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Conference Paper: The use of a noninvasive and nondestructive method, microcomputed tomography, to evaluate the anti-osteoporotic activity of erxian decoction, a Chinese medicinal formula, in a rat model of menopausal osteoporosis

TitleThe use of a noninvasive and nondestructive method, microcomputed tomography, to evaluate the anti-osteoporotic activity of erxian decoction, a Chinese medicinal formula, in a rat model of menopausal osteoporosis
Authors
KeywordsChinese medicine
Erxian decoction
Estradiol and menopause
Microcomputed tomography
Osteoporosis
Issue Date2009
Citation
The 2nd International Conference on Biomedical Engineering and Informatics (BMEI 2009), Tianjin, China, 17-19 October 2009. In Conference Proceedings, 2009, v. 1 p. 47-49, article no. 5304821 How to Cite?
AbstractAim of the study: The anti-osteoporotic activity of Erxian Decoction, a Chinese medicinal formula, in a rat model of menopausal osteoporosis was evaluated by microcomputed tomography (microCT). Materials and methods: Menopause causes a decline in both endocrine function and bone mineral density in human. In this study, 20-month-old female Sprague-Dawley-rats (SD-rats) with a low serum estradiol level and bone mineral density were employed. The anti-osteoporotic activity of EXD was assessed by the determination of trabecular material bone mineral density at the L2 mid-vertebral body after treatment. Serum estrogen levels were also determined to assess the effect of EXD on the endocrine status. Results: Results revealed a significant elevation in serum estradiol level and trabecular bone mineral density at the L2 mid-vertebral body in the EXD-treated menopausal rat model. Conclusions: The results obtained from the present investigation revealed that the EXD had anti-osteoporotic activity as evidenced by an increase of serum estradiol level and bone mineral density. ©2009 IEEE.
Persistent Identifierhttp://hdl.handle.net/10722/130087
References

 

DC FieldValueLanguage
dc.contributor.authorSze, SCWen_HK
dc.contributor.authorTong, Yen_HK
dc.contributor.authorZhang, YBen_HK
dc.contributor.authorZhong, LLDen_HK
dc.contributor.authorLau, ASLen_HK
dc.contributor.authorYow, CMNen_HK
dc.contributor.authorLai, YMen_HK
dc.contributor.authorNg, TBen_HK
dc.date.accessioned2010-12-23T08:46:45Z-
dc.date.available2010-12-23T08:46:45Z-
dc.date.issued2009en_HK
dc.identifier.citationThe 2nd International Conference on Biomedical Engineering and Informatics (BMEI 2009), Tianjin, China, 17-19 October 2009. In Conference Proceedings, 2009, v. 1 p. 47-49, article no. 5304821en_HK
dc.identifier.urihttp://hdl.handle.net/10722/130087-
dc.description.abstractAim of the study: The anti-osteoporotic activity of Erxian Decoction, a Chinese medicinal formula, in a rat model of menopausal osteoporosis was evaluated by microcomputed tomography (microCT). Materials and methods: Menopause causes a decline in both endocrine function and bone mineral density in human. In this study, 20-month-old female Sprague-Dawley-rats (SD-rats) with a low serum estradiol level and bone mineral density were employed. The anti-osteoporotic activity of EXD was assessed by the determination of trabecular material bone mineral density at the L2 mid-vertebral body after treatment. Serum estrogen levels were also determined to assess the effect of EXD on the endocrine status. Results: Results revealed a significant elevation in serum estradiol level and trabecular bone mineral density at the L2 mid-vertebral body in the EXD-treated menopausal rat model. Conclusions: The results obtained from the present investigation revealed that the EXD had anti-osteoporotic activity as evidenced by an increase of serum estradiol level and bone mineral density. ©2009 IEEE.en_HK
dc.languageengen_US
dc.relation.ispartofProceedings of the 2nd International Conference on Biomedical Engineering and Informatics, BMEI 2009en_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subjectChinese medicineen_HK
dc.subjectErxian decoctionen_HK
dc.subjectEstradiol and menopauseen_HK
dc.subjectMicrocomputed tomographyen_HK
dc.subjectOsteoporosisen_HK
dc.titleThe use of a noninvasive and nondestructive method, microcomputed tomography, to evaluate the anti-osteoporotic activity of erxian decoction, a Chinese medicinal formula, in a rat model of menopausal osteoporosisen_HK
dc.typeConference_Paperen_HK
dc.identifier.emailSze, SCW: stephens@hku.hken_HK
dc.identifier.emailTong, Y: tongyao@hku.hken_HK
dc.identifier.emailZhang, YB: ybzhang@hku.hken_HK
dc.identifier.authoritySze, SCW=rp00514en_HK
dc.identifier.authorityTong, Y=rp00509en_HK
dc.identifier.authorityZhang, YB=rp01410en_HK
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1109/BMEI.2009.5304821en_HK
dc.identifier.scopuseid_2-s2.0-74049126578en_HK
dc.identifier.hkuros177276en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-74049126578&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume1en_US
dc.identifier.spage47en_US
dc.identifier.epage49, article number 5304821en_US
dc.description.otherProceedings of the 2009 2nd International Conference On Biomedical Engineering And Informatics (BMEI 2009), Tianjin, China, 17-19 October 2009, v. 1 p. 47-49, article number 5304821-
dc.identifier.scopusauthoridSze, SCW=23482617000en_HK
dc.identifier.scopusauthoridTong, Y=9045384000en_HK
dc.identifier.scopusauthoridZhang, YB=23483121900en_HK
dc.identifier.scopusauthoridZhong, LLD=55032067800en_HK
dc.identifier.scopusauthoridLau, ASL=26030476700en_HK
dc.identifier.scopusauthoridYow, CMN=6602535418en_HK
dc.identifier.scopusauthoridLai, YM=7401512093en_HK
dc.identifier.scopusauthoridNg, TB=35311803300en_HK
dc.customcontrol.immutablesml 161206 - amended-

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