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Article: Five-year stability of ICD-10 diagnoses among Chinese patients presented with first-episode psychosis in Hong Kong

TitleFive-year stability of ICD-10 diagnoses among Chinese patients presented with first-episode psychosis in Hong Kong
Authors
KeywordsDiagnostic shift
Diagnostic stability
First-episode psychosis
Schizophrenia
Issue Date2009
PublisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/schres
Citation
Schizophrenia Research, 2009, v. 115 n. 2-3, p. 351-357 How to Cite?
AbstractBackground: Diagnostic stability is one measure of predictive validity for psychiatric syndromes. It is an under-studied area in functional psychosis despite its clinical and research implications. We aimed at evaluating the stability of ICD-10 diagnoses in a sample of young people with first-episode psychosis. Method: One hundred and sixty-six Hong Kong Chinese enrolled in a regional first-episode psychosis treatment program were studied. Subjects' baseline and final 5-year consensus diagnoses were established via systematic medical records' review to determine diagnostic stability and to identify predictors of diagnostic shift towards schizophrenia spectrum. Results: The overall diagnostic consistency was 80.7%. Bipolar affective disorder and schizophrenia were the most stable diagnostic categories over 5 years with prospective consistency of 100% and 95.8% respectively. The least stable baseline diagnoses were unspecified non-organic psychosis, acute and transient psychotic disorders and delusional disorder. Around one-fifth (19.3%) of subjects had diagnostic revision in 5 years. The predominant pattern of diagnostic shift was towards schizophrenia spectrum disorder. Family history of psychosis and longer duration of untreated psychosis were associated with diagnostic transition towards schizophrenia spectrum. Conclusions: Schizophrenia and bipolar affective disorder were diagnostically stable and could be reliably classified at intake in a Chinese first-episode psychosis sample using the ICD-10 criteria. Diagnostic instability in the least prevalent categories of functional psychosis highlights the limitations of current taxonomies and calls for ongoing revision of diagnostic criteria. In the absence of biological marker, longitudinal validation across consecutive episodes is necessary for accurate diagnostic ascertainment. © 2009 Elsevier B.V. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/132601
ISSN
2015 Impact Factor: 4.453
2015 SCImago Journal Rankings: 2.304
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorChang, WCen_HK
dc.contributor.authorPang, SLKen_HK
dc.contributor.authorChung, DWSen_HK
dc.contributor.authorChan, SSMen_HK
dc.date.accessioned2011-03-28T09:26:48Z-
dc.date.available2011-03-28T09:26:48Z-
dc.date.issued2009en_HK
dc.identifier.citationSchizophrenia Research, 2009, v. 115 n. 2-3, p. 351-357en_HK
dc.identifier.issn0920-9964en_HK
dc.identifier.urihttp://hdl.handle.net/10722/132601-
dc.description.abstractBackground: Diagnostic stability is one measure of predictive validity for psychiatric syndromes. It is an under-studied area in functional psychosis despite its clinical and research implications. We aimed at evaluating the stability of ICD-10 diagnoses in a sample of young people with first-episode psychosis. Method: One hundred and sixty-six Hong Kong Chinese enrolled in a regional first-episode psychosis treatment program were studied. Subjects' baseline and final 5-year consensus diagnoses were established via systematic medical records' review to determine diagnostic stability and to identify predictors of diagnostic shift towards schizophrenia spectrum. Results: The overall diagnostic consistency was 80.7%. Bipolar affective disorder and schizophrenia were the most stable diagnostic categories over 5 years with prospective consistency of 100% and 95.8% respectively. The least stable baseline diagnoses were unspecified non-organic psychosis, acute and transient psychotic disorders and delusional disorder. Around one-fifth (19.3%) of subjects had diagnostic revision in 5 years. The predominant pattern of diagnostic shift was towards schizophrenia spectrum disorder. Family history of psychosis and longer duration of untreated psychosis were associated with diagnostic transition towards schizophrenia spectrum. Conclusions: Schizophrenia and bipolar affective disorder were diagnostically stable and could be reliably classified at intake in a Chinese first-episode psychosis sample using the ICD-10 criteria. Diagnostic instability in the least prevalent categories of functional psychosis highlights the limitations of current taxonomies and calls for ongoing revision of diagnostic criteria. In the absence of biological marker, longitudinal validation across consecutive episodes is necessary for accurate diagnostic ascertainment. © 2009 Elsevier B.V. All rights reserved.en_HK
dc.languageengen_US
dc.publisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/schresen_HK
dc.relation.ispartofSchizophrenia Researchen_HK
dc.subjectDiagnostic shiften_HK
dc.subjectDiagnostic stabilityen_HK
dc.subjectFirst-episode psychosisen_HK
dc.subjectSchizophreniaen_HK
dc.titleFive-year stability of ICD-10 diagnoses among Chinese patients presented with first-episode psychosis in Hong Kongen_HK
dc.typeArticleen_HK
dc.identifier.emailChang, WC: changwc@hku.hken_HK
dc.identifier.authorityChang, WC=rp01465en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/j.schres.2009.09.037en_HK
dc.identifier.pmid19840896-
dc.identifier.scopuseid_2-s2.0-71649113058en_HK
dc.identifier.hkuros222418-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-71649113058&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume115en_HK
dc.identifier.issue2-3en_HK
dc.identifier.spage351en_HK
dc.identifier.epage357en_HK
dc.identifier.eissn1573-2509-
dc.identifier.isiWOS:000272423500035-
dc.publisher.placeNetherlandsen_HK
dc.identifier.scopusauthoridChang, WC=26643706700en_HK
dc.identifier.scopusauthoridPang, SLK=35093068300en_HK
dc.identifier.scopusauthoridChung, DWS=7401719312en_HK
dc.identifier.scopusauthoridChan, SSM=13409371900en_HK
dc.identifier.citeulike6005146-

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