File Download
 
Links for fulltext
(May Require Subscription)
 
Supplementary

Article: Osmium(vi) complexes as a new class of potential anti-cancer agents
  • Basic View
  • Metadata View
  • XML View
TitleOsmium(vi) complexes as a new class of potential anti-cancer agents
 
AuthorsNi, WX2
Man, WL2
Cheung, MTW2
Sun, RWY1
Shu, YL3
Lam, YW2
Che, CM1
Lau, TC2
 
Issue Date2011
 
PublisherRoyal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/Publishing/Journals/cc/index.asp
 
CitationChemical Communications, 2011, v. 47 n. 7, p. 2140-2142 [How to Cite?]
DOI: http://dx.doi.org/10.1039/c0cc04515b
 
AbstractA nitridoosmium(vi) complex [Os VI(N)(sap)(OH 2)Cl] (H 2sap = N-salicylidene-2-aminophenol) displays prominent in vitro and in vivo anti-cancer properties, induces S- and G2/M-phase arrest and forms a stable adduct with dianionic 5′-guanosine monophosphate. © 2011 The Royal Society of Chemistry.
 
ISSN1359-7345
2013 Impact Factor: 6.718
2013 SCImago Journal Rankings: 2.918
 
DOIhttp://dx.doi.org/10.1039/c0cc04515b
 
ISI Accession Number IDWOS:000286766600059
Funding AgencyGrant Number
Research Grants Council of Hong KongCityU 101607
Area of Excellence SchemeAoE/P-10/01
ITF-Tier 2ITS/134/09FP
Funding Information:

We acknowledge the Research Grants Council of Hong Kong (CityU 101607), the Area of Excellence Scheme (AoE/P-10/01) administered by the University Grants Committee (HKSAR, China), and the ITF-Tier 2 project (ITS/134/09FP) administrated by the Innovation and Technology Commission (HKSAR, China).

 
ReferencesReferences in Scopus
 
GrantsDiscovery and Pre-Clinical Evaluation of Promising Metal-Based Anti-Cancer Drug Leads
Institute of molecular technology for drug discovery and synthesis
 
DC FieldValue
dc.contributor.authorNi, WX
 
dc.contributor.authorMan, WL
 
dc.contributor.authorCheung, MTW
 
dc.contributor.authorSun, RWY
 
dc.contributor.authorShu, YL
 
dc.contributor.authorLam, YW
 
dc.contributor.authorChe, CM
 
dc.contributor.authorLau, TC
 
dc.date.accessioned2011-06-17T09:18:42Z
 
dc.date.available2011-06-17T09:18:42Z
 
dc.date.issued2011
 
dc.description.abstractA nitridoosmium(vi) complex [Os VI(N)(sap)(OH 2)Cl] (H 2sap = N-salicylidene-2-aminophenol) displays prominent in vitro and in vivo anti-cancer properties, induces S- and G2/M-phase arrest and forms a stable adduct with dianionic 5′-guanosine monophosphate. © 2011 The Royal Society of Chemistry.
 
dc.description.naturelink_to_subscribed_fulltext
 
dc.identifier.citationChemical Communications, 2011, v. 47 n. 7, p. 2140-2142 [How to Cite?]
DOI: http://dx.doi.org/10.1039/c0cc04515b
 
dc.identifier.doihttp://dx.doi.org/10.1039/c0cc04515b
 
dc.identifier.epage2142
 
dc.identifier.hkuros185777
 
dc.identifier.isiWOS:000286766600059
Funding AgencyGrant Number
Research Grants Council of Hong KongCityU 101607
Area of Excellence SchemeAoE/P-10/01
ITF-Tier 2ITS/134/09FP
Funding Information:

We acknowledge the Research Grants Council of Hong Kong (CityU 101607), the Area of Excellence Scheme (AoE/P-10/01) administered by the University Grants Committee (HKSAR, China), and the ITF-Tier 2 project (ITS/134/09FP) administrated by the Innovation and Technology Commission (HKSAR, China).

