Article: The Asia-Pacific consensus on ulcerative colitis
| Title | The Asia-Pacific consensus on ulcerative colitis |
|---|---|
| Authors | Ooi, CJ1 Fock, KM10 Makharia, GK8 Goh, KL6 Ling, KL Hilmi, I6 Lim, WC11 Kelvin, T Gibson, PR4 Gearry, RB7 Ouyang, Q12 Sollano, J2 Manatsathit, S13 Rerknimitr, R5 Wei, SC3 Leung, WK14 De Silva, HJ9 Leong, RWL |
| Keywords | Chemicals And Cas Registry Numbers |
| Issue Date | 2010 |
| Publisher | Wiley-Blackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/JGH |
| Citation | Journal Of Gastroenterology And Hepatology, 2010, v. 25 n. 3, p. 453-468 [How to Cite?] DOI: http://dx.doi.org/10.1111/j.1440-1746.2010.06241.x |
| Abstract | Inflammatory bowel disease (IBD) is increasing in many parts of the Asia-Pacific region. There is a need to improve the awareness of IBD and develop diagnostic and management recommendations relevant to the region. This evidence-based consensus focuses on the definition, epidemiology and management of ulcerative colitis (UC) in Asia. A multi-disciplinary group developed the consensus statements, reviewed the relevant literature, and voted on them anonymously using the Delphi method. The finalized statements were reviewed to determine the level of consensus, evidence quality and strength of recommendation. Infectious colitis must be excluded prior to diagnosing UC. Typical histology and macroscopic extent of the disease seen in the West is found in the Asia-Pacific region. Ulcerative colitis is increasing in many parts of Asia with gender distribution and age of diagnosis similar to the West. Extra-intestinal manifestations including primary sclerosing cholangitis are rarer than in the West. Clinical stratification of disease severity guides management. In Japan, leukocytapheresis is a treatment option. Access to biologic agents remains limited due to high cost and concern over opportunistic infections. The high endemic rates of hepatitis B virus infection require stringent screening before initiating immune-suppressive agents. Vaccination and prophylactic therapies should be initiated on a case-by-case basis and in accordance with local practice. Colorectal cancer complicates chronic colitis. A recent increase in UC is reported in the Asia-Pacific region. These consensus statements aim to improve the recognition of UC and assist clinicians in its management with particular relevance to the region. © 2010 Journal of Gastroenterology and Hepatology Foundation and Blackwell Publishing Asia Pty Ltd. |
| ISSN | 0815-9319 2011 Impact Factor: 2.865 2011 SCImago Journal Rankings: 0.208 |
| DOI | http://dx.doi.org/10.1111/j.1440-1746.2010.06241.x |
| ISI Accession Number ID | WOS:000274939900005 |
| References | References in Scopus |
| dc.contributor.author | Ooi, CJ |
|---|---|
| dc.contributor.author | Fock, KM |
| dc.contributor.author | Makharia, GK |
| dc.contributor.author | Goh, KL |
| dc.contributor.author | Ling, KL |
| dc.contributor.author | Hilmi, I |
| dc.contributor.author | Lim, WC |
| dc.contributor.author | Kelvin, T |
| dc.contributor.author | Gibson, PR |
| dc.contributor.author | Gearry, RB |
| dc.contributor.author | Ouyang, Q |
| dc.contributor.author | Sollano, J |
| dc.contributor.author | Manatsathit, S |
| dc.contributor.author | Rerknimitr, R |
| dc.contributor.author | Wei, SC |
| dc.contributor.author | Leung, WK |
| dc.contributor.author | De Silva, HJ |
| dc.contributor.author | Leong, RWL |
| dc.date.accessioned | 2011-04-04T07:57:24Z |
| dc.date.available | 2011-04-04T07:57:24Z |
| dc.date.issued | 2010 |
