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Article: Long-term clinical implication of the occurrence of dissociated pulmonary vein activities after circumferential left atrial ablation in patients with paroxysmal atrial fibrillation.
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TitleLong-term clinical implication of the occurrence of dissociated pulmonary vein activities after circumferential left atrial ablation in patients with paroxysmal atrial fibrillation.
 
AuthorsChen, H2
Yang, B2
Ju, W2
Zhang, F2
Hou, X2
Chen, C2
Zhai, L2
Wang, J2
Cao, K2
Chen, M2
Tse, HF1 3
 
KeywordsCatheter ablation
Paroxysmal atrial fibrillation
Pulmonary vein isolation
 
Issue Date2010
 
PublisherJapanese Circulation Society. The Journal's web site is located at http://www.j-circ.or.jp/english/publications/
 
CitationCirculation Journal : Official Journal Of The Japanese Circulation Society, 2010, v. 75 n. 1, p. 73-79 [How to Cite?]
DOI: http://dx.doi.org/10.1253/circj.CJ-10-0434
 
AbstractThe incidence and clinical implication of dissociated pulmonary vein (PV) electrical activities after circumferential antrum PV ablation for paroxysmal atrial fibrillation (AF) remains unclear. A total of 196 patients with symptomatic paroxysmal AF who underwent circumferential antrum PV ablation were prospectively studied. Dissociated PV electrical activities were observed in 101 patients (Group 1), but absent in the remaining 95 patients (Group 2). There were no significant differences in the baseline clinical characteristics between them, except that Group 2 had a higher prevalence of hypertension (30 vs. 44%, P = 0.04). After 21.8 ± 7.9 months of follow-up, 148 had no recurrence of AF after the initial procedure. AF recurrence rate was significantly higher in Group 2 than in Group 1 (P = 0.023). Relapse of PV conduction was the major cause of AF recurrence in both groups (16/16 vs. 19/23, P = 0.08), and the overall procedural success rate after the redo ablation procedure was similar in the 2 groups (90 vs. 86%, P = 0.44). However, the total number of patients with non-PV foci was significantly higher in Group 2 than in Group 1 (12/95 vs. 2/101, P < 0.01). Dissociated PV electrical activities might identify a subgroup of patients with relatively higher initial procedural success with circumferential PV antrum ablation.
 
ISSN1347-4820
2012 SCImago Journal Rankings: 1.337
 
DOIhttp://dx.doi.org/10.1253/circj.CJ-10-0434
 
ISI Accession Number IDWOS:000285814300014
Funding AgencyGrant Number
Provincial Natural Science of Jiangsu, ChinaBK2005218
Funding Information:

This work was supported by a grant from Provincial Natural Science of Jiangsu, China (BK2005218).

 
DC FieldValue
dc.contributor.authorChen, H
 
dc.contributor.authorYang, B
 
dc.contributor.authorJu, W
 
dc.contributor.authorZhang, F
 
dc.contributor.authorHou, X
 
dc.contributor.authorChen, C
 
dc.contributor.authorZhai, L
 
dc.contributor.authorWang, J
 
dc.contributor.authorCao, K
 
dc.contributor.authorChen, M
 
dc.contributor.authorTse, HF
 
dc.date.accessioned2011-07-27T01:30:15Z
 
dc.date.available2011-07-27T01:30:15Z
 
dc.date.issued2010
 
dc.description.abstractThe incidence and clinical implication of dissociated pulmonary vein (PV) electrical activities after circumferential antrum PV ablation for paroxysmal atrial fibrillation (AF) remains unclear. A total of 196 patients with symptomatic paroxysmal AF who underwent circumferential antrum PV ablation were prospectively studied. Dissociated PV electrical activities were observed in 101 patients (Group 1), but absent in the remaining 95 patients (Group 2). There were no significant differences in the baseline clinical characteristics between them, except that Group 2 had a higher prevalence of hypertension (30 vs. 44%, P = 0.04). After 21.8 ± 7.9 months of follow-up, 148 had no recurrence of AF after the initial procedure. AF recurrence rate was significantly higher in Group 2 than in Group 1 (P = 0.023). Relapse of PV conduction was the major cause of AF recurrence in both groups (16/16 vs. 19/23, P = 0.08), and the overall procedural success rate after the redo ablation procedure was similar in the 2 groups (90 vs. 86%, P = 0.44). However, the total number of patients with non-PV foci was significantly higher in Group 2 than in Group 1 (12/95 vs. 2/101, P < 0.01). Dissociated PV electrical activities might identify a subgroup of patients with relatively higher initial procedural success with circumferential PV antrum ablation.
 
