Article: Independent and combined associations of abdominal obesity and seated resting heart rate with type 2 diabetes among older Chinese: The Guangzhou Biobank Cohort Study
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- Publisher Website: 10.1002/dmrr.1178
- Scopus: eid_2-s2.0-79952129154
- PMID: 21309059
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| Title | Independent and combined associations of abdominal obesity and seated resting heart rate with type 2 diabetes among older Chinese: The Guangzhou Biobank Cohort Study |
|---|---|
| Authors | Ó Hartaigh, B3 Jiang, CQ2 Bosch, JA3 Zhang, WS2 Cheng, KK3 Lam, TH1 Thomas, GN3 |
| Keywords | Abdominal obesity Chinese Heart rate Type 2 diabetes |
| Issue Date | 2011 |
| Publisher | John Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/10009394 |
| Citation | Diabetes/Metabolism Research And Reviews, 2011, v. 27 n. 3, p. 298-306 [How to Cite?] DOI: http://dx.doi.org/10.1002/dmrr.1178 |
| Abstract | Background: Central obesity and poor physical fitness predict the development of type 2 diabetes and cardiovascular mortality among Caucasian populations. We studied the independent and combined effect of abdominal obesity and seated resting heart rate used as an indicator of physical fitness, on the presence of type 2 diabetes among 30 519 older residents of Guangzhou, Southern China. Methods: Participants were stratified into four groups, based on the Asian criteria for abdominal obesity (≥90/≥ 80 cm in men/women) and the 75% cut-off point for seated resting heart rate (≥83 beats per min). The association with type 2 diabetes was assessed using multivariable logistic regression. Results: A total of 3777 (12.7%) volunteers were diagnosed with type 2 diabetes, which was independently associated with seated resting heart rate and, in particular, increasing levels of abdominal obesity (p < 0.001). An odds ratio of 3.93 (95% confidence interval = 3.48-4.43) was identified for type 2 diabetes in participants who were obese with a seated resting heart rate ≥ 83 beats per min after adjusting for potential confounders. +Conclusions: Higher seated resting heart rate, a marker of poor physical fitness, independently doubles the risk of type 2 diabetes. The strength of this association is further increased when abdominal obesity is considered. © 2011 John Wiley & Sons, Ltd. |
| ISSN | 1520-7552 2011 Impact Factor: 3.373 2011 SCImago Journal Rankings: 0.274 |
| DOI | http://dx.doi.org/10.1002/dmrr.1178 |
| References | References in Scopus |
| dc.contributor.author | Ó Hartaigh, B | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| dc.contributor.author | Jiang, CQ | ||||||||||
| dc.contributor.author | Bosch, JA | ||||||||||
| dc.contributor.author | Zhang, WS | ||||||||||
| dc.contributor.author | Cheng, KK | ||||||||||
| dc.contributor.author | Lam, TH | ||||||||||
| dc.contributor.author | Thomas, GN | ||||||||||
| dc.date.accessioned | 2011-05-11T08:32:24Z | ||||||||||
| dc.date.available | 2011-05-11T08:32:24Z | ||||||||||
| dc.date.issued | 2011 | ||||||||||
| dc.description.abstract | Background: Central obesity and poor physical fitness predict the development of type 2 diabetes and cardiovascular mortality among Caucasian populations. We studied the independent and combined effect of abdominal obesity and seated resting heart rate used as an indicator of physical fitness, on the presence of type 2 diabetes among 30 519 older residents of Guangzhou, Southern China. Methods: Participants were stratified into four groups, based on the Asian criteria for abdominal obesity (≥90/≥ 80 cm in men/women) and the 75% cut-off point for seated resting heart rate (≥83 beats per min). The association with type 2 diabetes was assessed using multivariable logistic regression. Results: A total of 3777 (12.7%) volunteers were diagnosed with type 2 diabetes, which was independently associated with seated resting heart rate and, in particular, increasing levels of abdominal obesity (p < 0.001). An odds ratio of 3.93 (95% confidence interval = 3.48-4.43) was identified for type 2 diabetes in participants who were obese with a seated resting heart rate ≥ 83 beats per min after adjusting for potential confounders. +Conclusions: Higher seated resting heart rate, a marker of poor physical fitness, independently doubles the risk of type 2 diabetes. The strength of this association is further increased when abdominal obesity is considered. © 2011 John Wiley & Sons, Ltd. | ||||||||||
| dc.description.nature | Link_to_subscribed_fulltext | ||||||||||
| dc.identifier.citation | Diabetes/Metabolism Research And Reviews, 2011, v. 27 n. 3, p. 298-306 [How to Cite?] DOI: http://dx.doi.org/10.1002/dmrr.1178 | ||||||||||
| dc.identifier.doi | http://dx.doi.org/10.1002/dmrr.1178 | ||||||||||
| dc.identifier.epage | 306 | ||||||||||
| dc.identifier.hkuros | 185058 | ||||||||||
| dc.identifier.isi | WOS:000288034300012
Funding Information: The Guangzhou Biobank Cohort Study was funded by the University of Hong Kong Foundation for Educational Development and Research, Hong Kong; the Guangzhou Public Health Bureau and the Guangzhou Science and Technology Bureau, Guangzhou, China; and the University of Birmingham, UK. We thank the Guangzhou Health and Happiness Association for the Respectable Elders for recruiting the participants. The Guangzhou Biobank Cohort Study investigators include the Guangzhou Number 12 People's Hospital: W. S. Zhang, M. Cao, T. Zhu, B. Liu and C. Q. Jiang (Co-PI); the University of Hong Kong: C. M. Schooling, S. M. McGhee, R. F. Fielding, G. M. Leung and T. H. Lam (Co-PI) and the University of Birmingham: G. N. Thomas, P. Adab and K. K. Cheng (Co-PI). | ||||||||||
| dc.identifier.issn | 1520-7552 2011 Impact Factor: 3.373 2011 SCImago Journal Rankings: 0.274 | ||||||||||
| dc.identifier.issue | 3 | ||||||||||
| dc.identifier.openurl | | ||||||||||
| dc.identifier.pmid | 21309059 | ||||||||||
| dc.identifier.scopus | eid_2-s2.0-79952129154 | ||||||||||
| dc.identifier.spage | 298 | ||||||||||
| dc.identifier.uri | http://hdl.handle.net/10722/133344 | ||||||||||
| dc.identifier.volume | 27 | ||||||||||
| dc.language | eng | ||||||||||
| dc.publisher | John Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/10009394 | ||||||||||
| dc.publisher.place | United Kingdom | ||||||||||
| dc.relation.ispartof | Diabetes/Metabolism Research and Reviews | ||||||||||
| dc.relation.references | References in Scopus | ||||||||||
| dc.rights | Diabetes - Metabolism: Research and Reviews. Copyright © John Wiley & Sons Ltd. | ||||||||||
| dc.subject | Abdominal obesity | ||||||||||
| dc.subject | Chinese | ||||||||||
| dc.subject | Heart rate | ||||||||||
| dc.subject | Type 2 diabetes | ||||||||||
| dc.title | Independent and combined associations of abdominal obesity and seated resting heart rate with type 2 diabetes among older Chinese: The Guangzhou Biobank Cohort Study | ||||||||||
| dc.type | Article |
Author Affiliations
- The University of Hong Kong
- Guangzhou No. 12 Hospital
- University of Birmingham