Article: Short or long sleep duration is associated with memory impairment in older chinese: The Guangzhou Biobank Cohort Study
| Title | Short or long sleep duration is associated with memory impairment in older chinese: The Guangzhou Biobank Cohort Study |
|---|---|
| Authors | Xu, L1 Jiang, CQ3 Lam, TH1 Liu, B3 Jin, YL3 Zhu, T3 Zhang, WS3 Cheng, KK2 Thomas, GN2 |
| Keywords | Insomnia Memory impairment Napping Sleep Sleep duration |
| Issue Date | 2011 |
| Publisher | The American Academy of Sleep Medicine. The Journal's web site is located at http://www.journalsleep.org |
| Citation | Sleep, 2011, v. 34 n. 5, p. 575-580 [How to Cite?] |
| Abstract | Study Objectives: To examine the association between sleep-related factors and memory impairment. Design: Cross-sectional study Setting: Community-based study in Guangzhou, China. Participants: 28,670 older Chinese (20,776 women and 7,894 men) aged 50 to 85 years. Measurements and Results: Demographic and socioeconomic data, sleep-related factors, and cognitive function were collected by face-to-face interview. Potential confounders, such as employment and occupational status, smoking, alcohol and tea use, physical activity, self-rated health, anthropometry, blood pressure, and fasting plasma glucose and lipids were measured. After adjusting for multiple potential confounders, an inverted U-shaped association between sleep duration and delayed word recall test (DWRT) score, a validated measure of memory impairment, was found, with 7 to 8 h of habitual sleep duration showing the highest score (P-values for trend from 3 to 7 h and from 7 to ≥ 10 h were all ≤ 0.001). Compared to sleep duration of 7 h, the adjusted odds ratio for memory impairment from the sleep duration of 3 to 4 or ≥ 10 h was 1.29 (95% confidence interval 1.07-1.56) and 1.52 (1.25-1.86), respectively. Subjects with daily napping, morning tiredness, or insomnia had significantly lower DWRT scores than those without (P ranged from < 0.001 to 0.01).Conclusions: Short or long sleep duration was an important sleep-related factor independently associated with memory impairment and may be a useful marker for increased risk of cognitive impairment in older people. © Copyright 2011 Associated Professional Sleep Societies, LLC. |
| ISSN | 0161-8105 2011 Impact Factor: 5.051 2011 SCImago Journal Rankings: 0.343 |
| PubMed Central ID | PMC3079936 |
| References | References in Scopus |
| dc.contributor.author | Xu, L |
|---|---|
| dc.contributor.author | Jiang, CQ |
| dc.contributor.author | Lam, TH |
| dc.contributor.author | Liu, B |
| dc.contributor.author | Jin, YL |
| dc.contributor.author | Zhu, T |
| dc.contributor.author | Zhang, WS |
| dc.contributor.author | Cheng, KK |
| dc.contributor.author | Thomas, GN |
| dc.date.accessioned | 2011-06-17T09:22:12Z |
| dc.date.available | 2011-06-17T09:22:12Z |
| dc.date.issued | 2011 |
| dc.description.abstract | Study Objectives: To examine the association between sleep-related factors and memory impairment. Design: Cross-sectional study Setting: Community-based study in Guangzhou, China. Participants: 28,670 older Chinese (20,776 women and 7,894 men) aged 50 to 85 years. Measurements and Results: Demographic and socioeconomic data, sleep-related factors, and cognitive function were collected by face-to-face interview. Potential confounders, such as employment and occupational status, smoking, alcohol and tea use, physical activity, self-rated health, anthropometry, blood pressure, and fasting plasma glucose and lipids were measured. After adjusting for multiple potential confounders, an inverted U-shaped association between sleep duration and delayed word recall test (DWRT) score, a validated measure of memory impairment, was found, with 7 to 8 h of habitual sleep duration showing the highest score (P-values for trend from 3 to 7 h and from 7 to ≥ 10 h were all ≤ 0.001). Compared to sleep duration of 7 h, the adjusted odds ratio for memory impairment from the sleep duration of 3 to 4 or ≥ 10 h was 1.29 (95% confidence interval 1.07-1.56) and 1.52 (1.25-1.86), respectively. Subjects with daily napping, morning tiredness, or insomnia had significantly lower DWRT scores than those without (P ranged from < 0.001 to 0.01).Conclusions: Short or long sleep duration was an important sleep-related factor independently associated with memory impairment and may be a useful marker for increased risk of cognitive impairment in older people. © Copyright 2011 Associated Professional Sleep Societies, LLC. |
| dc.description.nature | link_to_OA_fulltext |
| dc.identifier.citation | Sleep, 2011, v. 34 n. 5, p. 575-580 [How to Cite?] |
| dc.identifier.epage | 580 |
| dc.identifier.hkuros | 185482 |
| dc.identifier.isi | WOS:000291145800007 |
| dc.identifier.issn | 0161-8105 2011 Impact Factor: 5.051 2011 SCImago Journal Rankings: 0.343 |
| dc.identifier.issue | 5 |
| dc.identifier.openurl | ![]() |
| dc.identifier.pmcid | PMC3079936 |
| dc.identifier.pmid | 21532950 |
| dc.identifier.scopus | eid_2-s2.0-79955555744 |
| dc.identifier.spage | 575 |
| dc.identifier.uri | http://hdl.handle.net/10722/134493 |
| dc.identifier.volume | 34 |
| dc.language | eng |
| dc.publisher | The American Academy of Sleep Medicine. The Journal's web site is located at http://www.journalsleep.org |
| dc.publisher.place | United States |
| dc.relation.ispartof | Sleep |
| dc.relation.references | References in Scopus |
| dc.subject | Insomnia |
| dc.subject | Memory impairment |
| dc.subject | Napping |
| dc.subject | Sleep |
| dc.subject | Sleep duration |
| dc.title | Short or long sleep duration is associated with memory impairment in older chinese: The Guangzhou Biobank Cohort Study |
| dc.type | Article |
Author Affiliations
- The University of Hong Kong
- University of Birmingham
- Guangzhou No. 12 Hospital