| dc.description.abstract | Inflammatory bowel disease (IBD) is increasing in many parts of the Asia-Pacific region. There is a need to improve the awareness of IBD and develop diagnostic and management recommendations relevant to the region. This evidence-based consensus focuses on the definition, epidemiology and management of ulcerative colitis (UC) in Asia. A multi-disciplinary group developed the consensus statements, reviewed the relevant literature, and voted on them anonymously using the Delphi method. The finalized statements were reviewed to determine the level of consensus, evidence quality and strength of recommendation. Infectious colitis must be excluded prior to diagnosing UC. Typical histology and macroscopic extent of the disease seen in the West is found in the Asia-Pacific region. Ulcerative colitis is increasing in many parts of Asia with gender distribution and age of diagnosis similar to the West. Extra-intestinal manifestations including primary sclerosing cholangitis are rarer than in the West. Clinical stratification of disease severity guides management. In Japan, leukocytapheresis is a treatment option. Access to biologic agents remains limited due to high cost and concern over opportunistic infections. The high endemic rates of hepatitis B virus infection require stringent screening before initiating immune-suppressive agents. Vaccination and prophylactic therapies should be initiated on a case-by-case basis and in accordance with local practice. Colorectal cancer complicates chronic colitis. A recent increase in UC is reported in the Asia-Pacific region. These consensus statements aim to improve the recognition of UC and assist clinicians in its management with particular relevance to the region. © 2010 Journal of Gastroenterology and Hepatology Foundation and Blackwell Publishing Asia Pty Ltd. |
| dc.description.nature | link_to_OA_fulltext |
| dc.identifier.citation | Journal Of Gastroenterology And Hepatology, 2010, v. 25 n. 3, p. 453-468 [How to Cite?] DOI: http://dx.doi.org/10.1111/j.1440-1746.2010.06241.x |
| dc.identifier.citeulike | 6841344 |
| dc.identifier.doi | http://dx.doi.org/10.1111/j.1440-1746.2010.06241.x |
| dc.identifier.eissn | 1440-1746 |
| dc.identifier.epage | 468 |
| dc.identifier.hkuros | 203859 |
| dc.identifier.isi | WOS:000274939900005 |
| dc.identifier.issn | 0815-9319 2011 Impact Factor: 2.865 2011 SCImago Journal Rankings: 0.208 |
| dc.identifier.issue | 3 |
| dc.identifier.pmid | 20370724 |
| dc.identifier.scopus | eid_2-s2.0-77649226304 |
| dc.identifier.spage | 453 |
| dc.identifier.uri | http://hdl.handle.net/10722/132848 |
| dc.identifier.volume | 25 |
| dc.language | eng |
| dc.publisher | Wiley-Blackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/JGH |
| dc.publisher.place | Australia |
| dc.relation.ispartof | Journal of Gastroenterology and Hepatology |
| dc.relation.references | References in Scopus |
| dc.subject.mesh | Colitis, Ulcerative - complications - diagnosis - drug therapy - epidemiology - therapy |
| dc.subject.mesh | Colorectal Neoplasms - etiology |
| dc.subject.mesh | Congresses as Topic |
| dc.subject.mesh | Humans |
| dc.subject.mesh | Immunosuppressive Agents - therapeutic use |
| dc.subject.mesh | Leukapheresis - methods |
| dc.subject.mesh | Practice Guidelines as Topic |
| dc.subject.mesh | Prevalence |
| dc.subject.mesh | Severity of Illness Index |
| dc.subject.mesh | Singapore - epidemiology |
| dc.subject | Chemicals And Cas Registry Numbers |
| dc.title | The Asia-Pacific consensus on ulcerative colitis |
| dc.type | Article |
Author Affiliations
- Singapore General Hospital
- University of Santo Tomas, Manila
- National Taiwan University
- Monash University
- Chulalongkorn University
- University of Malaya
- University of Otago
- All India Institute of Medical Sciences
- University of Kelaniya
- Changi General Hospital
- Tan Tock Seng Hospital
- Sichuan University
- Mahidol University
- Chinese University of Hong Kong
- University of New South Wales

