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Article: The incorporation of casein phosphopeptide-amorphous calcium phosphate into a glass ionomer cement

TitleThe incorporation of casein phosphopeptide-amorphous calcium phosphate into a glass ionomer cement
Authors
KeywordsCPP-ACP
Demineralization
Glass ionomer cement
Ion release
Mechanical properties
Issue Date2011
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/dental
Citation
Dental Materials, 2011, v. 27 n. 3, p. 235-243 How to Cite?
AbstractObjectives: The aim of this study was to measure the effect of incorporating CPP-ACP into an autocure GIC on physical and mechanical properties, ion release and enamel demineralization inhibition. Methods: Physical and mechanical properties were evaluated using tests specified by the International Organization for Standardization (ISO). Concentrations of fluoride, calcium and inorganic phosphate in deionized water (pH 6.9) and lactic acid (pH 4.8) were measured up to five months. Cavities on human extracted molars were prepared, restored with GIC (control), CPP-ACP modified GIC or resin composite, then stored in 50 mM lactic acid solution at pH 4.8 for 4 days. Sections of demineralized enamel were examined using polarized light microscopy followed by lesion area measurement. Results: The incorporation of up to 5% CPP-ACP into Fuji VII decreased the cements' strength and prolonged setting time. However, values remained within ISO limits. The incorporation of 3 or 5% CPP-ACP significantly decreased fluoride release, while higher calcium and inorganic phosphate release occurred. The demineralized enamel area adjacent to GIC with 3 or 5% CPP-ACP was significantly smaller compared to GIC control. Significance: The incorporation of 3% CPP-ACP into GIC has the potential to improve its anticariogenic ability without adversely affecting its mechanical properties. © 2010 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/134966
ISSN
2015 Impact Factor: 3.931
2015 SCImago Journal Rankings: 1.339
ISI Accession Number ID
Funding AgencyGrant Number
Jordan University of Science and Technology, Irbid, Jordan
School of Dental Science, University of Melbourne
Australian Dental Research Foundation, CRC Oral Health
Funding Information:

Dr. Hanan Al Zraikat was a student receiving financial support from Jordan University of Science and Technology, Irbid, Jordan. All other authors were employed by the University of Melbourne and did not receive consultant fees for this work. Financial support for this work was provided by The School of Dental Science, The University of Melbourne and The Australian Dental Research Foundation, CRC Oral Health. Thanks to GC Corporation, Tokyo, Japan, for supplying the glass ionomer cement materials. The assistance of Mr. Ilya Zalizniak is gratefully acknowledged.

References

 

DC FieldValueLanguage
dc.contributor.authorAl Zraikat, Hen_HK
dc.contributor.authorPalamara, JEAen_HK
dc.contributor.authorMesser, HHen_HK
dc.contributor.authorBurrow, MFen_HK
dc.contributor.authorReynolds, ECen_HK
dc.date.accessioned2011-07-27T01:25:10Z-
dc.date.available2011-07-27T01:25:10Z-
dc.date.issued2011en_HK
dc.identifier.citationDental Materials, 2011, v. 27 n. 3, p. 235-243en_HK
dc.identifier.issn0109-5641en_HK
dc.identifier.urihttp://hdl.handle.net/10722/134966-
dc.description.abstractObjectives: The aim of this study was to measure the effect of incorporating CPP-ACP into an autocure GIC on physical and mechanical properties, ion release and enamel demineralization inhibition. Methods: Physical and mechanical properties were evaluated using tests specified by the International Organization for Standardization (ISO). Concentrations of fluoride, calcium and inorganic phosphate in deionized water (pH 6.9) and lactic acid (pH 4.8) were measured up to five months. Cavities on human extracted molars were prepared, restored with GIC (control), CPP-ACP modified GIC or resin composite, then stored in 50 mM lactic acid solution at pH 4.8 for 4 days. Sections of demineralized enamel were examined using polarized light microscopy followed by lesion area measurement. Results: The incorporation of up to 5% CPP-ACP into Fuji VII decreased the cements' strength and prolonged setting time. However, values remained within ISO limits. The incorporation of 3 or 5% CPP-ACP significantly decreased fluoride release, while higher calcium and inorganic phosphate release occurred. The demineralized enamel area adjacent to GIC with 3 or 5% CPP-ACP was significantly smaller compared to GIC control. Significance: The incorporation of 3% CPP-ACP into GIC has the potential to improve its anticariogenic ability without adversely affecting its mechanical properties. © 2010 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.en_HK
dc.languageengen_US
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/dentalen_HK
dc.relation.ispartofDental Materialsen_HK
dc.subjectCPP-ACPen_HK
dc.subjectDemineralizationen_HK
dc.subjectGlass ionomer cementen_HK
dc.subjectIon releaseen_HK
dc.subjectMechanical propertiesen_HK
dc.subject.meshCariostatic Agents - chemistry-
dc.subject.meshCaseins - chemistry-
dc.subject.meshDental Restoration, Permanent - methods-
dc.subject.meshGlass Ionomer Cements - chemistry-
dc.subject.meshTooth Demineralization - prevention and control-
dc.titleThe incorporation of casein phosphopeptide-amorphous calcium phosphate into a glass ionomer cementen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0109-5641&volume=27&issue=3&spage=235&epage=243&date=2011&atitle=The+incorporation+of+casein+phosphopeptide-amorphous+calcium+phosphate+into+a+glass+ionmer+cement-
dc.identifier.emailBurrow, MF:mfburr58@hku.hken_HK
dc.identifier.authorityBurrow, MF=rp01306en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.dental.2010.10.008en_HK
dc.identifier.pmid21087789-
dc.identifier.scopuseid_2-s2.0-79651473853en_HK
dc.identifier.hkuros186546en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-79651473853&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume27en_HK
dc.identifier.issue3en_HK
dc.identifier.spage235en_HK
dc.identifier.epage243en_HK
dc.identifier.isiWOS:000286973400006-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridAl Zraikat, H=36622619300en_HK
dc.identifier.scopusauthoridPalamara, JEA=36622764100en_HK
dc.identifier.scopusauthoridMesser, HH=7102353781en_HK
dc.identifier.scopusauthoridBurrow, MF=7005876730en_HK
dc.identifier.scopusauthoridReynolds, EC=35550178300en_HK
dc.identifier.citeulike8298447-

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