145482&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume31en_HK
dc.identifier.issue3en_HK
dc.identifier.spage410en_HK
dc.identifier.epage423en_HK
dc.identifier.isiWOS:000275380600007-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridLi, X=7501706525en_HK
dc.identifier.scopusauthoridLu, ZL=7404769411en_HK
dc.identifier.scopusauthoridD'Argembeau, A=6603105688en_HK
dc.identifier.scopusauthoridNg, M=36155754200en_HK
dc.identifier.scopusauthoridBechara, A=7003582694en_HK
dc.identifier.citeulike7546391-

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