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- Scopus: eid_2-s2.0-79959321260
- PMID: 21554200
- WOS: WOS:000292761600004
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Article: Role of stem cells in normal liver and cancer
Title | Role of stem cells in normal liver and cancer |
---|---|
Authors | |
Keywords | Cancer stem cells Hepatocellular carcinoma Normal stem cells |
Issue Date | 2011 |
Publisher | Bentham Science Publishers Ltd. The Journal's web site is located at http://www.bentham.org/cmcaca |
Citation | Anti-Cancer Agents In Medicinal Chemistry, 2011, v. 11 n. 6, p. 522-528 How to Cite? |
Abstract | Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related mortality in the world because current treatments, including both surgical and non-surgical ones, cannot effectively cure this disease. Increasing evidence has revealed the importance of cancer stem cells (CSCs) in hepatocarcinogenesis, and the idea of targeting CSCs sheds light on more effective therapeutic strategies for HCC. In this review, normal stem cells and putative CSCs in the liver are briefly introduced. Studies about signaling pathways that regulate pathophysiological activities of liver CSCs and the therapeutic potential by targeting CSCs are also summarized and discussed. © 2011 Bentham Science Publishers Ltd. |
Persistent Identifier | http://hdl.handle.net/10722/135526 |
ISSN | 2023 Impact Factor: 2.6 2023 SCImago Journal Rankings: 0.503 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lau, CK | en_HK |
dc.contributor.author | Yang, ZF | en_HK |
dc.contributor.author | Fan, ST | en_HK |
dc.date.accessioned | 2011-07-27T01:36:32Z | - |
dc.date.available | 2011-07-27T01:36:32Z | - |
dc.date.issued | 2011 | en_HK |
dc.identifier.citation | Anti-Cancer Agents In Medicinal Chemistry, 2011, v. 11 n. 6, p. 522-528 | en_HK |
dc.identifier.issn | 1871-5206 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/135526 | - |
dc.description.abstract | Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related mortality in the world because current treatments, including both surgical and non-surgical ones, cannot effectively cure this disease. Increasing evidence has revealed the importance of cancer stem cells (CSCs) in hepatocarcinogenesis, and the idea of targeting CSCs sheds light on more effective therapeutic strategies for HCC. In this review, normal stem cells and putative CSCs in the liver are briefly introduced. Studies about signaling pathways that regulate pathophysiological activities of liver CSCs and the therapeutic potential by targeting CSCs are also summarized and discussed. © 2011 Bentham Science Publishers Ltd. | en_HK |
dc.language | eng | en_US |
dc.publisher | Bentham Science Publishers Ltd. The Journal's web site is located at http://www.bentham.org/cmcaca | en_HK |
dc.relation.ispartof | Anti-Cancer Agents in Medicinal Chemistry | en_HK |
dc.subject | Cancer stem cells | en_HK |
dc.subject | Hepatocellular carcinoma | en_HK |
dc.subject | Normal stem cells | en_HK |
dc.title | Role of stem cells in normal liver and cancer | en_HK |
dc.type | Article | en_HK |
dc.identifier.email | Fan, ST: stfan@hku.hk | en_HK |
dc.identifier.authority | Fan, ST=rp00355 | en_HK |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.pmid | 21554200 | - |
dc.identifier.scopus | eid_2-s2.0-79959321260 | en_HK |
dc.identifier.hkuros | 187502 | en_US |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-79959321260&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 11 | en_HK |
dc.identifier.issue | 6 | en_HK |
dc.identifier.spage | 522 | en_HK |
dc.identifier.epage | 528 | en_HK |
dc.identifier.isi | WOS:000292761600004 | - |
dc.publisher.place | Netherlands | en_HK |
dc.identifier.scopusauthorid | Lau, CK=7401968442 | en_HK |
dc.identifier.scopusauthorid | Yang, ZF=39863860200 | en_HK |
dc.identifier.scopusauthorid | Fan, ST=7402678224 | en_HK |
dc.identifier.issnl | 1871-5206 | - |