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Conference Paper: Rate-dependent block of hkv1.5 channels and the molecular determinant by the natural flavone acacetin
Title | Rate-dependent block of hkv1.5 channels and the molecular determinant by the natural flavone acacetin |
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Authors | |
Keywords | Cardiovascular disease |
Issue Date | 2010 |
Publisher | Hong Kong College of Cardiology. The Journal's web site is located at http://www.hkcchk.com/journals.php#3 |
Citation | The 14th Annual Scientific Meetingof the Institute of Cardiovascular Science and Medicine, Hong Kong, China, 18 December 2010. In Journal of the Hong Kong College of Cardiology, 2010, v. 18 n. 2, p. 78, abstract no. P25 How to Cite? |
Abstract | We have recently demonstrated that the natural flavone acacetin is an atrialselective compound that inhibits ultra-rapid delayed rectifier potassium current (IKur) and transient outward potassium current (Ito) in human atrial myocytes, and also acetylcholine-activated potassium current (IK.ACh). It increased atrial effective refractory period and effectively prevented atrial fibrillation (AF) in anesthetized dogs without prolonging QT interval of ECG. The present study was designed to ... |
Description | This journal issue is proceedings of ICSM 2010 Abstracts for Oral Communications |
Persistent Identifier | http://hdl.handle.net/10722/133391 |
ISSN | 2023 SCImago Journal Rankings: 0.115 |
DC Field | Value | Language |
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dc.contributor.author | Wu, H | en_US |
dc.contributor.author | Wu, W | en_US |
dc.contributor.author | Li, GR | en_US |
dc.date.accessioned | 2011-05-11T08:34:25Z | - |
dc.date.available | 2011-05-11T08:34:25Z | - |
dc.date.issued | 2010 | en_US |
dc.identifier.citation | The 14th Annual Scientific Meetingof the Institute of Cardiovascular Science and Medicine, Hong Kong, China, 18 December 2010. In Journal of the Hong Kong College of Cardiology, 2010, v. 18 n. 2, p. 78, abstract no. P25 | en_US |
dc.identifier.issn | 1027-7811 | - |
dc.identifier.uri | http://hdl.handle.net/10722/133391 | - |
dc.description | This journal issue is proceedings of ICSM 2010 | - |
dc.description | Abstracts for Oral Communications | - |
dc.description.abstract | We have recently demonstrated that the natural flavone acacetin is an atrialselective compound that inhibits ultra-rapid delayed rectifier potassium current (IKur) and transient outward potassium current (Ito) in human atrial myocytes, and also acetylcholine-activated potassium current (IK.ACh). It increased atrial effective refractory period and effectively prevented atrial fibrillation (AF) in anesthetized dogs without prolonging QT interval of ECG. The present study was designed to ... | - |
dc.language | eng | en_US |
dc.publisher | Hong Kong College of Cardiology. The Journal's web site is located at http://www.hkcchk.com/journals.php#3 | - |
dc.relation.ispartof | Journal of the Hong Kong College of Cardiology | en_US |
dc.subject | Cardiovascular disease | - |
dc.title | Rate-dependent block of hkv1.5 channels and the molecular determinant by the natural flavone acacetin | en_US |
dc.type | Conference_Paper | en_US |
dc.identifier.email | Wu, H: h0894109@hku.hk | en_US |
dc.identifier.email | Li, GR: grli@hkucc.hku.hk | - |
dc.identifier.authority | Li, GR=rp00476 | en_US |
dc.description.nature | link_to_OA_fulltext | - |
dc.identifier.hkuros | 184873 | en_US |
dc.identifier.volume | 18 | en_US |
dc.identifier.issue | 2 | en_US |
dc.identifier.spage | 78 | en_US |
dc.identifier.epage | 78 | en_US |
dc.publisher.place | Hong Kong | - |
dc.description.other | The 14th Annual Scientific Meetingof the Institute of Cardiovascular Science and Medicine, Hong Kong, China, 18 December 2010. In Journal of the Hong Kong College of Cardiology, 2010, v. 18 n. 2, p. 78, abstract no. P25 | - |
dc.identifier.issnl | 1027-7811 | - |