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Article: Risk and management of upper gastrointestinal bleeding associated with prolonged dual-antiplatelet therapy after percutaneous coronary intervention

TitleRisk and management of upper gastrointestinal bleeding associated with prolonged dual-antiplatelet therapy after percutaneous coronary intervention
Authors
KeywordsChemicals And Cas Registry Numbers
Issue Date2009
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/carrev
Citation
Cardiovascular Revascularization Medicine, 2009, v. 10 n. 1, p. 36-44 How to Cite?
AbstractProlonged dual-antiplatelet therapy with aspirin and clopidogrel is mandatory after drug-eluting stent implantation because of the potential increased risk of late stent thrombosis. The concern regarding prolonged antiplatelet therapy is the increased risk of bleeding. Gastrointestinal bleeding is the most common site of bleeding and presents a serious threat to patients due to the competing risks of gastrointestinal hemorrhage and stent thrombosis. Currently, there are no guidelines and little evidence on how best to manage these patients who are at high risk of morbidity and mortality from both the bleeding itself and the consequences of achieving optimum hemostasis by interruption of antiplatelet therapy. Managing gastrointestinal bleeding in a patient who has undergone recent percutaneous coronary intervention requires balancing the risk of stent thrombosis against further catastrophic bleeding. Close combined management between gastroenterologist and cardiologist is advocated to optimize patient outcomes. © 2009 Elsevier Inc. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/132486
ISSN
2015 SCImago Journal Rankings: 0.583
References

 

DC FieldValueLanguage
dc.contributor.authorTan, VPen_HK
dc.contributor.authorYan, BPen_HK
dc.contributor.authorKiernan, TJen_HK
dc.contributor.authorAjani, AEen_HK
dc.date.accessioned2011-03-28T09:25:17Z-
dc.date.available2011-03-28T09:25:17Z-
dc.date.issued2009en_HK
dc.identifier.citationCardiovascular Revascularization Medicine, 2009, v. 10 n. 1, p. 36-44en_HK
dc.identifier.issn1553-8389en_HK
dc.identifier.urihttp://hdl.handle.net/10722/132486-
dc.description.abstractProlonged dual-antiplatelet therapy with aspirin and clopidogrel is mandatory after drug-eluting stent implantation because of the potential increased risk of late stent thrombosis. The concern regarding prolonged antiplatelet therapy is the increased risk of bleeding. Gastrointestinal bleeding is the most common site of bleeding and presents a serious threat to patients due to the competing risks of gastrointestinal hemorrhage and stent thrombosis. Currently, there are no guidelines and little evidence on how best to manage these patients who are at high risk of morbidity and mortality from both the bleeding itself and the consequences of achieving optimum hemostasis by interruption of antiplatelet therapy. Managing gastrointestinal bleeding in a patient who has undergone recent percutaneous coronary intervention requires balancing the risk of stent thrombosis against further catastrophic bleeding. Close combined management between gastroenterologist and cardiologist is advocated to optimize patient outcomes. © 2009 Elsevier Inc. All rights reserved.en_HK
dc.languageengen_US
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/carreven_HK
dc.relation.ispartofCardiovascular Revascularization Medicineen_HK
dc.subjectChemicals And Cas Registry Numbersen_US
dc.titleRisk and management of upper gastrointestinal bleeding associated with prolonged dual-antiplatelet therapy after percutaneous coronary interventionen_HK
dc.typeArticleen_HK
dc.identifier.emailTan, Victoria Ping Yi:vpytan@hku.hken_US
dc.identifier.authorityTan, Victoria Ping Yi=rp01458en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/j.carrev.2008.11.001en_HK
dc.identifier.pmid19159853-
dc.identifier.scopuseid_2-s2.0-58249130322en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-58249130322&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume10en_HK
dc.identifier.issue1en_HK
dc.identifier.spage36en_HK
dc.identifier.epage44en_HK
dc.publisher.placeUnited Statesen_HK

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