dc.description.naturelink_to_OA_fulltext
 
dc.identifier.citationCirculation Journal : Official Journal Of The Japanese Circulation Society, 2010, v. 75 n. 1, p. 73-79 [How to Cite?]
DOI: http://dx.doi.org/10.1253/circj.CJ-10-0434
 
dc.identifier.doihttp://dx.doi.org/10.1253/circj.CJ-10-0434
 
dc.identifier.epage79
 
dc.identifier.hkuros187302
 
dc.identifier.isiWOS:000285814300014
Funding AgencyGrant Number
Provincial Natural Science of Jiangsu, ChinaBK2005218
Funding Information:

This work was supported by a grant from Provincial Natural Science of Jiangsu, China (BK2005218).

 
dc.identifier.issn1347-4820
2012 SCImago Journal Rankings: 1.337
 
dc.identifier.issue1
 
dc.identifier.pmid21071875
 
dc.identifier.scopuseid_2-s2.0-79952277712
 
dc.identifier.scopuseid_2-s2.0-78651228411
 
dc.identifier.spage73
 
dc.identifier.urihttp://hdl.handle.net/10722/135224
 
dc.identifier.volume75
 
dc.languageeng
 
dc.publisherJapanese Circulation Society. The Journal's web site is located at http://www.j-circ.or.jp/english/publications/
 
dc.publisher.placeJapan
 
dc.relation.ispartofCirculation journal : official journal of the Japanese Circulation Society
 
dc.subject.meshAtrial Fibrillation - physiopathology - surgery
 
dc.subject.meshCatheter Ablation
 
dc.subject.meshElectrophysiologic Techniques, Cardiac
 
dc.subject.meshPulmonary Veins - physiopathology - surgery
 
dc.subject.meshRisk Assessment
 
dc.subjectCatheter ablation
 
dc.subjectParoxysmal atrial fibrillation
 
dc.subjectPulmonary vein isolation
 
dc.titleLong-term clinical implication of the occurrence of dissociated pulmonary vein activities after circumferential left atrial ablation in patients with paroxysmal atrial fibrillation.
 
dc.typeArticle
 
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<item><contributor.author>Chen, H</contributor.author>
<contributor.author>Yang, B</contributor.author>
<contributor.author>Ju, W</contributor.author>
<contributor.author>Zhang, F</contributor.author>
<contributor.author>Hou, X</contributor.author>
<contributor.author>Chen, C</contributor.author>
<contributor.author>Zhai, L</contributor.author>
<contributor.author>Wang, J</contributor.author>
<contributor.author>Cao, K</contributor.author>
<contributor.author>Chen, M</contributor.author>
<contributor.author>Tse, HF</contributor.author>
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<description.abstract>The incidence and clinical implication of dissociated pulmonary vein (PV) electrical activities after circumferential antrum PV ablation for paroxysmal atrial fibrillation (AF) remains unclear. A total of 196 patients with symptomatic paroxysmal AF who underwent circumferential antrum PV ablation were prospectively studied. Dissociated PV electrical activities were observed in 101 patients (Group 1), but absent in the remaining 95 patients (Group 2). There were no significant differences in the baseline clinical characteristics between them, except that Group 2 had a higher prevalence of hypertension (30 vs. 44%, P = 0.04). After 21.8 &#177; 7.9 months of follow-up, 148 had no recurrence of AF after the initial procedure. AF recurrence rate was significantly higher in Group 2 than in Group 1 (P = 0.023). Relapse of PV conduction was the major cause of AF recurrence in both groups (16/16 vs. 19/23, P = 0.08), and the overall procedural success rate after the redo ablation procedure was similar in the 2 groups (90 vs. 86%, P = 0.44). However, the total number of patients with non-PV foci was significantly higher in Group 2 than in Group 1 (12/95 vs. 2/101, P &lt; 0.01). Dissociated PV electrical activities might identify a subgroup of patients with relatively higher initial procedural success with circumferential PV antrum ablation.</description.abstract>
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<subject>Catheter ablation</subject>
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Author Affiliations
  1. Hospital of Nanjing Medical University