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Article: Ethnic differences in cardiovascular risk in rheumatic disease: Focus on Asians

TitleEthnic differences in cardiovascular risk in rheumatic disease: Focus on Asians
Authors
Issue Date2011
PublisherNature Publishing Group. The Journal's web site is located at http://www.nature.com/nrrheum/index.html
Citation
Nature Reviews Rheumatology, 2011, v. 7 n. 10, p. 609-618 How to Cite?
AbstractRheumatic diseases are associated with high cardiovascular morbidity and mortality. Considerable differences exist in the frequency of cardiovascular disease (CVD) risk factors and events among people of different ethnic origins, but little is known of the ethnic variations in the relative distribution of CVD risk factors and the degree of atherosclerosis in patients with rheumatic diseases. Understanding this variation will provide insight into the underlying pathogenesis of CVD in patients with rheumatic diseases, and aid in future studies of the detection and management of this complication. In general, although Asian patients seem to have fewer background CVD risk factors and are less affected by metabolic syndrome (MetS) than their non-Asian counterparts, those with rheumatic disease are equally as susceptible to CVD. Furthermore, it seems that systemic inflammation and mechanisms that do not involve conventional CVD risk factors and MetS have an important role in the development of atherosclerosis in patients with rheumatic diseases. Here we examine the frequency of conventional CVD risk factors and the prevalence of MetS in both Asian and non-Asian patients with selected rheumatic diseases. We also discuss the burden of CVD, as evaluated using various surrogate markers in these patients, and their overall CVD mortality rate. © 2011 Macmillan Publishers Limited. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/135235
ISSN
2015 Impact Factor: 10.531
2015 SCImago Journal Rankings: 2.728
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorYiu, KHen_HK
dc.contributor.authorTse, HFen_HK
dc.contributor.authorMok, MYen_HK
dc.contributor.authorLau, CSen_HK
dc.date.accessioned2011-07-27T01:30:23Z-
dc.date.available2011-07-27T01:30:23Z-
dc.date.issued2011en_HK
dc.identifier.citationNature Reviews Rheumatology, 2011, v. 7 n. 10, p. 609-618en_HK
dc.identifier.issn1759-4790en_HK
dc.identifier.urihttp://hdl.handle.net/10722/135235-
dc.description.abstractRheumatic diseases are associated with high cardiovascular morbidity and mortality. Considerable differences exist in the frequency of cardiovascular disease (CVD) risk factors and events among people of different ethnic origins, but little is known of the ethnic variations in the relative distribution of CVD risk factors and the degree of atherosclerosis in patients with rheumatic diseases. Understanding this variation will provide insight into the underlying pathogenesis of CVD in patients with rheumatic diseases, and aid in future studies of the detection and management of this complication. In general, although Asian patients seem to have fewer background CVD risk factors and are less affected by metabolic syndrome (MetS) than their non-Asian counterparts, those with rheumatic disease are equally as susceptible to CVD. Furthermore, it seems that systemic inflammation and mechanisms that do not involve conventional CVD risk factors and MetS have an important role in the development of atherosclerosis in patients with rheumatic diseases. Here we examine the frequency of conventional CVD risk factors and the prevalence of MetS in both Asian and non-Asian patients with selected rheumatic diseases. We also discuss the burden of CVD, as evaluated using various surrogate markers in these patients, and their overall CVD mortality rate. © 2011 Macmillan Publishers Limited. All rights reserved.en_HK
dc.languageengen_US
dc.publisherNature Publishing Group. The Journal's web site is located at http://www.nature.com/nrrheum/index.htmlen_HK
dc.relation.ispartofNature Reviews Rheumatologyen_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subject.meshAsian Continental Ancestry Group-
dc.subject.meshBiological Markers-
dc.subject.meshCardiovascular Diseases - ethnology - etiology-
dc.subject.meshMetabolic Syndrome X - complications - ethnology-
dc.subject.meshRheumatic Diseases - complications - ethnology-
dc.titleEthnic differences in cardiovascular risk in rheumatic disease: Focus on Asiansen_HK
dc.typeArticleen_HK
dc.identifier.emailYiu, KH:khkyiu@hku.hken_HK
dc.identifier.emailTse, HF:hftse@hkucc.hku.hken_HK
dc.identifier.emailMok, MY:temy@hkucc.hku.hken_HK
dc.identifier.emailLau, CS:cslau@hku.hken_HK
dc.identifier.authorityYiu, KH=rp01490en_HK
dc.identifier.authorityTse, HF=rp00428en_HK
dc.identifier.authorityMok, MY=rp00490en_HK
dc.identifier.authorityLau, CS=rp01348en_HK
dc.description.naturepostprint-
dc.identifier.doi10.1038/nrrheum.2011.126en_HK
dc.identifier.pmid21912432-
dc.identifier.scopuseid_2-s2.0-80053913306en_HK
dc.identifier.hkuros187314en_US
dc.identifier.hkuros201290-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-80053913306&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume7en_HK
dc.identifier.issue10en_HK
dc.identifier.spage609en_HK
dc.identifier.epage618en_HK
dc.identifier.isiWOS:000295625600009-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridYiu, KH=35172267800en_HK
dc.identifier.scopusauthoridTse, HF=7006070805en_HK
dc.identifier.scopusauthoridMok, MY=7006024184en_HK
dc.identifier.scopusauthoridLau, CS=14035682100en_HK

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