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Article: Databases for pediatric medicine research in Europe - Assessment and critical appraisal

TitleDatabases for pediatric medicine research in Europe - Assessment and critical appraisal
Authors
KeywordsDatabases
Drug safety
Drug utilization
Pediatric
Issue Date2008
PublisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/5669
Citation
Pharmacoepidemiology And Drug Safety, 2008, v. 17 n. 12, p. 1155-1167 How to Cite?
AbstractPurpose: To identify and describe European health care databases that can be used for pediatric pharmacoepidemiological research. Methods: A web-based survey was conducted among all European databases that were listed on the website of the International Society of Pharmacoepidemiology (ISPE)and/or known by an expert group. The survey comprised of questions regarding (a) the nature of the database, (b) database size, (c) demographic, clinical and drug related data provided, (d) cost, and (e) accessibility of the database. Results: A total of 25 data sources from 12 European countries were identified and invited to participate in the survey. Responses were obtained from 21 (84%) databases located in 10 different European countries. Seventeen databases were included in the assessment comprising a total of at least 9 million children aged 0-18 years. The majority of databases are based on outpatient data and all keep either prescription or drug dispensing data. Ten databases are based on electronic patient records from primary care physicians and five databases are predominantly claims oriented. Three databases do not belong to either of the above mentioned categories. Almost all of the databases can be used for pediatric drug utilization studies. For drug safety studies it is more appropriate to use electronic patient record databases because of the available clinical information and the potential to obtain additional information. Conclusions: There are many European healthcare databases providing an enormous potential for pediatric pharmacoepidemiological research. Future research should focus on methods to bring data from different databases together to use the full capacity effectively. Copyright © 2008 John Wiley & Sons, Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/132928
ISSN
2015 Impact Factor: 2.908
2015 SCImago Journal Rankings: 1.804
ISI Accession Number ID
Funding AgencyGrant Number
European Community's 6th framework programmeLSHB-CT-2005-005216
Funding Information:

The project has been funded under the European Community's 6th framework programme project number LSHB-CT-2005-005216: TEDDY (Task force in Europe for Drug Development for the Young).

References

 

DC FieldValueLanguage
dc.contributor.authorNeubert, Aen_HK
dc.contributor.authorSturkenboom, MCJMen_HK
dc.contributor.authorMurray, MLen_HK
dc.contributor.authorVerhamme, KMCen_HK
dc.contributor.authorNicolosi, Aen_HK
dc.contributor.authorGiaquinto, Cen_HK
dc.contributor.authorCeci, Aen_HK
dc.contributor.authorWong, ICKen_HK
dc.date.accessioned2011-04-04T07:58:02Z-
dc.date.available2011-04-04T07:58:02Z-
dc.date.issued2008en_HK
dc.identifier.citationPharmacoepidemiology And Drug Safety, 2008, v. 17 n. 12, p. 1155-1167en_HK
dc.identifier.issn1053-8569en_HK
dc.identifier.urihttp://hdl.handle.net/10722/132928-
dc.description.abstractPurpose: To identify and describe European health care databases that can be used for pediatric pharmacoepidemiological research. Methods: A web-based survey was conducted among all European databases that were listed on the website of the International Society of Pharmacoepidemiology (ISPE)and/or known by an expert group. The survey comprised of questions regarding (a) the nature of the database, (b) database size, (c) demographic, clinical and drug related data provided, (d) cost, and (e) accessibility of the database. Results: A total of 25 data sources from 12 European countries were identified and invited to participate in the survey. Responses were obtained from 21 (84%) databases located in 10 different European countries. Seventeen databases were included in the assessment comprising a total of at least 9 million children aged 0-18 years. The majority of databases are based on outpatient data and all keep either prescription or drug dispensing data. Ten databases are based on electronic patient records from primary care physicians and five databases are predominantly claims oriented. Three databases do not belong to either of the above mentioned categories. Almost all of the databases can be used for pediatric drug utilization studies. For drug safety studies it is more appropriate to use electronic patient record databases because of the available clinical information and the potential to obtain additional information. Conclusions: There are many European healthcare databases providing an enormous potential for pediatric pharmacoepidemiological research. Future research should focus on methods to bring data from different databases together to use the full capacity effectively. Copyright © 2008 John Wiley & Sons, Ltd.en_HK
dc.languageengen_US
dc.publisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/5669en_HK
dc.relation.ispartofPharmacoepidemiology and Drug Safetyen_HK
dc.subjectDatabasesen_HK
dc.subjectDrug safetyen_HK
dc.subjectDrug utilizationen_HK
dc.subjectPediatricen_HK
dc.titleDatabases for pediatric medicine research in Europe - Assessment and critical appraisalen_HK
dc.typeArticleen_HK
dc.identifier.emailWong, ICK: wongick@hku.hken_HK
dc.identifier.authorityWong, ICK=rp01480en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1002/pds.1661en_HK
dc.identifier.pmid18979461en_HK
dc.identifier.scopuseid_2-s2.0-58149361632en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-58149361632&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume17en_HK
dc.identifier.issue12en_HK
dc.identifier.spage1155en_HK
dc.identifier.epage1167en_HK
dc.identifier.eissn1099-1557-
dc.identifier.isiWOS:000261912200004-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridNeubert, A=7003774960en_HK
dc.identifier.scopusauthoridSturkenboom, MCJM=21743803900en_HK
dc.identifier.scopusauthoridMurray, ML=7403583537en_HK
dc.identifier.scopusauthoridVerhamme, KMC=6507849095en_HK
dc.identifier.scopusauthoridNicolosi, A=7006060070en_HK
dc.identifier.scopusauthoridGiaquinto, C=7006585659en_HK
dc.identifier.scopusauthoridCeci, A=7006836326en_HK
dc.identifier.scopusauthoridWong, ICK=7102513915en_HK
dc.identifier.citeulike7631437-

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