Article: Osmium(vi) complexes as a new class of potential anti-cancer agents
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- Publisher Website: 10.1039/c0cc04515b
- Scopus: eid_2-s2.0-79551475837
- PMID: 21203649
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| Title | Osmium(vi) complexes as a new class of potential anti-cancer agents | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Authors | Ni, WX2 Man, WL2 Cheung, MTW2 Sun, RWY1 Shu, YL3 Lam, YW2 Che, CM1 Lau, TC2 | ||||||||
| Issue Date | 2011 | ||||||||
| Publisher | Royal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/Publishing/Journals/cc/index.asp | ||||||||
| Citation | Chemical Communications, 2011, v. 47 n. 7, p. 2140-2142 [How to Cite?] DOI: http://dx.doi.org/10.1039/c0cc04515b | ||||||||
| Abstract | A nitridoosmium(vi) complex [Os VI(N)(sap)(OH 2)Cl] (H 2sap = N-salicylidene-2-aminophenol) displays prominent in vitro and in vivo anti-cancer properties, induces S- and G2/M-phase arrest and forms a stable adduct with dianionic 5′-guanosine monophosphate. © 2011 The Royal Society of Chemistry. | ||||||||
| ISSN | 1359-7345 2011 Impact Factor: 6.169 2011 SCImago Journal Rankings: 0.507 | ||||||||
| DOI | http://dx.doi.org/10.1039/c0cc04515b | ||||||||
| ISI Accession Number ID | WOS:000286766600059
Funding Information: We acknowledge the Research Grants Council of Hong Kong (CityU 101607), the Area of Excellence Scheme (AoE/P-10/01) administered by the University Grants Committee (HKSAR, China), and the ITF-Tier 2 project (ITS/134/09FP) administrated by the Innovation and Technology Commission (HKSAR, China). | ||||||||
| References | References in Scopus | ||||||||
| Grants | Discovery and Pre-Clinical Evaluation of Promising Metal-Based Anti-Cancer Drug Leads Institute of molecular technology for drug discovery and synthesis |
| dc.contributor.author | Ni, WX | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| dc.contributor.author | Man, WL | ||||||||
| dc.contributor.author | Cheung, MTW | ||||||||
| dc.contributor.author | Sun, RWY | ||||||||
| dc.contributor.author | Shu, YL | ||||||||
| dc.contributor.author | Lam, YW | ||||||||
| dc.contributor.author | Che, CM | ||||||||
| dc.contributor.author | Lau, TC | ||||||||
| dc.date.accessioned | 2011-06-17T09:18:42Z | ||||||||
| dc.date.available | 2011-06-17T09:18:42Z | ||||||||
| dc.date.issued | 2011 | ||||||||
| dc.description.abstract | A nitridoosmium(vi) complex [Os VI(N)(sap)(OH 2)Cl] (H 2sap = N-salicylidene-2-aminophenol) displays prominent in vitro and in vivo anti-cancer properties, induces S- and G2/M-phase arrest and forms a stable adduct with dianionic 5′-guanosine monophosphate. © 2011 The Royal Society of Chemistry. | ||||||||
| dc.description.grant | Discovery and Pre-Clinical Evaluation of Promising Metal-Based Anti-Cancer Drug Leads | ||||||||
| dc.description.grant | Institute of molecular technology for drug discovery and synthesis | ||||||||
| dc.description.grantcode | 102630 | ||||||||
| dc.description.grantcode | 8708 | ||||||||
| dc.description.nature | Link_to_subscribed_fulltext | ||||||||
| dc.identifier.citation | Chemical Communications, 2011, v. 47 n. 7, p. 2140-2142 [How to Cite?] DOI: http://dx.doi.org/10.1039/c0cc04515b | ||||||||
| dc.identifier.doi | http://dx.doi.org/10.1039/c0cc04515b | ||||||||
| dc.identifier.epage | 2142 | ||||||||
| dc.identifier.hkuros | 185777 | ||||||||
| dc.identifier.isi | WOS:000286766600059
Funding Information: We acknowledge the Research Grants Council of Hong Kong (CityU 101607), the Area of Excellence Scheme (AoE/P-10/01) administered by the University Grants Committee (HKSAR, China), and the ITF-Tier 2 project (ITS/134/09FP) administrated by the Innovation and Technology Commission (HKSAR, China). | ||||||||
| dc.identifier.issn | 1359-7345 2011 Impact Factor: 6.169 2011 SCImago Journal Rankings: 0.507 | ||||||||
| dc.identifier.issue | 7 | ||||||||
| dc.identifier.openurl | | ||||||||
| dc.identifier.pmid | 21203649 | ||||||||
| dc.identifier.scopus | eid_2-s2.0-79551475837 | ||||||||
| dc.identifier.spage | 2140 | ||||||||
| dc.identifier.uri | http://hdl.handle.net/10722/134368 | ||||||||
| dc.identifier.volume | 47 | ||||||||
| dc.language | eng | ||||||||
| dc.publisher | Royal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/Publishing/Journals/cc/index.asp | ||||||||
| dc.publisher.place | United Kingdom | ||||||||
| dc.relation.ispartof | Chemical Communications | ||||||||
| dc.relation.references | References in Scopus | ||||||||
| dc.subject.mesh | Antineoplastic Agents - chemistry - pharmacology | ||||||||
| dc.subject.mesh | Cell Cycle - drug effects | ||||||||
| dc.subject.mesh | Cell Line, Tumor | ||||||||
| dc.subject.mesh | Drug Screening Assays, Antitumor | ||||||||
| dc.subject.mesh | Osmium Compounds - chemistry - pharmacology | ||||||||
| dc.title | Osmium(vi) complexes as a new class of potential anti-cancer agents | ||||||||
| dc.type | Article |
Author Affiliations
- The University of Hong Kong
- City University of Hong Kong
- State Key Laboratory