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Article: Laparoscopic liver resection for hepatocellular carcinoma
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TitleLaparoscopic liver resection for hepatocellular carcinoma
 
AuthorsChung, CD1
Lau, LL1
Ko, KL1
Wong, AC1
Wong, S1
Chan, AC1 2
Poon, RT1
Lo, CM1
Fan, ST1
 
Keywordshepatocellular carcinoma
laparoscopic liver resection
 
Issue Date2010
 
PublisherElsevier (Singapore) Pte Ltd, Hong Kong Branch. The Journal's web site is located at http://www.elsevier.com/wps/find/journaldescription.cws_home/708511/description#description
 
CitationAsian Journal Of Surgery, 2010, v. 33 n. 4, p. 168-172 [How to Cite?]
DOI: http://dx.doi.org/10.1016/S1015-9584(11)60002-X
 
AbstractOBJECTIVE: To provide an updated review on the clinical experience in laparoscopic liver resection, specifically for hepatocellular carcinoma. METHODS: A comprehensive literature search in MEDLINE was conducted for all English papers up to May 2010 on laparoscopic liver resection for hepatocellular carcinoma. Patient characteristics, perioperative results, and oncologic outcomes were compared and analysed. RESULTS: We analysed 11 clinical studies involving 466 hepatocellular carcinoma patients treated with laparoscopic hepatectomy. Thirty-seven (9%) patients underwent major resection. Cirrhosis occurred in 62%. The mean operative time was 189.5 min, and the mean blood loss was 315.6 mL. Blood transfusion was required in 14.6% of patients. There were two operative deaths. Postoperative complications included bile leakage (1%), bleeding (2.9%), liver failure (5.1%), and ascites (6%). The 1-year, 3-year, and 5-year diseasefree survival rates ranged from 60% to 90%, 50% to 64%, and 31% to 50%, respectively, and the corresponding overall survival rates ranged from 85% to 100%, 67% to 100%, and 50% to 97% respectively. CONCLUSION: Laparoscopic liver resection for hepatocellular carcinoma appears to be safe and to achieve acceptable oncologic outcomes even in cirrhotic livers, but whether it is comparable to conventional open surgery needs to be evaluated in a randomized, controlled trial setting. © 2010 Asian Surgical Association.
 
ISSN1015-9584
2013 Impact Factor: 0.758
2013 SCImago Journal Rankings: 0.361
 
DOIhttp://dx.doi.org/10.1016/S1015-9584(11)60002-X
 
ISI Accession Number IDWOS:000288476100002
 
ReferencesReferences in Scopus
 
DC FieldValue
dc.contributor.authorChung, CD
 
dc.contributor.authorLau, LL
 
dc.contributor.authorKo, KL
 
dc.contributor.authorWong, AC
 
dc.contributor.authorWong, S
 
dc.contributor.authorChan, AC
 
dc.contributor.authorPoon, RT
 
dc.contributor.authorLo, CM
 
dc.contributor.authorFan, ST
 
dc.date.accessioned2011-07-27T01:36:47Z
 
dc.date.available2011-07-27T01:36:47Z
 
dc.date.issued2010
 
dc.description.abstractOBJECTIVE: To provide an updated review on the clinical experience in laparoscopic liver resection, specifically for hepatocellular carcinoma. METHODS: A comprehensive literature search in MEDLINE was conducted for all English papers up to May 2010 on laparoscopic liver resection for hepatocellular carcinoma. Patient characteristics, perioperative results, and oncologic outcomes were compared and analysed. RESULTS: We analysed 11 clinical studies involving 466 hepatocellular carcinoma patients treated with laparoscopic hepatectomy. Thirty-seven (9%) patients underwent major resection. Cirrhosis occurred in 62%. The mean operative time was 189.5 min, and the mean blood loss was 315.6 mL. Blood transfusion was required in 14.6% of patients. There were two operative deaths. Postoperative complications included bile leakage (1%), bleeding (2.9%), liver failure (5.1%), and ascites (6%). The 1-year, 3-year, and 5-year diseasefree survival rates ranged from 60% to 90%, 50% to 64%, and 31% to 50%, respectively, and the corresponding overall survival rates ranged from 85% to 100%, 67% to 100%, and 50% to 97% respectively. CONCLUSION: Laparoscopic liver resection for hepatocellular carcinoma appears to be safe and to achieve acceptable oncologic outcomes even in cirrhotic livers, but whether it is comparable to conventional open surgery needs to be evaluated in a randomized, controlled trial setting. © 2010 Asian Surgical Association.
 
