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- Publisher Website: 10.1586/ers.10.24
- Scopus: eid_2-s2.0-77953277486
- PMID: 20524916
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Article: The virulence of pandemic influenza A (H1N1) 2009: An epidemiological perspective on the case-fatality ratio
Title | The virulence of pandemic influenza A (H1N1) 2009: An epidemiological perspective on the case-fatality ratio |
---|---|
Authors | |
Keywords | References (52) View In Table Layout |
Issue Date | 2010 |
Publisher | Expert Reviews Ltd. The Journal's web site is located at http://www.future-drugs.com/page/journal/ers/teaser |
Citation | Expert Review Of Respiratory Medicine, 2010, v. 4 n. 3, p. 329-338 How to Cite? |
Abstract | When the pandemic influenza A (H1N1) 2009 virus emerged, one of the early priorities was to estimate its virulence. This is measured by the case-fatality ratio (CFR), the proportion of deaths from influenza among the total number of cases. Epidemiological studies in the very early stages of the pandemic estimated the confirmed CFR (cCFR), using confirmed cases as the denominator, to be approximately 0.5%. However, later studies estimated the symptomatic CFR (sCFR) as approximately 0.05% of all medically attended symptomatic cases. Although subjective, the virulence of influenza A (H1N1) 2009 can be perceived as mild. Further epidemiological investigations showed that both the cCFR and sCFR varied greatly by age and risk group. When assessing the efficacy of a specific intervention in reducing the risk of influenza-related death, particular care is required regarding the inclusion criteria and in matching age and underlying conditions between patients with, and without, the intervention. © 2010 Expert Reviews Ltd. |
Persistent Identifier | http://hdl.handle.net/10722/134197 |
ISSN | 2023 Impact Factor: 2.9 2023 SCImago Journal Rankings: 0.915 |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Nishiura, H | en_HK |
dc.date.accessioned | 2011-06-13T07:20:46Z | - |
dc.date.available | 2011-06-13T07:20:46Z | - |
dc.date.issued | 2010 | en_HK |
dc.identifier.citation | Expert Review Of Respiratory Medicine, 2010, v. 4 n. 3, p. 329-338 | en_HK |
dc.identifier.issn | 1747-6348 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/134197 | - |
dc.description.abstract | When the pandemic influenza A (H1N1) 2009 virus emerged, one of the early priorities was to estimate its virulence. This is measured by the case-fatality ratio (CFR), the proportion of deaths from influenza among the total number of cases. Epidemiological studies in the very early stages of the pandemic estimated the confirmed CFR (cCFR), using confirmed cases as the denominator, to be approximately 0.5%. However, later studies estimated the symptomatic CFR (sCFR) as approximately 0.05% of all medically attended symptomatic cases. Although subjective, the virulence of influenza A (H1N1) 2009 can be perceived as mild. Further epidemiological investigations showed that both the cCFR and sCFR varied greatly by age and risk group. When assessing the efficacy of a specific intervention in reducing the risk of influenza-related death, particular care is required regarding the inclusion criteria and in matching age and underlying conditions between patients with, and without, the intervention. © 2010 Expert Reviews Ltd. | en_HK |
dc.language | eng | en_US |
dc.publisher | Expert Reviews Ltd. The Journal's web site is located at http://www.future-drugs.com/page/journal/ers/teaser | en_HK |
dc.relation.ispartof | Expert Review of Respiratory Medicine | en_HK |
dc.subject | References (52) View In Table Layout | en_US |
dc.subject.mesh | Adolescent | en_HK |
dc.subject.mesh | Adult | en_HK |
dc.subject.mesh | Age Distribution | en_HK |
dc.subject.mesh | Age Factors | en_HK |
dc.subject.mesh | Aged | en_HK |
dc.subject.mesh | Child | en_HK |
dc.subject.mesh | Child, Preschool | en_HK |
dc.subject.mesh | Comorbidity | en_HK |
dc.subject.mesh | Disease Outbreaks - history | en_HK |
dc.subject.mesh | Health Policy | en_HK |
dc.subject.mesh | History, 20th Century | en_HK |
dc.subject.mesh | Humans | en_HK |
dc.subject.mesh | Infant | en_HK |
dc.subject.mesh | Infant, Newborn | en_HK |
dc.subject.mesh | Influenza A Virus, H1N1 Subtype - pathogenicity | en_HK |
dc.subject.mesh | Influenza, Human - epidemiology - history - mortality - virology | en_HK |
dc.subject.mesh | Middle Aged | en_HK |
dc.subject.mesh | Risk Assessment | en_HK |
dc.subject.mesh | Risk Factors | en_HK |
dc.subject.mesh | Severity of Illness Index | en_HK |
dc.subject.mesh | Time Factors | en_HK |
dc.subject.mesh | Virulence | en_HK |
dc.subject.mesh | Young Adult | en_HK |
dc.title | The virulence of pandemic influenza A (H1N1) 2009: An epidemiological perspective on the case-fatality ratio | en_HK |
dc.type | Article | en_HK |
dc.identifier.email | Nishiura, H:nishiura@hku.hk | en_HK |
dc.identifier.authority | Nishiura, H=rp01488 | en_HK |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1586/ers.10.24 | en_HK |
dc.identifier.pmid | 20524916 | - |
dc.identifier.scopus | eid_2-s2.0-77953277486 | en_HK |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-77953277486&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 4 | en_HK |
dc.identifier.issue | 3 | en_HK |
dc.identifier.spage | 329 | en_HK |
dc.identifier.epage | 338 | en_HK |
dc.publisher.place | United Kingdom | en_HK |
dc.identifier.scopusauthorid | Nishiura, H=7005501836 | en_HK |
dc.identifier.citeulike | 8407699 | - |
dc.identifier.issnl | 1747-6348 | - |