File Download
  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Evaluation of next-generation sequencing software in mapping and assembly

TitleEvaluation of next-generation sequencing software in mapping and assembly
Authors
Issue Date2011
PublisherSpringer Japan. The Journal's web site is located at http://link.springer.de/link/service/journals/10038/index.htm
Citation
Journal of Human Genetics, 2011, v. 56 n. 6, p. 406-414 How to Cite?
AbstractNext-generation high-throughput DNA sequencing technologies have advanced progressively in sequence-based genomic research and novel biological applications with the promise of sequencing DNA at unprecedented speed. These new non-Sanger-based technologies feature several advantages when compared with traditional sequencing methods in terms of higher sequencing speed, lower per run cost and higher accuracy. However, reads from next-generation sequencing (NGS) platforms, such as 454/Roche, ABI/SOLiD and Illumina/Solexa, are usually short, thereby restricting the applications of NGS platforms in genome assembly and annotation. We presented an overview of the challenges that these novel technologies meet and particularly illustrated various bioinformatics attempts on mapping and assembly for problem solving. We then compared the performance of several programs in these two fields, and further provided advices on selecting suitable tools for specific biological applications.
Persistent Identifierhttp://hdl.handle.net/10722/135020
ISSN
2015 Impact Factor: 2.487
2015 SCImago Journal Rankings: 1.416
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorBao, Sen_HK
dc.contributor.authorJiang, Ren_HK
dc.contributor.authorKwan, Wen_HK
dc.contributor.authorWang, Ben_HK
dc.contributor.authorMa, Xen_HK
dc.contributor.authorSong, YQen_HK
dc.date.accessioned2011-07-27T01:26:03Z-
dc.date.available2011-07-27T01:26:03Z-
dc.date.issued2011en_HK
dc.identifier.citationJournal of Human Genetics, 2011, v. 56 n. 6, p. 406-414en_HK
dc.identifier.issn1434-5161en_HK
dc.identifier.urihttp://hdl.handle.net/10722/135020-
dc.description.abstractNext-generation high-throughput DNA sequencing technologies have advanced progressively in sequence-based genomic research and novel biological applications with the promise of sequencing DNA at unprecedented speed. These new non-Sanger-based technologies feature several advantages when compared with traditional sequencing methods in terms of higher sequencing speed, lower per run cost and higher accuracy. However, reads from next-generation sequencing (NGS) platforms, such as 454/Roche, ABI/SOLiD and Illumina/Solexa, are usually short, thereby restricting the applications of NGS platforms in genome assembly and annotation. We presented an overview of the challenges that these novel technologies meet and particularly illustrated various bioinformatics attempts on mapping and assembly for problem solving. We then compared the performance of several programs in these two fields, and further provided advices on selecting suitable tools for specific biological applications.en_HK
dc.languageengen_US
dc.publisherSpringer Japan. The Journal's web site is located at http://link.springer.de/link/service/journals/10038/index.htmen_HK
dc.relation.ispartofJournal of Human Geneticsen_HK
dc.rightsThe original publication is available at www.springerlink.com-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subject.meshChromosome Mappingen_HK
dc.subject.meshComputational Biology - methodsen_HK
dc.subject.meshHigh-Throughput Nucleotide Sequencingen_HK
dc.subject.meshMolecular Sequence Annotationen_HK
dc.subject.meshSoftware - standardsen_HK
dc.titleEvaluation of next-generation sequencing software in mapping and assemblyen_HK
dc.typeArticleen_HK
dc.identifier.emailKwan, W: hcxckwk@hku.hken_HK
dc.identifier.emailSong, YQ: songy@hku.hk-
dc.identifier.authoritySong, YQ=rp00488en_HK
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1038/jhg.2011.43en_HK
dc.identifier.pmid21525877-
dc.identifier.scopuseid_2-s2.0-79959640102en_HK
dc.identifier.hkuros188467en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-79959640102&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume56en_HK
dc.identifier.issue6en_HK
dc.identifier.spage406en_HK
dc.identifier.epage414en_HK
dc.identifier.isiWOS:000292028000002-
dc.publisher.placeJapanen_HK
dc.identifier.scopusauthoridSong, YQ=7404921212en_HK
dc.identifier.scopusauthoridMa, X=35196580300en_HK
dc.identifier.scopusauthoridWang, B=23104530700en_HK
dc.identifier.scopusauthoridKwan, W=36878843300en_HK
dc.identifier.scopusauthoridJiang, R=26422313900en_HK
dc.identifier.scopusauthoridBao, S=53663218300en_HK
dc.identifier.citeulike9229221-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats