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Article: Targeting glutamate synthase for tuberculosis drug development

TitleTargeting glutamate synthase for tuberculosis drug development
Authors
Issue Date2011
PublisherHong Kong Medical Association. The Journal's web site is located at http://www.hkmj.org/index.html
Citation
Hong Kong Medical Journal, 2011, v. 17 n. Supp. 2, p. S32-34 How to Cite?
Abstract1. The Mycobacterium tuberculosis glutamate synthase consisting of alpha and beta subunits can be purified in a heterologous Escherichia coli expression system. 2. The beta subunit can be expressed in the soluble protein fraction under low temperature conditions. 3. The alpha subunit enters inclusion bodies in E coli but can be refolded and subsequently purified.
Persistent Identifierhttp://hdl.handle.net/10722/133579
ISSN
2015 Impact Factor: 0.887
2015 SCImago Journal Rankings: 0.279

 

DC FieldValueLanguage
dc.contributor.authorCheung, YWen_US
dc.contributor.authorTanner, JAen_US
dc.date.accessioned2011-05-24T02:11:13Z-
dc.date.available2011-05-24T02:11:13Z-
dc.date.issued2011en_US
dc.identifier.citationHong Kong Medical Journal, 2011, v. 17 n. Supp. 2, p. S32-34en_US
dc.identifier.issn1024-2708-
dc.identifier.urihttp://hdl.handle.net/10722/133579-
dc.description.abstract1. The Mycobacterium tuberculosis glutamate synthase consisting of alpha and beta subunits can be purified in a heterologous Escherichia coli expression system. 2. The beta subunit can be expressed in the soluble protein fraction under low temperature conditions. 3. The alpha subunit enters inclusion bodies in E coli but can be refolded and subsequently purified.-
dc.languageengen_US
dc.publisherHong Kong Medical Association. The Journal's web site is located at http://www.hkmj.org/index.html-
dc.relation.ispartofHong Kong Medical Journalen_US
dc.rightsHong Kong Medical Journal. Copyright © Hong Kong Medical Association.-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.titleTargeting glutamate synthase for tuberculosis drug developmenten_US
dc.typeArticleen_US
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1024-2708&volume=17&issue=Supp. 2&spage=S32&epage=34&date=2011&atitle=Targeting+glutamate+synthase+for+tuberculosis+drug+development-
dc.identifier.emailTanner, JA: jatanner@hku.hken_US
dc.identifier.authorityTanner, JA=rp00495en_US
dc.description.naturepublished_or_final_version-
dc.identifier.hkuros185116en_US
dc.identifier.volume17en_US
dc.identifier.issueSupp. 2-
dc.identifier.spageS32en_US
dc.identifier.epage34en_US

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