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Article: The clinical application of surface pH measurements to longitudinally assess white spot enamel lesions.

TitleThe clinical application of surface pH measurements to longitudinally assess white spot enamel lesions.
Authors
Issue Date2010
PublisherElsevier Ltd. The Journal's web site is located at http://www.elsevier.com/locate/jdent
Citation
Journal Of Dentistry, 2010, v. 38 n. 7, p. 584-590 How to Cite?
AbstractOBJECTIVES: Means of objectively assessing white spot enamel lesions (WSEL) are critical for determining their potential activity and monitoring the success of preventive treatments. The aim of this study was to determine whether surface pH measurements of WSEL changed during a preventive course of care designed to remineralize the lesions. METHODS: Eight healthy subjects (1 male and 7 females) with at least one WSEL were recruited (19-64 years). Each subject was placed on a preventive treatment program including the daily application of a CPP-ACP paste (MI paste, GC Corp., Japan) with custom fitted trays for more than 6 months. The surface pH values of sound enamel and WSEL were monitored for up to 2 years using a micro-pH sensor. The visual appearance of the WSEL was monitored via digital photography, and images were analyzed qualitatively on a 5-point scale to assess the success of the remineralization preventive program. The relationship between the qualitative assessment of WSEL appearance and the WSEL pH was investigated using a Spearman's rho non-parametric correlation. RESULTS: The surface pH of the WSEL was different to that of the sound enamel surrounding it in all patients at all times. All lesions showed visual improvement as the treatment period progressed. The pH of the WSEL increased towards that of sound enamel over the course of treatment significantly correlating with the visual improvement of the lesion (rho=0.63, p<0.0001). CONCLUSIONS: The clinical assessment of WSEL surface pH changes with time may have utility as an additional objective measure for the assessment of WSEL activity. Copyright 2010 Elsevier Ltd. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/134964
ISSN
ISI Accession Number ID
Funding AgencyGrant Number
Japan Society for the Promotion of Science21592413
Global Center of Excellence Program for International Research Center for Molecular Science in Tooth and Bone Diseases at Tokyo Medical and Dental University
Funding Information:

This project was supported by Grant #21592413 from the Japan Society for the Promotion of Science, and for Global Center of Excellence Program for International Research Center for Molecular Science in Tooth and Bone Diseases at Tokyo Medical and Dental University. Dr. Glenn Walker and Mr. Masaomi Ikeda are acknowledged for assistance with statistical analysis.

 

DC FieldValueLanguage
dc.contributor.authorKitasako, Yen_HK
dc.contributor.authorCochrane, NJen_HK
dc.contributor.authorKhairul, Men_HK
dc.contributor.authorShida, Ken_HK
dc.contributor.authorAdams, GGen_HK
dc.contributor.authorBurrow, MFen_HK
dc.contributor.authorReynolds, ECen_HK
dc.contributor.authorTagami, Jen_HK
dc.date.accessioned2011-07-27T01:25:10Z-
dc.date.available2011-07-27T01:25:10Z-
dc.date.issued2010en_HK
dc.identifier.citationJournal Of Dentistry, 2010, v. 38 n. 7, p. 584-590en_HK
dc.identifier.issn1879-176Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/134964-
dc.description.abstractOBJECTIVES: Means of objectively assessing white spot enamel lesions (WSEL) are critical for determining their potential activity and monitoring the success of preventive treatments. The aim of this study was to determine whether surface pH measurements of WSEL changed during a preventive course of care designed to remineralize the lesions. METHODS: Eight healthy subjects (1 male and 7 females) with at least one WSEL were recruited (19-64 years). Each subject was placed on a preventive treatment program including the daily application of a CPP-ACP paste (MI paste, GC Corp., Japan) with custom fitted trays for more than 6 months. The surface pH values of sound enamel and WSEL were monitored for up to 2 years using a micro-pH sensor. The visual appearance of the WSEL was monitored via digital photography, and images were analyzed qualitatively on a 5-point scale to assess the success of the remineralization preventive program. The relationship between the qualitative assessment of WSEL appearance and the WSEL pH was investigated using a Spearman's rho non-parametric correlation. RESULTS: The surface pH of the WSEL was different to that of the sound enamel surrounding it in all patients at all times. All lesions showed visual improvement as the treatment period progressed. The pH of the WSEL increased towards that of sound enamel over the course of treatment significantly correlating with the visual improvement of the lesion (rho=0.63, p<0.0001). CONCLUSIONS: The clinical assessment of WSEL surface pH changes with time may have utility as an additional objective measure for the assessment of WSEL activity. Copyright 2010 Elsevier Ltd. All rights reserved.en_HK
dc.languageengen_US
dc.publisherElsevier Ltd. The Journal's web site is located at http://www.elsevier.com/locate/jdent-
dc.relation.ispartofJournal of Dentistryen_HK
dc.subject.meshAdministration, Topical-
dc.subject.meshCariostatic Agents - administration and dosage - therapeutic use-
dc.subject.meshCaseins - administration and dosage - therapeutic use-
dc.subject.meshDental Caries - pathology - physiopathology - prevention and control-
dc.subject.meshTooth Remineralization - methods-
dc.titleThe clinical application of surface pH measurements to longitudinally assess white spot enamel lesions.en_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0300-5712&volume=38&issue=7&spage=584&epage=590&date=2010&atitle=The+clinical+application+of+surface+pH+measurements+to+longitudinally+assess+white+spot+enamel+lesions-
dc.identifier.emailBurrow, MF:mfburr58@hku.hken_HK
dc.identifier.authorityBurrow, MF=rp01306en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.jdent.2010.04.010en_HK
dc.identifier.pmid20433891-
dc.identifier.scopuseid_2-s2.0-77957254014en_HK
dc.identifier.hkuros186542en_US
dc.identifier.volume38en_HK
dc.identifier.issue7en_HK
dc.identifier.spage584en_HK
dc.identifier.epage590en_HK
dc.identifier.isiWOS:000279361700010-
dc.identifier.scopusauthoridKitasako, Y=7003435929en_HK
dc.identifier.scopusauthoridCochrane, NJ=14830194400en_HK
dc.identifier.scopusauthoridKhairul, M=36053255300en_HK
dc.identifier.scopusauthoridShida, K=26326505400en_HK
dc.identifier.scopusauthoridAdams, GG=7401506932en_HK
dc.identifier.scopusauthoridBurrow, MF=7005876730en_HK
dc.identifier.scopusauthoridReynolds, EC=35550178300en_HK
dc.identifier.scopusauthoridTagami, J=7005967527en_HK
dc.identifier.citeulike7109460-

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