File Download
 
Links for fulltext
(May Require Subscription)
 
Supplementary

Article: Application of a Nano-antimicrobial film to prevent ventilator-associated pneumonia: A pilot study
  • Basic View
  • Metadata View
  • XML View
TitleApplication of a Nano-antimicrobial film to prevent ventilator-associated pneumonia: A pilot study
 
AuthorsLi, W1
Ma, X1
Peng, Y1
Cao, J1
Loo, WTY2 2 3
Hao, L4
Cheung, MNB3
Chow, LWC3
Jin, LJ2
 
KeywordsBacterial colonization
Nanotechnology antimicrobial spray
Oral care
Ventilator-associated pneumonia
 
Issue Date2011
 
PublisherAcademic Journals. The Journal's web site is located at http://www.academicjournals.org/AJB/index.htm
 
CitationAfrican Journal Of Biotechnology, 2011, v. 10 n. 10, p. 1926-1931 [How to Cite?]
 
AbstractVentilator-associated pneumonia (VAP) is one of the most common hospital-associated infections and has accounted for approximately 15% of all hospital-associated infections. In 76% of the VAP cases, the same bacteria colonize the oral cavity and lungs. Oral care interventions may play a role in the prevention of VAP, yet more than half of the hospitals do not have specific policies for the oral care of intubated patients. Oral cavity interlinks with respiratory tracts and digestive tracts. After surgery has been performed in these areas, aerobic and anaerobic bacteria frequently induce operative wound infections in teeth, gingiva and supporting tissues of the teeth and tonsils. This study investigates the effects of a nanotechnology antimicrobial spray (JUC) on the incidence of VAP. 320 patients diagnosed with VAP were randomly divided into treatment and control groups. After using chlorhexidine mouthrinse, the treatment group used a nanotechnology antimicrobial spray to the nose and mouth. The control group was given normal saline. The incidence rate of VAP was significantly lower in the treatment (8.38%) than control group (54.24%) (p<0.01). A physical antimicrobial film is formed on the surface of oral and nasal mucosa after using the JUC spray which effectively reduces the microbial colonization in the sprayed areas, thus reducing and delaying the incidence of VAP. © 2011 Academic Journals.
 
ISSN1684-5315
2012 SCImago Journal Rankings: 0.270
 
ReferencesReferences in Scopus
 
DC FieldValue
dc.contributor.authorLi, W
 
dc.contributor.authorMa, X
 
dc.contributor.authorPeng, Y
 
dc.contributor.authorCao, J
 
dc.contributor.authorLoo, WTY
 
dc.contributor.authorHao, L
 
dc.contributor.authorCheung, MNB
 
dc.contributor.authorChow, LWC
 
dc.contributor.authorJin, LJ
 
dc.date.accessioned2011-05-24T02:10:42Z
 
dc.date.available2011-05-24T02:10:42Z
 
dc.date.issued2011
 
dc.description.abstractVentilator-associated pneumonia (VAP) is one of the most common hospital-associated infections and has accounted for approximately 15% of all hospital-associated infections. In 76% of the VAP cases, the same bacteria colonize the oral cavity and lungs. Oral care interventions may play a role in the prevention of VAP, yet more than half of the hospitals do not have specific policies for the oral care of intubated patients. Oral cavity interlinks with respiratory tracts and digestive tracts. After surgery has been performed in these areas, aerobic and anaerobic bacteria frequently induce operative wound infections in teeth, gingiva and supporting tissues of the teeth and tonsils. This study investigates the effects of a nanotechnology antimicrobial spray (JUC) on the incidence of VAP. 320 patients diagnosed with VAP were randomly divided into treatment and control groups. After using chlorhexidine mouthrinse, the treatment group used a nanotechnology antimicrobial spray to the nose and mouth. The control group was given normal saline. The incidence rate of VAP was significantly lower in the treatment (8.38%) than control group (54.24%) (p<0.01). A physical antimicrobial film is formed on the surface of oral and nasal mucosa after using the JUC spray which effectively reduces the microbial colonization in the sprayed areas, thus reducing and delaying the incidence of VAP. © 2011 Academic Journals.
 
dc.description.naturepublished_or_final_version
 
dc.identifier.citationAfrican Journal Of Biotechnology, 2011, v. 10 n. 10, p. 1926-1931 [How to Cite?]
 
