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Article: Osmium(vi) complexes as a new class of potential anti-cancer agents

TitleOsmium(vi) complexes as a new class of potential anti-cancer agents
Authors
Issue Date2011
PublisherRoyal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/Publishing/Journals/cc/index.asp
Citation
Chemical Communications, 2011, v. 47 n. 7, p. 2140-2142 How to Cite?
AbstractA nitridoosmium(vi) complex [Os VI(N)(sap)(OH 2)Cl] (H 2sap = N-salicylidene-2-aminophenol) displays prominent in vitro and in vivo anti-cancer properties, induces S- and G2/M-phase arrest and forms a stable adduct with dianionic 5′-guanosine monophosphate. © 2011 The Royal Society of Chemistry.
Persistent Identifierhttp://hdl.handle.net/10722/134368
ISSN
2014 Impact Factor: 6.834
2014 SCImago Journal Rankings: 2.444
ISI Accession Number ID
Funding AgencyGrant Number
Research Grants Council of Hong KongCityU 101607
Area of Excellence SchemeAoE/P-10/01
ITF-Tier 2ITS/134/09FP
Funding Information:

We acknowledge the Research Grants Council of Hong Kong (CityU 101607), the Area of Excellence Scheme (AoE/P-10/01) administered by the University Grants Committee (HKSAR, China), and the ITF-Tier 2 project (ITS/134/09FP) administrated by the Innovation and Technology Commission (HKSAR, China).

References
Grants

 

DC FieldValueLanguage
dc.contributor.authorNi, WXen_HK
dc.contributor.authorMan, WLen_HK
dc.contributor.authorCheung, MTWen_HK
dc.contributor.authorSun, RWYen_HK
dc.contributor.authorShu, YLen_HK
dc.contributor.authorLam, YWen_HK
dc.contributor.authorChe, CMen_HK
dc.contributor.authorLau, TCen_HK
dc.date.accessioned2011-06-17T09:18:42Z-
dc.date.available2011-06-17T09:18:42Z-
dc.date.issued2011en_HK
dc.identifier.citationChemical Communications, 2011, v. 47 n. 7, p. 2140-2142en_HK
dc.identifier.issn1359-7345en_HK
dc.identifier.urihttp://hdl.handle.net/10722/134368-
dc.description.abstractA nitridoosmium(vi) complex [Os VI(N)(sap)(OH 2)Cl] (H 2sap = N-salicylidene-2-aminophenol) displays prominent in vitro and in vivo anti-cancer properties, induces S- and G2/M-phase arrest and forms a stable adduct with dianionic 5′-guanosine monophosphate. © 2011 The Royal Society of Chemistry.en_HK
dc.languageengen_US
dc.publisherRoyal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/Publishing/Journals/cc/index.aspen_HK
dc.relation.ispartofChemical Communicationsen_HK
dc.subject.meshAntineoplastic Agents - chemistry - pharmacology-
dc.subject.meshCell Cycle - drug effects-
dc.subject.meshCell Line, Tumor-
dc.subject.meshDrug Screening Assays, Antitumor-
dc.subject.meshOsmium Compounds - chemistry - pharmacology-
dc.titleOsmium(vi) complexes as a new class of potential anti-cancer agentsen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1359-7345&volume=47&spage=2140&epage=2142&date=2011&atitle=Osmium(VI)+complexes+as+a+new+class+of+potential+anti-cancer+agents-
dc.identifier.emailSun, RWY:rwysun@hku.hken_HK
dc.identifier.emailChe, CM:cmche@hku.hken_HK
dc.identifier.authoritySun, RWY=rp00781en_HK
dc.identifier.authorityChe, CM=rp00670en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1039/c0cc04515ben_HK
dc.identifier.pmid21203649en_HK
dc.identifier.scopuseid_2-s2.0-79551475837en_HK
dc.identifier.hkuros185777en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-79551475837&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume47en_HK
dc.identifier.issue7en_HK
dc.identifier.spage2140en_HK
dc.identifier.epage2142en_HK
dc.identifier.isiWOS:000286766600059-
dc.publisher.placeUnited Kingdomen_HK
dc.relation.projectDiscovery and Pre-Clinical Evaluation of Promising Metal-Based Anti-Cancer Drug Leads-
dc.relation.projectInstitute of molecular technology for drug discovery and synthesis-
dc.identifier.scopusauthoridNi, WX=38461465600en_HK
dc.identifier.scopusauthoridMan, WL=7005307944en_HK
dc.identifier.scopusauthoridCheung, MTW=38460909600en_HK
dc.identifier.scopusauthoridSun, RWY=26325835800en_HK
dc.identifier.scopusauthoridShu, YL=38461561900en_HK
dc.identifier.scopusauthoridLam, YW=7202563947en_HK
dc.identifier.scopusauthoridChe, CM=7102442791en_HK
dc.identifier.scopusauthoridLau, TC=7102222310en_HK

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