File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Validation of swept-source optical coherence tomography (SS-OCT) for the diagnosis of occlusal caries

TitleValidation of swept-source optical coherence tomography (SS-OCT) for the diagnosis of occlusal caries
Authors
KeywordsCross-sectional imaging
Diagnosis
Occlusal caries
ROC analysis
Sensitivity
Specificity
SS-OCT
Issue Date2010
PublisherElsevier Ltd. The Journal's web site is located at http://www.elsevier.com/locate/jdent
Citation
Journal Of Dentistry, 2010, v. 38 n. 8, p. 655-665 How to Cite?
AbstractObjectives: In this laboratory study, we examined the use of a swept-source optical coherence tomography (SS-OCT) as a diagnostic tool for occlusal caries. Methods: One-hundred and eleven investigation sites of occlusal fissures were selected from 62 extracted teeth and examined visually using conventional dental equipment without any magnification. SS-OCT observations were carried out on the same locations as where the conventional examination had been performed. The teeth were then sectioned using a diamond saw and directly viewed under a confocal laser scanning microscope (CLSM). Presence and extent of caries was scored in each observation and the obtained results from SS-OCT and conventional visual inspection were compared with the CLSM. The reproducibility and indices of sensitivity and specificity of SS-OCT were calculated and compared with those of the visual inspection. The results were statistically analyzed using receiver operating characteristic (ROC) curve and Spearman rank correlation test. Results: SS-OCT could clearly detect the presence of enamel demineralization lesion in a tomography image synthesized based on the backscatter signal (sensitivity = 0.98). Although the sensitivity for dentine caries of SS-OCT was over that of the visual inspection, the detection level was decreased to 0.60. When the methods were compared to the CLSM, the diagnostic accuracy of SS-OCT was better than that of the conventional visual inspection (Az values of visual inspection and SS-OCT, 0.74 versus 0.86 for enamel demineralization, 0.68 versus 0.80 for dentine caries; Spearman's correlation coefficients to CLSM; visual inspection: 0.665, SS-OCT: 0.824). Conclusions: The carious demineralization, especially in enamel, can be clearly discriminated as a highlighted area due to scattering of light matches the location of demineralized area at the base of the fissure and the results correlated well with the CLSM. © 2010 Elsevier Ltd. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/134972
ISSN
2015 Impact Factor: 3.109
2015 SCImago Journal Rankings: 1.029
ISI Accession Number ID
Funding AgencyGrant Number
Japan Society for the Promotion of Science21592415
Ministry of Health, Labor and Welfare21A-8
Japanese Ministry of Education
Funding Information:

This work was in part supported by the Grant-in-Aid for Scientific Research (No. 21592415) from the Japan Society for the Promotion of Science, in part by the Research Grant for Longevity Sciences (21A-8) from Ministry of Health, Labor and Welfare, and in part from the Japanese Ministry of Education, Global Center of Excellence (GCOE) Program, International Research Center for Molecular Science in Tooth and Bone Diseases.

References

 

DC FieldValueLanguage
dc.contributor.authorShimada, Yen_HK
dc.contributor.authorSadr, Aen_HK
dc.contributor.authorBurrow, MFen_HK
dc.contributor.authorTagami, Jen_HK
dc.contributor.authorOzawa, Nen_HK
dc.contributor.authorSumi, Yen_HK
dc.date.accessioned2011-07-27T01:25:14Z-
dc.date.available2011-07-27T01:25:14Z-
dc.date.issued2010en_HK
dc.identifier.citationJournal Of Dentistry, 2010, v. 38 n. 8, p. 655-665en_HK
dc.identifier.issn0300-5712en_HK
dc.identifier.urihttp://hdl.handle.net/10722/134972-
dc.description.abstractObjectives: In this laboratory study, we examined the use of a swept-source optical coherence tomography (SS-OCT) as a diagnostic tool for occlusal caries. Methods: One-hundred and eleven investigation sites of occlusal fissures were selected from 62 extracted teeth and examined visually using conventional dental equipment without any magnification. SS-OCT observations were carried out on the same locations as where the conventional examination had been performed. The teeth were then sectioned using a diamond saw and directly viewed under a confocal laser scanning microscope (CLSM). Presence and extent of caries was scored in each observation and the obtained results from SS-OCT and conventional visual inspection were compared with the CLSM. The reproducibility and indices of sensitivity and specificity of SS-OCT were calculated and compared with those of the visual inspection. The results were statistically analyzed using receiver operating characteristic (ROC) curve and Spearman rank correlation test. Results: SS-OCT could clearly detect the presence of enamel demineralization lesion in a tomography image synthesized based on the backscatter signal (sensitivity = 0.98). Although the sensitivity for dentine caries of SS-OCT was over that of the visual inspection, the detection level was decreased to 0.60. When the methods were compared to the CLSM, the diagnostic accuracy of SS-OCT was better than that of the conventional visual inspection (Az values of visual inspection and SS-OCT, 0.74 versus 0.86 for enamel demineralization, 0.68 versus 0.80 for dentine caries; Spearman's correlation coefficients to CLSM; visual inspection: 0.665, SS-OCT: 0.824). Conclusions: The carious demineralization, especially in enamel, can be clearly discriminated as a highlighted area due to scattering of light matches the location of demineralized area at the base of the fissure and the results correlated well with the CLSM. © 2010 Elsevier Ltd. All rights reserved.en_HK
dc.languageengen_US
dc.publisherElsevier Ltd. The Journal's web site is located at http://www.elsevier.com/locate/jdenten_HK
dc.relation.ispartofJournal of Dentistryen_HK
dc.subjectCross-sectional imagingen_HK
dc.subjectDiagnosisen_HK
dc.subjectOcclusal cariesen_HK
dc.subjectROC analysisen_HK
dc.subjectSensitivityen_HK
dc.subjectSpecificityen_HK
dc.subjectSS-OCTen_HK
dc.subject.meshDental Caries - diagnosis-
dc.subject.meshMicroscopy, Confocal-
dc.subject.meshObserver Variation-
dc.subject.meshReproducibility of Results-
dc.subject.meshTomography, Optical Coherence - methods-
dc.titleValidation of swept-source optical coherence tomography (SS-OCT) for the diagnosis of occlusal cariesen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0300-5712&volume=38&issue=8&spage=655&epage=665&date=2010&atitle=Validation+of+swept-source+optical+coherence+tomography+(SS-OCT)+for+the+diagnosis+of+occlusal+caries-
dc.identifier.emailBurrow, MF:mfburr58@hku.hken_HK
dc.identifier.authorityBurrow, MF=rp01306en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.jdent.2010.05.004en_HK
dc.identifier.pmid20470855-
dc.identifier.scopuseid_2-s2.0-77953688867en_HK
dc.identifier.hkuros186554en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-77953688867&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume38en_HK
dc.identifier.issue8en_HK
dc.identifier.spage655en_HK
dc.identifier.epage665en_HK
dc.identifier.isiWOS:000280121100008-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridShimada, Y=7402123770en_HK
dc.identifier.scopusauthoridSadr, A=35276097500en_HK
dc.identifier.scopusauthoridBurrow, MF=7005876730en_HK
dc.identifier.scopusauthoridTagami, J=7005967527en_HK
dc.identifier.scopusauthoridOzawa, N=34875537800en_HK
dc.identifier.scopusauthoridSumi, Y=7102246538en_HK
dc.identifier.citeulike7176650-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats