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Article: Application of a Nano-antimicrobial film to prevent ventilator-associated pneumonia: A pilot study

TitleApplication of a Nano-antimicrobial film to prevent ventilator-associated pneumonia: A pilot study
Authors
KeywordsBacterial colonization
Nanotechnology antimicrobial spray
Oral care
Ventilator-associated pneumonia
Issue Date2011
PublisherAcademic Journals. The Journal's web site is located at http://www.academicjournals.org/AJB/index.htm
Citation
African Journal Of Biotechnology, 2011, v. 10 n. 10, p. 1926-1931 How to Cite?
AbstractVentilator-associated pneumonia (VAP) is one of the most common hospital-associated infections and has accounted for approximately 15% of all hospital-associated infections. In 76% of the VAP cases, the same bacteria colonize the oral cavity and lungs. Oral care interventions may play a role in the prevention of VAP, yet more than half of the hospitals do not have specific policies for the oral care of intubated patients. Oral cavity interlinks with respiratory tracts and digestive tracts. After surgery has been performed in these areas, aerobic and anaerobic bacteria frequently induce operative wound infections in teeth, gingiva and supporting tissues of the teeth and tonsils. This study investigates the effects of a nanotechnology antimicrobial spray (JUC) on the incidence of VAP. 320 patients diagnosed with VAP were randomly divided into treatment and control groups. After using chlorhexidine mouthrinse, the treatment group used a nanotechnology antimicrobial spray to the nose and mouth. The control group was given normal saline. The incidence rate of VAP was significantly lower in the treatment (8.38%) than control group (54.24%) (p<0.01). A physical antimicrobial film is formed on the surface of oral and nasal mucosa after using the JUC spray which effectively reduces the microbial colonization in the sprayed areas, thus reducing and delaying the incidence of VAP. © 2011 Academic Journals.
Persistent Identifierhttp://hdl.handle.net/10722/133569
ISSN
2014 SCImago Journal Rankings: 0.257
References

 

DC FieldValueLanguage
dc.contributor.authorLi, Wen_HK
dc.contributor.authorMa, Xen_HK
dc.contributor.authorPeng, Yen_HK
dc.contributor.authorCao, Jen_HK
dc.contributor.authorLoo, WTYen_HK
dc.contributor.authorHao, Len_HK
dc.contributor.authorCheung, MNBen_HK
dc.contributor.authorChow, LWCen_HK
dc.contributor.authorJin, LJen_HK
dc.date.accessioned2011-05-24T02:10:42Z-
dc.date.available2011-05-24T02:10:42Z-
dc.date.issued2011en_HK
dc.identifier.citationAfrican Journal Of Biotechnology, 2011, v. 10 n. 10, p. 1926-1931en_HK
dc.identifier.issn1684-5315en_HK
dc.identifier.urihttp://hdl.handle.net/10722/133569-
dc.description.abstractVentilator-associated pneumonia (VAP) is one of the most common hospital-associated infections and has accounted for approximately 15% of all hospital-associated infections. In 76% of the VAP cases, the same bacteria colonize the oral cavity and lungs. Oral care interventions may play a role in the prevention of VAP, yet more than half of the hospitals do not have specific policies for the oral care of intubated patients. Oral cavity interlinks with respiratory tracts and digestive tracts. After surgery has been performed in these areas, aerobic and anaerobic bacteria frequently induce operative wound infections in teeth, gingiva and supporting tissues of the teeth and tonsils. This study investigates the effects of a nanotechnology antimicrobial spray (JUC) on the incidence of VAP. 320 patients diagnosed with VAP were randomly divided into treatment and control groups. After using chlorhexidine mouthrinse, the treatment group used a nanotechnology antimicrobial spray to the nose and mouth. The control group was given normal saline. The incidence rate of VAP was significantly lower in the treatment (8.38%) than control group (54.24%) (p<0.01). A physical antimicrobial film is formed on the surface of oral and nasal mucosa after using the JUC spray which effectively reduces the microbial colonization in the sprayed areas, thus reducing and delaying the incidence of VAP. © 2011 Academic Journals.en_HK
dc.languageengen_US
dc.publisherAcademic Journals. The Journal's web site is located at http://www.academicjournals.org/AJB/index.htmen_HK
dc.relation.ispartofAfrican Journal of Biotechnologyen_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subjectBacterial colonizationen_HK
dc.subjectNanotechnology antimicrobial sprayen_HK
dc.subjectOral careen_HK
dc.subjectVentilator-associated pneumoniaen_HK
dc.titleApplication of a Nano-antimicrobial film to prevent ventilator-associated pneumonia: A pilot studyen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1684-5315&volume=10&issue=10&spage=1926&epage=1931&date=2011&atitle=Application+of+a+nano-antimicrobial+film+to+prevent+ventilator-associated+pneumonia:+A+pilot+study-
dc.identifier.emailJin, LJ:ljjin@hkucc.hku.hken_HK
dc.identifier.authorityJin, LJ=rp00028en_HK
dc.description.naturepublished_or_final_version-
dc.identifier.scopuseid_2-s2.0-79952640463en_HK
dc.identifier.hkuros185237en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-79952640463&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume10en_HK
dc.identifier.issue10en_HK
dc.identifier.spage1926en_HK
dc.identifier.epage1931en_HK
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridLi, W=43861279700en_HK
dc.identifier.scopusauthoridMa, X=43861554900en_HK
dc.identifier.scopusauthoridPeng, Y=43861787600en_HK
dc.identifier.scopusauthoridCao, J=43861068400en_HK
dc.identifier.scopusauthoridLoo, WTY=7003567474en_HK
dc.identifier.scopusauthoridHao, L=37016273300en_HK
dc.identifier.scopusauthoridCheung, MNB=7201897548en_HK
dc.identifier.scopusauthoridChow, LWC=34975216600en_HK
dc.identifier.scopusauthoridJin, LJ=7403328850en_HK

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