File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Embryonic XMab21l2 expression is required for gastrulation and subsequent neural development

TitleEmbryonic XMab21l2 expression is required for gastrulation and subsequent neural development
Authors
KeywordsEmbryonic expression
Gastrulation
RNAi
XMab21l2
Issue Date2001
PublisherAcademic Press. The Journal's web site is located at http://www.elsevier.com/wps/find/journaldescription.cws_home/622790/description
Citation
Biochemical And Biophysical Research Communications, 2001, v. 280 n. 5, p. 1378-1384 How to Cite?
AbstractCell fate determining gene mab-21 regulates the proper establishment of neural cell fate and sensory organ identity in nematode. Mammalian homologs of mab-21 have also been implicated to play critical roles in mid-, hindbrain and craniofacial differentiation. We report here the isolation of a mab-21 homolog, XMab21l2, from Xenopus. We showed that its expression in Xenopus was initiated at gastrulation and prominent signal was detected in neurulating embryos at the neural tube, the optic tissue, the developing midbrain, and the pharyngeal pouches. We demonstrated by RNA interference (RNAi), together with other antisense approaches, that XMab21l2 expression is required for the completion of gastrulation and subsequent neural development. © 2001 Academic Press.
Persistent Identifierhttp://hdl.handle.net/10722/132365
ISSN
2015 Impact Factor: 2.371
2015 SCImago Journal Rankings: 1.152
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLau, GTCen_HK
dc.contributor.authorWong, OGWen_HK
dc.contributor.authorChan, PMYen_HK
dc.contributor.authorKok, KHen_HK
dc.contributor.authorWong, RLYen_HK
dc.contributor.authorChin, KTen_HK
dc.contributor.authorLin, MCMen_HK
dc.contributor.authorKung, HFen_HK
dc.contributor.authorChow, KLen_HK
dc.date.accessioned2011-03-28T09:23:37Z-
dc.date.available2011-03-28T09:23:37Z-
dc.date.issued2001en_HK
dc.identifier.citationBiochemical And Biophysical Research Communications, 2001, v. 280 n. 5, p. 1378-1384en_HK
dc.identifier.issn0006-291Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/132365-
dc.description.abstractCell fate determining gene mab-21 regulates the proper establishment of neural cell fate and sensory organ identity in nematode. Mammalian homologs of mab-21 have also been implicated to play critical roles in mid-, hindbrain and craniofacial differentiation. We report here the isolation of a mab-21 homolog, XMab21l2, from Xenopus. We showed that its expression in Xenopus was initiated at gastrulation and prominent signal was detected in neurulating embryos at the neural tube, the optic tissue, the developing midbrain, and the pharyngeal pouches. We demonstrated by RNA interference (RNAi), together with other antisense approaches, that XMab21l2 expression is required for the completion of gastrulation and subsequent neural development. © 2001 Academic Press.en_HK
dc.languageengen_US
dc.publisherAcademic Press. The Journal's web site is located at http://www.elsevier.com/wps/find/journaldescription.cws_home/622790/descriptionen_HK
dc.relation.ispartofBiochemical and Biophysical Research Communicationsen_HK
dc.subjectEmbryonic expressionen_HK
dc.subjectGastrulationen_HK
dc.subjectRNAien_HK
dc.subjectXMab21l2en_HK
dc.subject.meshAmino Acid Sequenceen_HK
dc.subject.meshAnimalsen_HK
dc.subject.meshDNA - chemistry - genetics - isolation & purificationen_HK
dc.subject.meshEmbryo, Nonmammalian - drug effects - metabolismen_HK
dc.subject.meshEmbryonic Developmenten_HK
dc.subject.meshGastrula - metabolismen_HK
dc.subject.meshGene Expression Regulation, Developmental - drug effectsen_HK
dc.subject.meshHomeodomain Proteins - geneticsen_HK
dc.subject.meshMolecular Sequence Dataen_HK
dc.subject.meshNervous System - embryology - metabolismen_HK
dc.subject.meshPhenotypeen_HK
dc.subject.meshRNA - genetics - metabolismen_HK
dc.subject.meshRNA, Antisense - pharmacologyen_HK
dc.subject.meshRNA, Double-Stranded - pharmacologyen_HK
dc.subject.meshRNA, Messenger - pharmacologyen_HK
dc.subject.meshSequence Alignmenten_HK
dc.subject.meshSequence Analysis, DNAen_HK
dc.subject.meshSequence Homology, Amino Aciden_HK
dc.subject.meshXenopus - embryology - geneticsen_HK
dc.titleEmbryonic XMab21l2 expression is required for gastrulation and subsequent neural developmenten_HK
dc.typeArticleen_HK
dc.identifier.emailKok, KH:khkok@hku.hken_HK
dc.identifier.emailLin, MCM:mcllin@hkucc.hku.hken_HK
dc.identifier.authorityKok, KH=rp01455en_HK
dc.identifier.authorityLin, MCM=rp00746en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1006/bbrc.2001.4290en_HK
dc.identifier.pmid11162683-
dc.identifier.scopuseid_2-s2.0-0034816522en_HK
dc.identifier.hkuros60696-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0034816522&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume280en_HK
dc.identifier.issue5en_HK
dc.identifier.spage1378en_HK
dc.identifier.epage1384en_HK
dc.identifier.isiWOS:000167128500028-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridLau, GTC=36958025200en_HK
dc.identifier.scopusauthoridWong, OGW=7004813981en_HK
dc.identifier.scopusauthoridChan, PMY=15735672000en_HK
dc.identifier.scopusauthoridKok, KH=7006862631en_HK
dc.identifier.scopusauthoridWong, RLY=15736375300en_HK
dc.identifier.scopusauthoridChin, KT=7202995491en_HK
dc.identifier.scopusauthoridLin, MCM=7404816359en_HK
dc.identifier.scopusauthoridKung, HF=7402514190en_HK
dc.identifier.scopusauthoridChow, KL=7202180729en_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats