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Article: Studying the transmission dynamics of meticillin-resistant Staphylococcus aureus in Hong Kong using spa typing
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TitleStudying the transmission dynamics of meticillin-resistant Staphylococcus aureus in Hong Kong using spa typing
 
AuthorsCheng, VCC2
Chan, JFW2
Lau, EHY1
Yam, WC2 1
Ho, SKY2
Yau, MCY2
Tse, EYF2
Wong, ACY2
Tai, JWM2
Fan, ST2
Ho, PL2 1
Yuen, KY2 1
 
KeywordsMeticillin-resistant Staphylococcus aureus
Nosocomial transmission
Spa type
Transmissibility
Transmission dynamics
 
Issue Date2011
 
PublisherWB Saunders Co Ltd. The Journal's web site is located at http://www.elsevier.com/locate/jhin
 
CitationJournal Of Hospital Infection, 2011, v. 79 n. 3, p. 206-210 [How to Cite?]
DOI: http://dx.doi.org/10.1016/j.jhin.2011.03.024
 
AbstractThis study investigated the transmission dynamics of meticillin-resistant Staphylococcus aureus (MRSA) in a tertiary referral surgical unit with 300 beds. All adult patients were actively screened for MRSA by culture at hospital admission and twice weekly thereafter during hospitalisation from 1 October to 31 December 2008. The colonisation pressure per 1000 patient-days and the incidence density of nosocomial MRSA transmission per 1000 colonisation-days were calculated for the different spa types of MRSA. In total, 6619 nasal swabs were obtained from 2289 patients. One-hundred and forty-eight (7%) patients had MRSA in nasal swabs at admission screening, of which 68/148 (46%) were residents of elderly care homes. Fifty-two of 2141 (2%) patients had conversion of nasal MRSA carriage status from negative to positive during hospitalisation. Among the 200 patients with MRSA, spa types t1081 and t037 were found in 99 (50%) and 30 (15%) patients, respectively. The colonisation pressure per 1000 patient-days was 40.9 for t0181, 22.2 for t037 and 26.3 for the less common spa types. The incidence densities of nosocomial MRSA transmission per 1000 colonisation-days were significantly higher for t1081 (28.5 vs 4.0, P< 0.01) and t037 (21.5 vs 4.0, P= 0.03) compared with the less common spa types. Proactive screening of MRSA in patients from elderly care homes and targeted isolation of these patients, especially those carrying spa types with high transmissibility, are important for the control of MRSA in hospitals. © 2011 The Healthcare Infection Society.
 
ISSN0195-6701
2013 Impact Factor: 2.782
2013 SCImago Journal Rankings: 1.355
 
DOIhttp://dx.doi.org/10.1016/j.jhin.2011.03.024
 
ISI Accession Number IDWOS:000296152600005
Funding AgencyGrant Number
Food and Health Bureau of the Hong Kong SAR Government
Funding Information:

The work was supported by the Research Fund for the Control of Infectious Diseases of the Food and Health Bureau of the Hong Kong SAR Government.

 
ReferencesReferences in Scopus
 
DC FieldValue
dc.contributor.authorCheng, VCC
 
dc.contributor.authorChan, JFW
 
dc.contributor.authorLau, EHY
 
dc.contributor.authorYam, WC
 
dc.contributor.authorHo, SKY
 
dc.contributor.authorYau, MCY
 
dc.contributor.authorTse, EYF
 
dc.contributor.authorWong, ACY
 
dc.contributor.authorTai, JWM
 
dc.contributor.authorFan, ST
 
dc.contributor.authorHo, PL
 
dc.contributor.authorYuen, KY
 
dc.date.accessioned2011-07-27T01:36:30Z
 
dc.date.available2011-07-27T01:36:30Z
 
dc.date.issued2011
 
dc.description.abstractThis study investigated the transmission dynamics of meticillin-resistant Staphylococcus aureus (MRSA) in a tertiary referral surgical unit with 300 beds. All adult patients were actively screened for MRSA by culture at hospital admission and twice weekly thereafter during hospitalisation from 1 October to 31 December 2008. The colonisation pressure per 1000 patient-days and the incidence density of nosocomial MRSA transmission per 1000 colonisation-days were calculated for the different spa types of MRSA. In total, 6619 nasal swabs were obtained from 2289 patients. One-hundred and forty-eight (7%) patients had MRSA in nasal swabs at admission screening, of which 68/148 (46%) were residents of elderly care homes. Fifty-two of 2141 (2%) patients had conversion of nasal MRSA carriage status from negative to positive during hospitalisation. Among the 200 patients with MRSA, spa types t1081 and t037 were found in 99 (50%) and 30 (15%) patients, respectively. The colonisation pressure per 1000 patient-days was 40.9 for t0181, 22.2 for t037 and 26.3 for the less common spa types. The incidence densities of nosocomial MRSA transmission per 1000 colonisation-days were significantly higher for t1081 (28.5 vs 4.0, P< 0.01) and t037 (21.5 vs 4.0, P= 0.03) compared with the less common spa types. Proactive screening of MRSA in patients from elderly care homes and targeted isolation of these patients, especially those carrying spa types with high transmissibility, are important for the control of MRSA in hospitals. © 2011 The Healthcare Infection Society.
 
dc.description.natureLink_to_subscribed_fulltext
 
dc.identifier.citationJournal Of Hospital Infection, 2011, v. 79 n. 3, p. 206-210 [How to Cite?]
DOI: http://dx.doi.org/10.1016/j.jhin.2011.03.024
 
dc.identifier.doihttp://dx.doi.org/10.1016/j.jhin.2011.03.024
 
dc.identifier.epage210
 
dc.identifier.hkuros187495
 
dc.identifier.isiWOS:000296152600005
Funding AgencyGrant Number
Food and Health Bureau of the Hong Kong SAR Government
Funding Information:

The work was supported by the Research Fund for the Control of Infectious Diseases of the Food and Health Bureau of the Hong Kong SAR Government.

 
dc.identifier.issn0195-6701
2013 Impact Factor: 2.782
2013 SCImago Journal Rankings: 1.355
 
dc.identifier.issue3
 
dc.identifier.openurl
 
dc.identifier.pmid21641082
 
dc.identifier.scopuseid_2-s2.0-80053305859
 
dc.identifier.spage206
 
dc.identifier.urihttp://hdl.handle.net/10722/135524
 
dc.identifier.volume79
 
dc.languageeng
 
dc.publisherWB Saunders Co Ltd. The Journal's web site is located at http://www.elsevier.com/locate/jhin
 
dc.publisher.placeUnited Kingdom
 
dc.relation.ispartofJournal of Hospital Infection
 
dc.relation.referencesReferences in Scopus
 
dc.subjectMeticillin-resistant Staphylococcus aureus
 
dc.subjectNosocomial transmission
 
dc.subjectSpa type
 
dc.subjectTransmissibility
 
dc.subjectTransmission dynamics
 
dc.titleStudying the transmission dynamics of meticillin-resistant Staphylococcus aureus in Hong Kong using spa typing
 
dc.typeArticle
 
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Author Affiliations
  1. The University of Hong Kong
  2. Queen Mary Hospital Hong Kong