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Article: The association between depressive symptoms and mortality among Chinese elderly: A Hong Kong cohort study

TitleThe association between depressive symptoms and mortality among Chinese elderly: A Hong Kong cohort study
Authors
KeywordsDepressive symptoms
Geriatric Depression Scale
Mortality
Suicide
Issue Date2011
PublisherOxford University Press. The Journal's web site is located at http://biomed.gerontologyjournals.org/
Citation
Journals Of Gerontology - Series A Biological Sciences And Medical Sciences, 2011, v. 66 A n. 4, p. 459-466 How to Cite?
AbstractBackground: Increasingly, researchers have begun to explore the association between depression and mortality. The current study examined the association between depressive symptoms and all-cause and cause-specific mortality in Chinese older people. Further to examine whether any associations were similar by sex and health status. Methods: We used the Chinese version of the 15-item Geriatric Depression Scale to measure depressive symptoms (Geriatric Depression Scale score > 8) and Cox regression to examine the association with all-cause and cause-specific mortality in a population-based cohort study of all 56,088 enrollees, aged 65 years or older, from July 1998 to December 2000 at all 18 Elderly Health Centers of Department of Health of Hong Kong. The cohort was followed up for mortality till December 31, 2005. Results. Depressive symptoms were associated with all-cause mortality (hazard ratio 1.21, 95% confidence interval: 1.08-1.37) in men only (p value for sex interaction <.05) and with suicide mortality in men (hazard ratio 2.81, 95% confidence interval: 1.13-7.01) and women (hazard ratio 2.40, 95% confidence interval: 1.18-4.82) but not with other major causes of death after adjusting for age, education, monthly expenditure, smoking, alcohol drinking, physical activity, body mass index, health status, and self-rated health. The associations did not vary with health status. Conclusions. Depressive symptoms were associated with all-cause mortality in men and with suicide in both sexes. Randomized controlled trials concerning the effects of treatment of depression on mortality are needed to clarify the causal pathways. © The Author 2010. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/133340
ISSN
2015 Impact Factor: 5.476
2015 SCImago Journal Rankings: 2.675
ISI Accession Number ID
Funding AgencyGrant Number
Health Care & Promotion Fund Committee, Hong KongS111016
Funding Information:

This project was funded by grant S111016 from the Health Care & Promotion Fund Committee, Hong Kong.

References
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DC FieldValueLanguage
dc.contributor.authorSun, Wen_HK
dc.contributor.authorSchooling, CMen_HK
dc.contributor.authorChan, WMen_HK
dc.contributor.authorHo, KSen_HK
dc.contributor.authorLam, THen_HK
dc.date.accessioned2011-05-11T08:32:21Z-
dc.date.available2011-05-11T08:32:21Z-
dc.date.issued2011en_HK
dc.identifier.citationJournals Of Gerontology - Series A Biological Sciences And Medical Sciences, 2011, v. 66 A n. 4, p. 459-466en_HK
dc.identifier.issn1079-5006en_HK
dc.identifier.urihttp://hdl.handle.net/10722/133340-
dc.description.abstractBackground: Increasingly, researchers have begun to explore the association between depression and mortality. The current study examined the association between depressive symptoms and all-cause and cause-specific mortality in Chinese older people. Further to examine whether any associations were similar by sex and health status. Methods: We used the Chinese version of the 15-item Geriatric Depression Scale to measure depressive symptoms (Geriatric Depression Scale score > 8) and Cox regression to examine the association with all-cause and cause-specific mortality in a population-based cohort study of all 56,088 enrollees, aged 65 years or older, from July 1998 to December 2000 at all 18 Elderly Health Centers of Department of Health of Hong Kong. The cohort was followed up for mortality till December 31, 2005. Results. Depressive symptoms were associated with all-cause mortality (hazard ratio 1.21, 95% confidence interval: 1.08-1.37) in men only (p value for sex interaction <.05) and with suicide mortality in men (hazard ratio 2.81, 95% confidence interval: 1.13-7.01) and women (hazard ratio 2.40, 95% confidence interval: 1.18-4.82) but not with other major causes of death after adjusting for age, education, monthly expenditure, smoking, alcohol drinking, physical activity, body mass index, health status, and self-rated health. The associations did not vary with health status. Conclusions. Depressive symptoms were associated with all-cause mortality in men and with suicide in both sexes. Randomized controlled trials concerning the effects of treatment of depression on mortality are needed to clarify the causal pathways. © The Author 2010. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved.en_HK
dc.languageengen_US
dc.publisherOxford University Press. The Journal's web site is located at http://biomed.gerontologyjournals.org/en_HK
dc.relation.ispartofJournals of Gerontology - Series A Biological Sciences and Medical Sciencesen_HK
dc.subjectDepressive symptomsen_HK
dc.subjectGeriatric Depression Scaleen_HK
dc.subjectMortalityen_HK
dc.subjectSuicideen_HK
dc.titleThe association between depressive symptoms and mortality among Chinese elderly: A Hong Kong cohort studyen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1079-5006&volume=66A&issue=4&spage=459&epage=466&date=2011&atitle=The+association+between+depressive+symptoms+and+mortality+among+Chinese+elderly:+a+Hong+Kong+cohort+study-
dc.identifier.emailSchooling, CM:cms1@hkucc.hku.hken_HK
dc.identifier.emailLam, TH:hrmrlth@hkucc.hku.hken_HK
dc.identifier.authoritySchooling, CM=rp00504en_HK
dc.identifier.authorityLam, TH=rp00326en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1093/gerona/glq206en_HK
dc.identifier.pmid21106705-
dc.identifier.scopuseid_2-s2.0-79957810566en_HK
dc.identifier.hkuros184992en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-79957810566&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume66 Aen_HK
dc.identifier.issue4en_HK
dc.identifier.spage459en_HK
dc.identifier.epage466en_HK
dc.identifier.isiWOS:000288836600012-
dc.publisher.placeUnited Statesen_HK
dc.relation.projectA prospective study of major risk factors and mortality in the clients of the Hong Kong elderly health services-
dc.identifier.scopusauthoridSun, W=18635452400en_HK
dc.identifier.scopusauthoridSchooling, CM=12808565000en_HK
dc.identifier.scopusauthoridChan, WM=7403914485en_HK
dc.identifier.scopusauthoridHo, KS=7403581605en_HK
dc.identifier.scopusauthoridLam, TH=7202522876en_HK

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