dc.identifier.epage1931
 
dc.identifier.hkuros185237
 
dc.identifier.issn1684-5315
2012 SCImago Journal Rankings: 0.270
 
dc.identifier.issue10
 
dc.identifier.openurl
 
dc.identifier.scopuseid_2-s2.0-79952640463
 
dc.identifier.spage1926
 
dc.identifier.urihttp://hdl.handle.net/10722/133569
 
dc.identifier.volume10
 
dc.languageeng
 
dc.publisherAcademic Journals. The Journal's web site is located at http://www.academicjournals.org/AJB/index.htm
 
dc.publisher.placeUnited States
 
dc.relation.ispartofAfrican Journal of Biotechnology
 
dc.relation.referencesReferences in Scopus
 
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License
 
dc.subjectBacterial colonization
 
dc.subjectNanotechnology antimicrobial spray
 
dc.subjectOral care
 
dc.subjectVentilator-associated pneumonia
 
dc.titleApplication of a Nano-antimicrobial film to prevent ventilator-associated pneumonia: A pilot study
 
dc.typeArticle
 
<?xml encoding="utf-8" version="1.0"?>
<item><contributor.author>Li, W</contributor.author>
<contributor.author>Ma, X</contributor.author>
<contributor.author>Peng, Y</contributor.author>
<contributor.author>Cao, J</contributor.author>
<contributor.author>Loo, WTY</contributor.author>
<contributor.author>Hao, L</contributor.author>
<contributor.author>Cheung, MNB</contributor.author>
<contributor.author>Chow, LWC</contributor.author>
<contributor.author>Jin, LJ</contributor.author>
<date.accessioned>2011-05-24T02:10:42Z</date.accessioned>
<date.available>2011-05-24T02:10:42Z</date.available>
<date.issued>2011</date.issued>
<identifier.citation>African Journal Of Biotechnology, 2011, v. 10 n. 10, p. 1926-1931</identifier.citation>
<identifier.issn>1684-5315</identifier.issn>
<identifier.uri>http://hdl.handle.net/10722/133569</identifier.uri>
<description.abstract>Ventilator-associated pneumonia (VAP) is one of the most common hospital-associated infections and has accounted for approximately 15% of all hospital-associated infections. In 76% of the VAP cases, the same bacteria colonize the oral cavity and lungs. Oral care interventions may play a role in the prevention of VAP, yet more than half of the hospitals do not have specific policies for the oral care of intubated patients. Oral cavity interlinks with respiratory tracts and digestive tracts. After surgery has been performed in these areas, aerobic and anaerobic bacteria frequently induce operative wound infections in teeth, gingiva and supporting tissues of the teeth and tonsils. This study investigates the effects of a nanotechnology antimicrobial spray (JUC) on the incidence of VAP. 320 patients diagnosed with VAP were randomly divided into treatment and control groups. After using chlorhexidine mouthrinse, the treatment group used a nanotechnology antimicrobial spray to the nose and mouth. The control group was given normal saline. The incidence rate of VAP was significantly lower in the treatment (8.38%) than control group (54.24%) (p&lt;0.01). A physical antimicrobial film is formed on the surface of oral and nasal mucosa after using the JUC spray which effectively reduces the microbial colonization in the sprayed areas, thus reducing and delaying the incidence of VAP. &#169; 2011 Academic Journals.</description.abstract>
<language>eng</language>
<publisher>Academic Journals. The Journal&apos;s web site is located at http://www.academicjournals.org/AJB/index.htm</publisher>
<relation.ispartof>African Journal of Biotechnology</relation.ispartof>
<rights>Creative Commons: Attribution 3.0 Hong Kong License</rights>
<subject>Bacterial colonization</subject>
<subject>Nanotechnology antimicrobial spray</subject>
<subject>Oral care</subject>
<subject>Ventilator-associated pneumonia</subject>
<title>Application of a Nano-antimicrobial film to prevent ventilator-associated pneumonia: A pilot study</title>
<type>Article</type>
<identifier.openurl>http://library.hku.hk:4550/resserv?sid=HKU:IR&amp;issn=1684-5315&amp;volume=10&amp;issue=10&amp;spage=1926&amp;epage=1931&amp;date=2011&amp;atitle=Application+of+a+nano-antimicrobial+film+to+prevent+ventilator-associated+pneumonia:+A+pilot+study</identifier.openurl>
<description.nature>published_or_final_version</description.nature>
<identifier.scopus>eid_2-s2.0-79952640463</identifier.scopus>
<identifier.hkuros>185237</identifier.hkuros>
<relation.references>http://www.scopus.com/mlt/select.url?eid=2-s2.0-79952640463&amp;selection=ref&amp;src=s&amp;origin=recordpage</relation.references>
<identifier.volume>10</identifier.volume>
<identifier.issue>10</identifier.issue>
<identifier.spage>1926</identifier.spage>
<identifier.epage>1931</identifier.epage>
<publisher.place>United States</publisher.place>
<bitstream.url>http://hub.hku.hk/bitstream/10722/133569/1/Content.pdf</bitstream.url>
</item>
Author Affiliations
  1. Jinan University, School of Medicine
  2. The University of Hong Kong
  3. UNIMED Medical Institute and Organisation for Oncology and Translational Research
  4. Sichuan University