 
dc.identifier.issn1359-7345
2013 Impact Factor: 6.718
2013 SCImago Journal Rankings: 2.918
 
dc.identifier.issue7
 
dc.identifier.openurl
 
dc.identifier.pmid21203649
 
dc.identifier.scopuseid_2-s2.0-79551475837
 
dc.identifier.spage2140
 
dc.identifier.urihttp://hdl.handle.net/10722/134368
 
dc.identifier.volume47
 
dc.languageeng
 
dc.publisherRoyal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/Publishing/Journals/cc/index.asp
 
dc.publisher.placeUnited Kingdom
 
dc.relation.ispartofChemical Communications
 
dc.relation.projectDiscovery and Pre-Clinical Evaluation of Promising Metal-Based Anti-Cancer Drug Leads
 
dc.relation.projectInstitute of molecular technology for drug discovery and synthesis
 
dc.relation.referencesReferences in Scopus
 
dc.subject.meshAntineoplastic Agents - chemistry - pharmacology
 
dc.subject.meshCell Cycle - drug effects
 
dc.subject.meshCell Line, Tumor
 
dc.subject.meshDrug Screening Assays, Antitumor
 
dc.subject.meshOsmium Compounds - chemistry - pharmacology
 
dc.titleOsmium(vi) complexes as a new class of potential anti-cancer agents
 
dc.typeArticle
 
<?xml encoding="utf-8" version="1.0"?>
<item><contributor.author>Ni, WX</contributor.author>
<contributor.author>Man, WL</contributor.author>
<contributor.author>Cheung, MTW</contributor.author>
<contributor.author>Sun, RWY</contributor.author>
<contributor.author>Shu, YL</contributor.author>
<contributor.author>Lam, YW</contributor.author>
<contributor.author>Che, CM</contributor.author>
<contributor.author>Lau, TC</contributor.author>
<date.accessioned>2011-06-17T09:18:42Z</date.accessioned>
<date.available>2011-06-17T09:18:42Z</date.available>
<date.issued>2011</date.issued>
<identifier.citation>Chemical Communications, 2011, v. 47 n. 7, p. 2140-2142</identifier.citation>
<identifier.issn>1359-7345</identifier.issn>
<identifier.uri>http://hdl.handle.net/10722/134368</identifier.uri>
<description.abstract>A nitridoosmium(vi) complex [Os VI(N)(sap)(OH 2)Cl] (H 2sap = N-salicylidene-2-aminophenol) displays prominent in vitro and in vivo anti-cancer properties, induces S- and G2/M-phase arrest and forms a stable adduct with dianionic 5&#8242;-guanosine monophosphate. &#169; 2011 The Royal Society of Chemistry.</description.abstract>
<language>eng</language>
<publisher>Royal Society of Chemistry. The Journal&apos;s web site is located at http://www.rsc.org/Publishing/Journals/cc/index.asp</publisher>
<relation.ispartof>Chemical Communications</relation.ispartof>
<subject.mesh>Antineoplastic Agents - chemistry - pharmacology</subject.mesh>
<subject.mesh>Cell Cycle - drug effects</subject.mesh>
<subject.mesh>Cell Line, Tumor</subject.mesh>
<subject.mesh>Drug Screening Assays, Antitumor</subject.mesh>
<subject.mesh>Osmium Compounds - chemistry - pharmacology</subject.mesh>
<title>Osmium(vi) complexes as a new class of potential anti-cancer agents</title>
<type>Article</type>
<identifier.openurl>http://library.hku.hk:4550/resserv?sid=HKU:IR&amp;issn=1359-7345&amp;volume=47&amp;spage=2140&amp;epage=2142&amp;date=2011&amp;atitle=Osmium(VI)+complexes+as+a+new+class+of+potential+anti-cancer+agents</identifier.openurl>
<description.nature>link_to_subscribed_fulltext</description.nature>
<identifier.doi>10.1039/c0cc04515b</identifier.doi>
<identifier.pmid>21203649</identifier.pmid>
<identifier.scopus>eid_2-s2.0-79551475837</identifier.scopus>
<identifier.hkuros>185777</identifier.hkuros>
<relation.references>http://www.scopus.com/mlt/select.url?eid=2-s2.0-79551475837&amp;selection=ref&amp;src=s&amp;origin=recordpage</relation.references>
<identifier.volume>47</identifier.volume>
<identifier.issue>7</identifier.issue>
<identifier.spage>2140</identifier.spage>
<identifier.epage>2142</identifier.epage>
<identifier.isi>WOS:000286766600059</identifier.isi>
<publisher.place>United Kingdom</publisher.place>
<relation.project>Discovery and Pre-Clinical Evaluation of Promising Metal-Based Anti-Cancer Drug Leads</relation.project>
<relation.project>Institute of molecular technology for drug discovery and synthesis</relation.project>
</item>
Author Affiliations
  1. The University of Hong Kong
  2. City University of Hong Kong
  3. State Key Laboratory