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Article: Drug discovery from Chinese medicine against neurodegeneration in Alzheimer's and vascular dementia
Title | Drug discovery from Chinese medicine against neurodegeneration in Alzheimer's and vascular dementia |
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Authors | |
Keywords | Absence of side effects Alzheimer disease Asthma Chinese medicine Clinical trial (topic) |
Issue Date | 2011 |
Publisher | BioMed Central Ltd. The Journal's web site is located at http://www.cmjournal.org/home |
Citation | Chinese Medicine, 2011, v. 6 How to Cite? |
Abstract | Alzheimer's disease and vascular dementia are two major diseases associated with dementia, which is common among the elderly. While the etiology of dementia is multi-factorial and complex, neurodegeneration may be the major cause of these two diseases. Effective drugs for treating dementia are still to be discovered. Current western pharmacological approaches against neurodegeneration in dementia develop symptom-relieving and disease-modifying drugs. Current integrative and holistic approaches of Chinese medicine to discovering drugs for neurodegeneration in dementia include (1) single molecules from the herbs, (2) standardized extracts from a single herb, and (3) herbal formula with definite composition. This article not only reviews the concept of dementia in western medicine and Chinese medicine but also evaluates the advantages and disadvantages of these approaches. © 2011 Ho et al; licensee BioMed Central Ltd. |
Persistent Identifier | http://hdl.handle.net/10722/134345 |
ISSN | 2023 Impact Factor: 5.3 2023 SCImago Journal Rankings: 0.877 |
PubMed Central ID | |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
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dc.contributor.author | Ho, YS | en_HK |
dc.contributor.author | So, KF | en_HK |
dc.contributor.author | Chang, RC | en_HK |
dc.date.accessioned | 2011-06-17T09:18:16Z | - |
dc.date.available | 2011-06-17T09:18:16Z | - |
dc.date.issued | 2011 | en_HK |
dc.identifier.citation | Chinese Medicine, 2011, v. 6 | en_HK |
dc.identifier.issn | 1749-8546 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/134345 | - |
dc.description.abstract | Alzheimer's disease and vascular dementia are two major diseases associated with dementia, which is common among the elderly. While the etiology of dementia is multi-factorial and complex, neurodegeneration may be the major cause of these two diseases. Effective drugs for treating dementia are still to be discovered. Current western pharmacological approaches against neurodegeneration in dementia develop symptom-relieving and disease-modifying drugs. Current integrative and holistic approaches of Chinese medicine to discovering drugs for neurodegeneration in dementia include (1) single molecules from the herbs, (2) standardized extracts from a single herb, and (3) herbal formula with definite composition. This article not only reviews the concept of dementia in western medicine and Chinese medicine but also evaluates the advantages and disadvantages of these approaches. © 2011 Ho et al; licensee BioMed Central Ltd. | en_HK |
dc.language | eng | en_US |
dc.publisher | BioMed Central Ltd. The Journal's web site is located at http://www.cmjournal.org/home | en_HK |
dc.relation.ispartof | Chinese Medicine | en_HK |
dc.rights | Chinese Medicine. Copyright © BioMed Central Ltd. | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.subject | Absence of side effects | - |
dc.subject | Alzheimer disease | - |
dc.subject | Asthma | - |
dc.subject | Chinese medicine | - |
dc.subject | Clinical trial (topic) | - |
dc.title | Drug discovery from Chinese medicine against neurodegeneration in Alzheimer's and vascular dementia | en_HK |
dc.type | Article | en_HK |
dc.identifier.email | So, KF:hrmaskf@hkucc.hku.hk | en_HK |
dc.identifier.email | Chang, RC:rccchang@hkucc.hku.hk | en_HK |
dc.identifier.authority | So, KF=rp00329 | en_HK |
dc.identifier.authority | Chang, RC=rp00470 | en_HK |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.1186/1749-8546-6-15 | en_HK |
dc.identifier.pmid | 21513513 | - |
dc.identifier.pmcid | PMC3097009 | - |
dc.identifier.scopus | eid_2-s2.0-79955011062 | en_HK |
dc.identifier.hkuros | 185641 | en_US |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-79955011062&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 6 | en_HK |
dc.identifier.isi | WOS:000208722100015 | - |
dc.publisher.place | United Kingdom | en_HK |
dc.identifier.scopusauthorid | Ho, YS=14031513600 | en_HK |
dc.identifier.scopusauthorid | So, KF=34668391300 | en_HK |
dc.identifier.scopusauthorid | Chang, RC=7403713410 | en_HK |
dc.identifier.issnl | 1749-8546 | - |