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Article: The virulence of pandemic influenza A (H1N1) 2009: An epidemiological perspective on the case-fatality ratio

TitleThe virulence of pandemic influenza A (H1N1) 2009: An epidemiological perspective on the case-fatality ratio
Authors
KeywordsReferences (52) View In Table Layout
Issue Date2010
PublisherExpert Reviews Ltd. The Journal's web site is located at http://www.future-drugs.com/page/journal/ers/teaser
Citation
Expert Review Of Respiratory Medicine, 2010, v. 4 n. 3, p. 329-338 How to Cite?
AbstractWhen the pandemic influenza A (H1N1) 2009 virus emerged, one of the early priorities was to estimate its virulence. This is measured by the case-fatality ratio (CFR), the proportion of deaths from influenza among the total number of cases. Epidemiological studies in the very early stages of the pandemic estimated the confirmed CFR (cCFR), using confirmed cases as the denominator, to be approximately 0.5%. However, later studies estimated the symptomatic CFR (sCFR) as approximately 0.05% of all medically attended symptomatic cases. Although subjective, the virulence of influenza A (H1N1) 2009 can be perceived as mild. Further epidemiological investigations showed that both the cCFR and sCFR varied greatly by age and risk group. When assessing the efficacy of a specific intervention in reducing the risk of influenza-related death, particular care is required regarding the inclusion criteria and in matching age and underlying conditions between patients with, and without, the intervention. © 2010 Expert Reviews Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/134197
ISSN
2015 Impact Factor: 2.176
2015 SCImago Journal Rankings: 0.720
References

 

DC FieldValueLanguage
dc.contributor.authorNishiura, Hen_HK
dc.date.accessioned2011-06-13T07:20:46Z-
dc.date.available2011-06-13T07:20:46Z-
dc.date.issued2010en_HK
dc.identifier.citationExpert Review Of Respiratory Medicine, 2010, v. 4 n. 3, p. 329-338en_HK
dc.identifier.issn1747-6348en_HK
dc.identifier.urihttp://hdl.handle.net/10722/134197-
dc.description.abstractWhen the pandemic influenza A (H1N1) 2009 virus emerged, one of the early priorities was to estimate its virulence. This is measured by the case-fatality ratio (CFR), the proportion of deaths from influenza among the total number of cases. Epidemiological studies in the very early stages of the pandemic estimated the confirmed CFR (cCFR), using confirmed cases as the denominator, to be approximately 0.5%. However, later studies estimated the symptomatic CFR (sCFR) as approximately 0.05% of all medically attended symptomatic cases. Although subjective, the virulence of influenza A (H1N1) 2009 can be perceived as mild. Further epidemiological investigations showed that both the cCFR and sCFR varied greatly by age and risk group. When assessing the efficacy of a specific intervention in reducing the risk of influenza-related death, particular care is required regarding the inclusion criteria and in matching age and underlying conditions between patients with, and without, the intervention. © 2010 Expert Reviews Ltd.en_HK
dc.languageengen_US
dc.publisherExpert Reviews Ltd. The Journal's web site is located at http://www.future-drugs.com/page/journal/ers/teaseren_HK
dc.relation.ispartofExpert Review of Respiratory Medicineen_HK
dc.subjectReferences (52) View In Table Layouten_US
dc.subject.meshAdolescenten_HK
dc.subject.meshAdulten_HK
dc.subject.meshAge Distributionen_HK
dc.subject.meshAge Factorsen_HK
dc.subject.meshAgeden_HK
dc.subject.meshChilden_HK
dc.subject.meshChild, Preschoolen_HK
dc.subject.meshComorbidityen_HK
dc.subject.meshDisease Outbreaks - historyen_HK
dc.subject.meshHealth Policyen_HK
dc.subject.meshHistory, 20th Centuryen_HK
dc.subject.meshHumansen_HK
dc.subject.meshInfanten_HK
dc.subject.meshInfant, Newbornen_HK
dc.subject.meshInfluenza A Virus, H1N1 Subtype - pathogenicityen_HK
dc.subject.meshInfluenza, Human - epidemiology - history - mortality - virologyen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshRisk Assessmenten_HK
dc.subject.meshRisk Factorsen_HK
dc.subject.meshSeverity of Illness Indexen_HK
dc.subject.meshTime Factorsen_HK
dc.subject.meshVirulenceen_HK
dc.subject.meshYoung Adulten_HK
dc.titleThe virulence of pandemic influenza A (H1N1) 2009: An epidemiological perspective on the case-fatality ratioen_HK
dc.typeArticleen_HK
dc.identifier.emailNishiura, H:nishiura@hku.hken_HK
dc.identifier.authorityNishiura, H=rp01488en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1586/ers.10.24en_HK
dc.identifier.pmid20524916-
dc.identifier.scopuseid_2-s2.0-77953277486en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-77953277486&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume4en_HK
dc.identifier.issue3en_HK
dc.identifier.spage329en_HK
dc.identifier.epage338en_HK
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridNishiura, H=7005501836en_HK
dc.identifier.citeulike8407699-

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