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Article: Echocardiography and non-invasive imaging in cardiac resynchronization therapy

TitleEchocardiography and non-invasive imaging in cardiac resynchronization therapy
Authors
Issue Date2010
PublisherEdizioni Minerva Medica
Citation
Minerva Cardioangiologica, 2010, v. 58 n. 3, p. 313-332 How to Cite?
AbstractThe beneficial effects of cardiac resynchronization therapy (CRT) on morbidity and mortality in advanced heart failure patients have been extensively demonstrated. However, previous single- and multicenter studies demonstrated that approximately 30-40% of CRT patients do not show significant clinical improvement or LV reverse remodeling despite fulfilling current inclusion criteria. In search of novel indices that may help to improve the selection of responders to CRT, non-invasive multimodality imaging has provided further insight into the mechanisms underlying CRT response. LV dyssynchrony, extent and location of myocardial scar and LV lead position have shown to be independent determinants of CRT response. An integrated evaluation of these three pathophysiological mechanisms may provide a more accurate selection of heart failure patients who will benefit from CRT and may maximize the cost-effectiveness of this therapy. The present review article provides a critical appraisal of the role of multimodality imaging in the selection of heart failure patients who are candidates for CRT with special focus on the assessment of LV mechanical dyssynchrony, LV myocardial scar tissue extent and LV lead position.
Persistent Identifierhttp://hdl.handle.net/10722/134132
ISSN
2015 Impact Factor: 0.752
2015 SCImago Journal Rankings: 0.399
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorDelgado, Ven_HK
dc.contributor.authorMooyaart, EAQen_HK
dc.contributor.authorNg, ACTen_HK
dc.contributor.authorAuger, Den_HK
dc.contributor.authorBertini, Men_HK
dc.contributor.authorVan Bommel, RJen_HK
dc.contributor.authorYiu, KHen_HK
dc.contributor.authorEwe, SHen_HK
dc.contributor.authorWitkowski, TGen_HK
dc.contributor.authorAjmone Marsan, Nen_HK
dc.contributor.authorSchuijf, JDen_HK
dc.contributor.authorVan Der Wall, EEen_HK
dc.contributor.authorSchalij, MJen_HK
dc.contributor.authorBax, JJen_HK
dc.date.accessioned2011-06-13T07:19:58Z-
dc.date.available2011-06-13T07:19:58Z-
dc.date.issued2010en_HK
dc.identifier.citationMinerva Cardioangiologica, 2010, v. 58 n. 3, p. 313-332en_HK
dc.identifier.issn0026-4725en_HK
dc.identifier.urihttp://hdl.handle.net/10722/134132-
dc.description.abstractThe beneficial effects of cardiac resynchronization therapy (CRT) on morbidity and mortality in advanced heart failure patients have been extensively demonstrated. However, previous single- and multicenter studies demonstrated that approximately 30-40% of CRT patients do not show significant clinical improvement or LV reverse remodeling despite fulfilling current inclusion criteria. In search of novel indices that may help to improve the selection of responders to CRT, non-invasive multimodality imaging has provided further insight into the mechanisms underlying CRT response. LV dyssynchrony, extent and location of myocardial scar and LV lead position have shown to be independent determinants of CRT response. An integrated evaluation of these three pathophysiological mechanisms may provide a more accurate selection of heart failure patients who will benefit from CRT and may maximize the cost-effectiveness of this therapy. The present review article provides a critical appraisal of the role of multimodality imaging in the selection of heart failure patients who are candidates for CRT with special focus on the assessment of LV mechanical dyssynchrony, LV myocardial scar tissue extent and LV lead position.en_HK
dc.languageengen_US
dc.publisherEdizioni Minerva Medicaen_US
dc.relation.ispartofMinerva Cardioangiologicaen_HK
dc.subject.meshArrhythmias, Cardiac - diagnosis - etiology - therapy - ultrasonographyen_HK
dc.subject.meshCardiac Resynchronization Therapy - methodsen_HK
dc.subject.meshCardiac-Gated Single-Photon Emission Computer-Assisted Tomographyen_HK
dc.subject.meshCardiomyopathies - diagnosisen_HK
dc.subject.meshCicatrix - diagnosisen_HK
dc.subject.meshHeart Failure - complicationsen_HK
dc.subject.meshHumansen_HK
dc.titleEchocardiography and non-invasive imaging in cardiac resynchronization therapyen_HK
dc.typeArticleen_HK
dc.identifier.emailYiu, KH:khkyiu@hku.hken_HK
dc.identifier.authorityYiu, KH=rp01490en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid20485238-
dc.identifier.scopuseid_2-s2.0-77957743642en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-77957743642&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume58en_HK
dc.identifier.issue3en_HK
dc.identifier.spage313en_HK
dc.identifier.epage332en_HK
dc.identifier.isiWOS:000208659600004-
dc.publisher.placeItalyen_HK
dc.identifier.scopusauthoridDelgado, V=24172709900en_HK
dc.identifier.scopusauthoridMooyaart, EAQ=15020989800en_HK
dc.identifier.scopusauthoridNg, ACT=15726084000en_HK
dc.identifier.scopusauthoridAuger, D=35723808000en_HK
dc.identifier.scopusauthoridBertini, M=22033600300en_HK
dc.identifier.scopusauthoridVan Bommel, RJ=24172817900en_HK
dc.identifier.scopusauthoridYiu, KH=35172267800en_HK
dc.identifier.scopusauthoridEwe, SH=23993827400en_HK
dc.identifier.scopusauthoridWitkowski, TG=7003737196en_HK
dc.identifier.scopusauthoridAjmone Marsan, N=17343204700en_HK
dc.identifier.scopusauthoridSchuijf, JD=6602555819en_HK
dc.identifier.scopusauthoridVan Der Wall, EE=7101764510en_HK
dc.identifier.scopusauthoridSchalij, MJ=7007083597en_HK
dc.identifier.scopusauthoridBax, JJ=35379683700en_HK

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