dc.description.naturelink_to_subscribed_fulltext
 
dc.identifier.citationAsian Journal Of Surgery, 2010, v. 33 n. 4, p. 168-172 [How to Cite?]
DOI: http://dx.doi.org/10.1016/S1015-9584(11)60002-X
 
dc.identifier.doihttp://dx.doi.org/10.1016/S1015-9584(11)60002-X
 
dc.identifier.epage172
 
dc.identifier.hkuros187658
 
dc.identifier.hkuros234497
 
dc.identifier.isiWOS:000288476100002
 
dc.identifier.issn1015-9584
2013 Impact Factor: 0.758
2013 SCImago Journal Rankings: 0.361
 
dc.identifier.issue4
 
dc.identifier.openurl
 
dc.identifier.pmid21377102
 
dc.identifier.scopuseid_2-s2.0-79952382942
 
dc.identifier.spage168
 
dc.identifier.urihttp://hdl.handle.net/10722/135542
 
dc.identifier.volume33
 
dc.languageeng
 
dc.publisherElsevier (Singapore) Pte Ltd, Hong Kong Branch. The Journal's web site is located at http://www.elsevier.com/wps/find/journaldescription.cws_home/708511/description#description
 
dc.publisher.placeHong Kong
 
dc.relation.ispartofAsian Journal of Surgery
 
dc.relation.referencesReferences in Scopus
 
dc.subject.meshCarcinoma, Hepatocellular - mortality - surgery
 
dc.subject.meshDisease-Free Survival
 
dc.subject.meshHepatectomy - statistics and numerical data
 
dc.subject.meshLaparoscopy - statistics and numerical data
 
dc.subject.meshLiver Neoplasms - mortality - surgery
 
dc.subjecthepatocellular carcinoma
 
dc.subjectlaparoscopic liver resection
 
dc.titleLaparoscopic liver resection for hepatocellular carcinoma
 
dc.typeArticle
 
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<item><contributor.author>Chung, CD</contributor.author>
<contributor.author>Lau, LL</contributor.author>
<contributor.author>Ko, KL</contributor.author>
<contributor.author>Wong, AC</contributor.author>
<contributor.author>Wong, S</contributor.author>
<contributor.author>Chan, AC</contributor.author>
<contributor.author>Poon, RT</contributor.author>
<contributor.author>Lo, CM</contributor.author>
<contributor.author>Fan, ST</contributor.author>
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<description.abstract>OBJECTIVE: To provide an updated review on the clinical experience in laparoscopic liver resection, specifically for hepatocellular carcinoma. METHODS: A comprehensive literature search in MEDLINE was conducted for all English papers up to May 2010 on laparoscopic liver resection for hepatocellular carcinoma. Patient characteristics, perioperative results, and oncologic outcomes were compared and analysed. RESULTS: We analysed 11 clinical studies involving 466 hepatocellular carcinoma patients treated with laparoscopic hepatectomy. Thirty-seven (9%) patients underwent major resection. Cirrhosis occurred in 62%. The mean operative time was 189.5 min, and the mean blood loss was 315.6 mL. Blood transfusion was required in 14.6% of patients. There were two operative deaths. Postoperative complications included bile leakage (1%), bleeding (2.9%), liver failure (5.1%), and ascites (6%). The 1-year, 3-year, and 5-year diseasefree survival rates ranged from 60% to 90%, 50% to 64%, and 31% to 50%, respectively, and the corresponding overall survival rates ranged from 85% to 100%, 67% to 100%, and 50% to 97% respectively. CONCLUSION: Laparoscopic liver resection for hepatocellular carcinoma appears to be safe and to achieve acceptable oncologic outcomes even in cirrhotic livers, but whether it is comparable to conventional open surgery needs to be evaluated in a randomized, controlled trial setting. &#169; 2010 Asian Surgical Association.</description.abstract>
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Author Affiliations
  1. The University of Hong Kong
  2. Queen Mary Hospital Hong Kong