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Article: Role of stem cells in normal liver and cancer

TitleRole of stem cells in normal liver and cancer
Authors
KeywordsCancer stem cells
Hepatocellular carcinoma
Normal stem cells
Issue Date2011
PublisherBentham Science Publishers Ltd. The Journal's web site is located at http://www.bentham.org/cmcaca
Citation
Anti-Cancer Agents In Medicinal Chemistry, 2011, v. 11 n. 6, p. 522-528 How to Cite?
AbstractHepatocellular carcinoma (HCC) is the third most common cause of cancer-related mortality in the world because current treatments, including both surgical and non-surgical ones, cannot effectively cure this disease. Increasing evidence has revealed the importance of cancer stem cells (CSCs) in hepatocarcinogenesis, and the idea of targeting CSCs sheds light on more effective therapeutic strategies for HCC. In this review, normal stem cells and putative CSCs in the liver are briefly introduced. Studies about signaling pathways that regulate pathophysiological activities of liver CSCs and the therapeutic potential by targeting CSCs are also summarized and discussed. © 2011 Bentham Science Publishers Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/135526
ISSN
2015 Impact Factor: 2.722
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLau, CKen_HK
dc.contributor.authorYang, ZFen_HK
dc.contributor.authorFan, STen_HK
dc.date.accessioned2011-07-27T01:36:32Z-
dc.date.available2011-07-27T01:36:32Z-
dc.date.issued2011en_HK
dc.identifier.citationAnti-Cancer Agents In Medicinal Chemistry, 2011, v. 11 n. 6, p. 522-528en_HK
dc.identifier.issn1871-5206en_HK
dc.identifier.urihttp://hdl.handle.net/10722/135526-
dc.description.abstractHepatocellular carcinoma (HCC) is the third most common cause of cancer-related mortality in the world because current treatments, including both surgical and non-surgical ones, cannot effectively cure this disease. Increasing evidence has revealed the importance of cancer stem cells (CSCs) in hepatocarcinogenesis, and the idea of targeting CSCs sheds light on more effective therapeutic strategies for HCC. In this review, normal stem cells and putative CSCs in the liver are briefly introduced. Studies about signaling pathways that regulate pathophysiological activities of liver CSCs and the therapeutic potential by targeting CSCs are also summarized and discussed. © 2011 Bentham Science Publishers Ltd.en_HK
dc.languageengen_US
dc.publisherBentham Science Publishers Ltd. The Journal's web site is located at http://www.bentham.org/cmcacaen_HK
dc.relation.ispartofAnti-Cancer Agents in Medicinal Chemistryen_HK
dc.subjectCancer stem cellsen_HK
dc.subjectHepatocellular carcinomaen_HK
dc.subjectNormal stem cellsen_HK
dc.titleRole of stem cells in normal liver and canceren_HK
dc.typeArticleen_HK
dc.identifier.emailFan, ST: stfan@hku.hken_HK
dc.identifier.authorityFan, ST=rp00355en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.pmid21554200-
dc.identifier.scopuseid_2-s2.0-79959321260en_HK
dc.identifier.hkuros187502en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-79959321260&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume11en_HK
dc.identifier.issue6en_HK
dc.identifier.spage522en_HK
dc.identifier.epage528en_HK
dc.identifier.isiWOS:000292761600004-
dc.publisher.placeNetherlandsen_HK
dc.identifier.scopusauthoridLau, CK=7401968442en_HK
dc.identifier.scopusauthoridYang, ZF=39863860200en_HK
dc.identifier.scopusauthoridFan, ST=7402678224en_HK

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