Article: Studying the transmission dynamics of meticillin-resistant Staphylococcus aureus in Hong Kong using spa typing

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TitleStudying the transmission dynamics of meticillin-resistant Staphylococcus aureus in Hong Kong using spa typing
AuthorsCheng, VCC
Chan, JFW
Lau, EHY
Yam, WC
Ho, SKY
Yau, MCY
Tse, EYF
Wong, ACY
Tai, JWM
Fan, ST
Ho, PL
Yuen, KY
KeywordsMeticillin-resistant Staphylococcus aureus
Nosocomial transmission
Spa type
Transmissibility
Transmission dynamics
Issue Date2011
PublisherWB Saunders Co Ltd. The Journal's web site is located at http://www.elsevier.com/locate/jhin
CitationJournal Of Hospital Infection, 2011, v. 79 n. 3, p. 206-210 [How to Cite?]
DOI: http://dx.doi.org/10.1016/j.jhin.2011.03.024
AbstractThis study investigated the transmission dynamics of meticillin-resistant Staphylococcus aureus (MRSA) in a tertiary referral surgical unit with 300 beds. All adult patients were actively screened for MRSA by culture at hospital admission and twice weekly thereafter during hospitalisation from 1 October to 31 December 2008. The colonisation pressure per 1000 patient-days and the incidence density of nosocomial MRSA transmission per 1000 colonisation-days were calculated for the different spa types of MRSA. In total, 6619 nasal swabs were obtained from 2289 patients. One-hundred and forty-eight (7%) patients had MRSA in nasal swabs at admission screening, of which 68/148 (46%) were residents of elderly care homes. Fifty-two of 2141 (2%) patients had conversion of nasal MRSA carriage status from negative to positive during hospitalisation. Among the 200 patients with MRSA, spa types t1081 and t037 were found in 99 (50%) and 30 (15%) patients, respectively. The colonisation pressure per 1000 patient-days was 40.9 for t0181, 22.2 for t037 and 26.3 for the less common spa types. The incidence densities of nosocomial MRSA transmission per 1000 colonisation-days were significantly higher for t1081 (28.5 vs 4.0, P< 0.01) and t037 (21.5 vs 4.0, P= 0.03) compared with the less common spa types. Proactive screening of MRSA in patients from elderly care homes and targeted isolation of these patients, especially those carrying spa types with high transmissibility, are important for the control of MRSA in hospitals. © 2011 The Healthcare Infection Society.
ISSN0195-6701
2011 Impact Factor: 3.393
2011 SCImago Journal Rankings: 0.256
DOIhttp://dx.doi.org/10.1016/j.jhin.2011.03.024
ISI Accession Number IDWOS:000296152600005
Funding AgencyGrant Number
Food and Health Bureau of the Hong Kong SAR Government
Funding Information:

The work was supported by the Research Fund for the Control of Infectious Diseases of the Food and Health Bureau of the Hong Kong SAR Government.

ReferencesReferences in Scopus
DC Field
Value
dc.contributor.authorCheng, VCC
dc.contributor.authorChan, JFW
dc.contributor.authorLau, EHY
dc.contributor.authorYam, WC
dc.contributor.authorHo, SKY
dc.contributor.authorYau, MCY
dc.contributor.authorTse, EYF
dc.contributor.authorWong, ACY
dc.contributor.authorTai, JWM
dc.contributor.authorFan, ST
dc.contributor.authorHo, PL
dc.contributor.authorYuen, KY
dc.date.accessioned2011-07-27T01:36:30Z
dc.date.available2011-07-27T01:36:30Z
dc.date.issued2011
dc.description.abstractThis study investigated the transmission dynamics of meticillin-resistant Staphylococcus aureus (MRSA) in a tertiary referral surgical unit with 300 beds. All adult patients were actively screened for MRSA by culture at hospital admission and twice weekly thereafter during hospitalisation from 1 October to 31 December 2008. The colonisation pressure per 1000 patient-days and the incidence density of nosocomial MRSA transmission per 1000 colonisation-days were calculated for the different spa types of MRSA. In total, 6619 nasal swabs were obtained from 2289 patients. One-hundred and forty-eight (7%) patients had MRSA in nasal swabs at admission screening, of which 68/148 (46%) were residents of elderly care homes. Fifty-two of 2141 (2%) patients had conversion of nasal MRSA carriage status from negative to positive during hospitalisation. Among the 200 patients with MRSA, spa types t1081 and t037 were found in 99 (50%) and 30 (15%) patients, respectively. The colonisation pressure per 1000 patient-days was 40.9 for t0181, 22.2 for t037 and 26.3 for the less common spa types. The incidence densities of nosocomial MRSA transmission per 1000 colonisation-days were significantly higher for t1081 (28.5 vs 4.0, P< 0.01) and t037 (21.5 vs 4.0, P= 0.03) compared with the less common spa types. Proactive screening of MRSA in patients from elderly care homes and targeted isolation of these patients, especially those carrying spa types with high transmissibility, are important for the control of MRSA in hospitals. © 2011 The Healthcare Infection Society.
dc.description.natureLink_to_subscribed_fulltext
dc.identifier.citationJournal Of Hospital Infection, 2011, v. 79 n. 3, p. 206-210 [How to Cite?]
DOI: http://dx.doi.org/10.1016/j.jhin.2011.03.024
dc.identifier.doihttp://dx.doi.org/10.1016/j.jhin.2011.03.024
dc.identifier.epage210
dc.identifier.hkuros187495
dc.identifier.isiWOS:000296152600005
Funding AgencyGrant Number
Food and Health Bureau of the Hong Kong SAR Government
Funding Information:

The work was supported by the Research Fund for the Control of Infectious Diseases of the Food and Health Bureau of the Hong Kong SAR Government.

dc.identifier.issn0195-6701
2011 Impact Factor: 3.393
2011 SCImago Journal Rankings: 0.256
dc.identifier.issue3
dc.identifier.openurl
dc.identifier.pmid21641082
dc.identifier.scopuseid_2-s2.0-80053305859
dc.identifier.spage206
dc.identifier.urihttp://hdl.handle.net/10722/135524
dc.identifier.volume79
dc.languageeng
dc.publisherWB Saunders Co Ltd. The Journal's web site is located at http://www.elsevier.com/locate/jhin
dc.publisher.placeUnited Kingdom
dc.relation.ispartofJournal of Hospital Infection
dc.relation.referencesReferences in Scopus
dc.subjectMeticillin-resistant Staphylococcus aureus
dc.subjectNosocomial transmission
dc.subjectSpa type
dc.subjectTransmissibility
dc.subjectTransmission dynamics
dc.titleStudying the transmission dynamics of meticillin-resistant Staphylococcus aureus in Hong Kong using spa typing
dc.typeArticle
Author Affiliations
  1. The University of Hong Kong
  2. Queen Mary Hospital Hong Kong