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Article: Drug discovery from Chinese medicine against neurodegeneration in Alzheimer's and vascular dementia

TitleDrug discovery from Chinese medicine against neurodegeneration in Alzheimer's and vascular dementia
Authors
KeywordsAbsence of side effects
Alzheimer disease
Asthma
Chinese medicine
Clinical trial (topic)
Issue Date2011
PublisherBioMed Central Ltd. The Journal's web site is located at http://www.cmjournal.org/home
Citation
Chinese Medicine, 2011, v. 6 How to Cite?
AbstractAlzheimer's disease and vascular dementia are two major diseases associated with dementia, which is common among the elderly. While the etiology of dementia is multi-factorial and complex, neurodegeneration may be the major cause of these two diseases. Effective drugs for treating dementia are still to be discovered. Current western pharmacological approaches against neurodegeneration in dementia develop symptom-relieving and disease-modifying drugs. Current integrative and holistic approaches of Chinese medicine to discovering drugs for neurodegeneration in dementia include (1) single molecules from the herbs, (2) standardized extracts from a single herb, and (3) herbal formula with definite composition. This article not only reviews the concept of dementia in western medicine and Chinese medicine but also evaluates the advantages and disadvantages of these approaches. © 2011 Ho et al; licensee BioMed Central Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/134345
ISSN
2015 Impact Factor: 1.58
2015 SCImago Journal Rankings: 0.655
PubMed Central ID
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorHo, YSen_HK
dc.contributor.authorSo, KFen_HK
dc.contributor.authorChang, RCen_HK
dc.date.accessioned2011-06-17T09:18:16Z-
dc.date.available2011-06-17T09:18:16Z-
dc.date.issued2011en_HK
dc.identifier.citationChinese Medicine, 2011, v. 6en_HK
dc.identifier.issn1749-8546en_HK
dc.identifier.urihttp://hdl.handle.net/10722/134345-
dc.description.abstractAlzheimer's disease and vascular dementia are two major diseases associated with dementia, which is common among the elderly. While the etiology of dementia is multi-factorial and complex, neurodegeneration may be the major cause of these two diseases. Effective drugs for treating dementia are still to be discovered. Current western pharmacological approaches against neurodegeneration in dementia develop symptom-relieving and disease-modifying drugs. Current integrative and holistic approaches of Chinese medicine to discovering drugs for neurodegeneration in dementia include (1) single molecules from the herbs, (2) standardized extracts from a single herb, and (3) herbal formula with definite composition. This article not only reviews the concept of dementia in western medicine and Chinese medicine but also evaluates the advantages and disadvantages of these approaches. © 2011 Ho et al; licensee BioMed Central Ltd.en_HK
dc.languageengen_US
dc.publisherBioMed Central Ltd. The Journal's web site is located at http://www.cmjournal.org/homeen_HK
dc.relation.ispartofChinese Medicineen_HK
dc.rightsChinese Medicine. Copyright © BioMed Central Ltd.-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subjectAbsence of side effects-
dc.subjectAlzheimer disease-
dc.subjectAsthma-
dc.subjectChinese medicine-
dc.subjectClinical trial (topic)-
dc.titleDrug discovery from Chinese medicine against neurodegeneration in Alzheimer's and vascular dementiaen_HK
dc.typeArticleen_HK
dc.identifier.emailSo, KF:hrmaskf@hkucc.hku.hken_HK
dc.identifier.emailChang, RC:rccchang@hkucc.hku.hken_HK
dc.identifier.authoritySo, KF=rp00329en_HK
dc.identifier.authorityChang, RC=rp00470en_HK
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1186/1749-8546-6-15en_HK
dc.identifier.pmid21513513-
dc.identifier.pmcidPMC3097009-
dc.identifier.scopuseid_2-s2.0-79955011062en_HK
dc.identifier.hkuros185641en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-79955011062&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume6en_HK
dc.identifier.isiWOS:000208722100015-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridHo, YS=14031513600en_HK
dc.identifier.scopusauthoridSo, KF=34668391300en_HK
dc.identifier.scopusauthoridChang, RC=7403713410en_HK

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