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Article: An expeditious asymmetric synthesis of the pentacyclic core of the cortistatins by an intramolecular (4+3) cycloaddition

TitleAn expeditious asymmetric synthesis of the pentacyclic core of the cortistatins by an intramolecular (4+3) cycloaddition
Authors
Liu, LLChiu, P
Issue Date2011
PublisherRoyal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/Publishing/Journals/cc/index.asp
Citation
Chemical Communications, 2011, v. 47 n. 12, p. 3416-3417 How to Cite?
DOI: http://dx.doi.org/10.1039/c1cc00087j
AbstractA concise, asymmetric synthesis of the pentacyclic framework of the cortistatins has been accomplished in 12 steps from commercially available starting materials, employing a highly diastereoselective intramolecular (4+3) cycloaddition of epoxy enolsilanes as the key step. © 2011 The Royal Society of Chemistry.
Persistent Identifierhttp://hdl.handle.net/10722/134775
ISSN
1359-7345
2023 Impact Factor: 4.3
2023 SCImago Journal Rankings: 1.133
ISI Accession Number ID
WOS:000288085600019
Funding AgencyGrant Number
University of Hong Kong
Research Grants Council of Hong Kong SARHKU 7011/08P
Funding Information:

We thank the University of Hong Kong Strategic Research Theme on Drugs, and the Research Grants Council of Hong Kong SAR (GRF Project No. HKU 7011/08P) for funding.

References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorLiu, LLen_HK
dc.contributor.authorChiu, Pen_HK
dc.date.accessioned2011-07-18T05:01:12Z-
dc.date.available2011-07-18T05:01:12Z-
dc.date.issued2011en_HK
dc.identifier.citationChemical Communications, 2011, v. 47 n. 12, p. 3416-3417en_HK
dc.identifier.issn1359-7345en_HK
dc.identifier.urihttp://hdl.handle.net/10722/134775-
dc.description.abstractA concise, asymmetric synthesis of the pentacyclic framework of the cortistatins has been accomplished in 12 steps from commercially available starting materials, employing a highly diastereoselective intramolecular (4+3) cycloaddition of epoxy enolsilanes as the key step. © 2011 The Royal Society of Chemistry.en_HK
dc.languageeng-
dc.publisherRoyal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/Publishing/Journals/cc/index.aspen_HK
dc.relation.ispartofChemical Communicationsen_HK
dc.subject.meshHeterocyclic Compounds with 4 or More Rings - chemical synthesis - chemistry-
dc.subject.meshIsoquinolines - chemical synthesis - chemistry-
dc.subject.meshPolycyclic Compounds - chemical synthesis - chemistry-
dc.subject.meshStereoisomerism-
dc.subject.meshSubstrate Specificity-
dc.titleAn expeditious asymmetric synthesis of the pentacyclic core of the cortistatins by an intramolecular (4+3) cycloadditionen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1359-7345&volume=47&issue=12&spage=3416&epage=3417&date=2011&atitle=An+expeditious+asymmetric+synthesis+of+the+pentacyclic+core+of+the+cortistatins+by+an+intramolecular+(4+3)+cycloaddition-
dc.identifier.emailChiu, P:pchiu@hku.hken_HK
dc.identifier.authorityChiu, P=rp00680en_HK
dc.description.naturepostprint-
dc.identifier.doi10.1039/c1cc00087jen_HK
dc.identifier.pmid21311803-
dc.identifier.scopuseid_2-s2.0-79952418001en_HK
dc.identifier.hkuros186263-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-79952418001&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume47en_HK
dc.identifier.issue12en_HK
dc.identifier.spage3416en_HK
dc.identifier.epage3417en_HK
dc.identifier.eissn1364-548X-
dc.identifier.isiWOS:000288085600019-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridLiu, LL=35215540300en_HK
dc.identifier.scopusauthoridChiu, P=11140148700en_HK
dc.identifier.issnl1359-7345-

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