File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: The long-term effects of psychotherapy added to pharmacotherapy on morning to evening diurnal cortisol patterns in outpatients with major depression

TitleThe long-term effects of psychotherapy added to pharmacotherapy on morning to evening diurnal cortisol patterns in outpatients with major depression
Authors
KeywordsBody-mind-spirit therapy
Major depressive disorder
Pharmacotherapy
Psychotherapy
Salivary diurnal cortisol pattern
Issue Date2011
PublisherS Karger AG. The Journal's web site is located at http://www.karger.com/PPS
Citation
Psychotherapy And Psychosomatics, 2011, v. 80 n. 3, p. 166-172 How to Cite?
AbstractBackground: Psychotherapy added to pharmacotherapy results in greater improvement in clinical outcomes than does pharmacotherapy alone. However, few studies examined how psychotherapy coupled with pharmacotherapy could produce a long-term protective effect by improving the psychobiological stress response. Methods: The researchers recruited 63 subjects with major depressive disorder (MDD) in an outpatient department of psychiatry at a general hospital. The randomly assigned subjects formed 2 groups: 29 in combined therapy (COMB) and 34 in monotherapy (MT). The COMB included 8 weekly body-mind-spirit group psychotherapy sessions added to pharmacotherapy. MT consisted of pharmacotherapy only. The outcome measures, collected at the subjects' homes, included the Beck Depression Inventory II (BDI-II), the State Trait Anxiety Inventory (STAI) and salivary cortisol on awakening, 45 min after awakening, and at 12.00, 17.00 and 21.00 h. Evaluation of outcome measures was at baseline condition, and at months 2 (end of additional psychotherapy), 5 and 8. Results: While the decreases in symptoms of depression were similar between COMB and MT (p > 0.05), the reductions in anxiety state were greater in COMB than in MT during the 8-month follow-up (p < 0.05). A steeper diurnal cortisol pattern more likely occurred in COMB than in MT in the 3 follow-up periods (p < 0.05, p <0.001 and p < 0.01). Conclusions: The superior outcomes of group psychotherapy added to pharmacotherapy for MDD outpatients could relate to decreasing the anxiety state and to producing long-term impacts on positive stress endocrine outcomes seen as a steeper diurnal cortisol pattern. © 2011 S. Karger AG, Basel.
Persistent Identifierhttp://hdl.handle.net/10722/133345
ISSN
2015 Impact Factor: 7.632
2015 SCImago Journal Rankings: 2.657
ISI Accession Number ID
Funding AgencyGrant Number
National Science CouncilNSC 95-2314-B-038-045-MY2
Funding Information:

This study was supported by a grant from the National Science Council (NSC 95-2314-B-038-045-MY2).

References

 

DC FieldValueLanguage
dc.contributor.authorHsiao, FHen_HK
dc.contributor.authorJow, GMen_HK
dc.contributor.authorLai, YMen_HK
dc.contributor.authorChen, YTen_HK
dc.contributor.authorWang, KCen_HK
dc.contributor.authorNg, SMen_HK
dc.contributor.authorHo, RTHen_HK
dc.contributor.authorChan, CLWen_HK
dc.contributor.authorYang, TTen_HK
dc.date.accessioned2011-05-11T08:32:32Z-
dc.date.available2011-05-11T08:32:32Z-
dc.date.issued2011en_HK
dc.identifier.citationPsychotherapy And Psychosomatics, 2011, v. 80 n. 3, p. 166-172en_HK
dc.identifier.issn0033-3190en_HK
dc.identifier.urihttp://hdl.handle.net/10722/133345-
dc.description.abstractBackground: Psychotherapy added to pharmacotherapy results in greater improvement in clinical outcomes than does pharmacotherapy alone. However, few studies examined how psychotherapy coupled with pharmacotherapy could produce a long-term protective effect by improving the psychobiological stress response. Methods: The researchers recruited 63 subjects with major depressive disorder (MDD) in an outpatient department of psychiatry at a general hospital. The randomly assigned subjects formed 2 groups: 29 in combined therapy (COMB) and 34 in monotherapy (MT). The COMB included 8 weekly body-mind-spirit group psychotherapy sessions added to pharmacotherapy. MT consisted of pharmacotherapy only. The outcome measures, collected at the subjects' homes, included the Beck Depression Inventory II (BDI-II), the State Trait Anxiety Inventory (STAI) and salivary cortisol on awakening, 45 min after awakening, and at 12.00, 17.00 and 21.00 h. Evaluation of outcome measures was at baseline condition, and at months 2 (end of additional psychotherapy), 5 and 8. Results: While the decreases in symptoms of depression were similar between COMB and MT (p > 0.05), the reductions in anxiety state were greater in COMB than in MT during the 8-month follow-up (p < 0.05). A steeper diurnal cortisol pattern more likely occurred in COMB than in MT in the 3 follow-up periods (p < 0.05, p <0.001 and p < 0.01). Conclusions: The superior outcomes of group psychotherapy added to pharmacotherapy for MDD outpatients could relate to decreasing the anxiety state and to producing long-term impacts on positive stress endocrine outcomes seen as a steeper diurnal cortisol pattern. © 2011 S. Karger AG, Basel.en_HK
dc.languageengen_US
dc.publisherS Karger AG. The Journal's web site is located at http://www.karger.com/PPSen_HK
dc.relation.ispartofPsychotherapy and Psychosomaticsen_HK
dc.subjectBody-mind-spirit therapyen_HK
dc.subjectMajor depressive disorderen_HK
dc.subjectPharmacotherapyen_HK
dc.subjectPsychotherapyen_HK
dc.subjectSalivary diurnal cortisol patternen_HK
dc.titleThe long-term effects of psychotherapy added to pharmacotherapy on morning to evening diurnal cortisol patterns in outpatients with major depressionen_HK
dc.typeArticleen_HK
dc.identifier.emailNg, SM: ngsiuman@hku.hken_HK
dc.identifier.emailHo, RTH: tinho@hku.hken_HK
dc.identifier.emailChan, CLW: cecichan@hku.hken_HK
dc.identifier.authorityNg, SM=rp00611en_HK
dc.identifier.authorityHo, RTH=rp00497en_HK
dc.identifier.authorityChan, CLW=rp00579en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1159/000321558en_HK
dc.identifier.pmid21389753-
dc.identifier.scopuseid_2-s2.0-79952328191en_HK
dc.identifier.hkuros184893en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-79952328191&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume80en_HK
dc.identifier.issue3en_HK
dc.identifier.spage166en_HK
dc.identifier.epage172en_HK
dc.identifier.isiWOS:000289338800006-
dc.publisher.placeSwitzerlanden_HK
dc.identifier.scopusauthoridHsiao, FH=7006744649en_HK
dc.identifier.scopusauthoridJow, GM=6603159405en_HK
dc.identifier.scopusauthoridLai, YM=7401512146en_HK
dc.identifier.scopusauthoridChen, YT=49963217300en_HK
dc.identifier.scopusauthoridWang, KC=24598349100en_HK
dc.identifier.scopusauthoridNg, SM=7403358478en_HK
dc.identifier.scopusauthoridHo, RTH=8620896500en_HK
dc.identifier.scopusauthoridChan, CLW=35274549700en_HK
dc.identifier.scopusauthoridYang, TT=10241889500en_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats