Article: Antioxidant properties and principal phenolic phytochemicals of Indian medicinal plants from Asclepiadoideae and Periplocoideae

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TitleAntioxidant properties and principal phenolic phytochemicals of Indian medicinal plants from Asclepiadoideae and Periplocoideae
AuthorsSurveswaran, S1
Cai, YZ1
Xing, J2
Corke, H1
Sun, M1
KeywordsAntioxidant activity
Asclepiadaceae
Chlorogenic acid
Flavonoids
Phenolic compounds
Issue Date2010
PublisherTaylor & Francis Ltd. The Journal's web site is located at http://www.tandf.co.uk/journals/titles/14786419.asp
CitationNatural Product Research, 2010, v. 24 n. 3, p. 206-221 [How to Cite?]
DOI: http://dx.doi.org/10.1080/14786410802228827
AbstractThe subfamily Asclepiadoideae (Apocynaceae) and the closely-related Periplocoideae are sources of many indigenous Indian medicinal plants. We surveyed antioxidant properties and total phenolic and flavonoid contents of 15 samples, representing 12 Indian medicinal plant species from these subfamilies. Total antioxidant assay was performed using the 2,2-azinobis-3- ethylbenzothiazoline-6-sulfonic acid and ferric-reducing antioxidant power methods. Total phenolic and flavonoid contents were measured using colourimetric methods. Principal phenolic compounds were detected by liquid chromatography-mass spectrometry (LC-MS). The highest antioxidant capacity and high levels of total phenolics and flavonoids were found in the leaves of Decalepis hamiltonii. The stems of Sarcostemma brevistigma exhibited the highest xanthine oxidase (XO) inhibitory activity. The roots of Hemidesmus indicus showed the highest OH - radical scavenging activity. In general, Periplocoideae members exhibited higher antioxidant activity than Asclepiadoideae members. The highly significant and positive correlations (R> 0.914) between total antioxidant capacity parameters and total phenolic content indicated that the phenolic compounds contributed significantly to the antioxidant activity of the tested plant samples. The principal phenolic phytochemicals from these plants were identified by LC-MS, including flavonoids, phenolic acids and phenolic terpenoids. Chlorogenic acid and rutin were detected in almost all of the plant samples. The LC-MS analysis provided full fingerprints of the principal phenolic compounds in the medicinal plants from these two subfamilies, which are useful for their authentication and quality evaluation. © 2010 Taylor & Francis.
ISSN1478-6419
2011 Impact Factor: 1.009
2011 SCImago Journal Rankings: 0.053
DOIhttp://dx.doi.org/10.1080/14786410802228827
ISI Accession Number IDWOS:000274535600002
Funding AgencyGrant Number
University of Hong Kong (Seed Funding for Basic Research)
Funding Information:

This research was supported by grants from the University of Hong Kong (Seed Funding for Basic Research). We thank Wuyang Huang for assistance with LC-MS analysis and Mayur Kamble for help in obtaining some plant specimens.

ReferencesReferences in Scopus
DC Field
Value
dc.contributor.authorSurveswaran, S
dc.contributor.authorCai, YZ
dc.contributor.authorXing, J
dc.contributor.authorCorke, H
dc.contributor.authorSun, M
dc.date.accessioned2010-12-23T08:45:42Z
dc.date.available2010-12-23T08:45:42Z
dc.date.issued2010
dc.description.abstractThe subfamily Asclepiadoideae (Apocynaceae) and the closely-related Periplocoideae are sources of many indigenous Indian medicinal plants. We surveyed antioxidant properties and total phenolic and flavonoid contents of 15 samples, representing 12 Indian medicinal plant species from these subfamilies. Total antioxidant assay was performed using the 2,2-azinobis-3- ethylbenzothiazoline-6-sulfonic acid and ferric-reducing antioxidant power methods. Total phenolic and flavonoid contents were measured using colourimetric methods. Principal phenolic compounds were detected by liquid chromatography-mass spectrometry (LC-MS). The highest antioxidant capacity and high levels of total phenolics and flavonoids were found in the leaves of Decalepis hamiltonii. The stems of Sarcostemma brevistigma exhibited the highest xanthine oxidase (XO) inhibitory activity. The roots of Hemidesmus indicus showed the highest OH - radical scavenging activity. In general, Periplocoideae members exhibited higher antioxidant activity than Asclepiadoideae members. The highly significant and positive correlations (R> 0.914) between total antioxidant capacity parameters and total phenolic content indicated that the phenolic compounds contributed significantly to the antioxidant activity of the tested plant samples. The principal phenolic phytochemicals from these plants were identified by LC-MS, including flavonoids, phenolic acids and phenolic terpenoids. Chlorogenic acid and rutin were detected in almost all of the plant samples. The LC-MS analysis provided full fingerprints of the principal phenolic compounds in the medicinal plants from these two subfamilies, which are useful for their authentication and quality evaluation. © 2010 Taylor & Francis.
dc.description.natureLink_to_subscribed_fulltext
dc.identifier.citationNatural Product Research, 2010, v. 24 n. 3, p. 206-221 [How to Cite?]
DOI: http://dx.doi.org/10.1080/14786410802228827
dc.identifier.doihttp://dx.doi.org/10.1080/14786410802228827
dc.identifier.epage221
dc.identifier.hkuros178501
dc.identifier.isiWOS:000274535600002
Funding AgencyGrant Number
University of Hong Kong (Seed Funding for Basic Research)
Funding Information:

This research was supported by grants from the University of Hong Kong (Seed Funding for Basic Research). We thank Wuyang Huang for assistance with LC-MS analysis and Mayur Kamble for help in obtaining some plant specimens.

dc.identifier.issn1478-6419
2011 Impact Factor: 1.009
2011 SCImago Journal Rankings: 0.053
dc.identifier.issue3
dc.identifier.openurl
dc.identifier.pmid20140800
dc.identifier.scopuseid_2-s2.0-77049119550
dc.identifier.spage206
dc.identifier.urihttp://hdl.handle.net/10722/130029
dc.identifier.volume24
dc.languageeng
dc.publisherTaylor & Francis Ltd. The Journal's web site is located at http://www.tandf.co.uk/journals/titles/14786419.asp
dc.publisher.placeUnited Kingdom
dc.relation.ispartofNatural Product Research
dc.relation.referencesReferences in Scopus
dc.subject.meshAntioxidants - chemistry - pharmacology
dc.subject.meshApocynaceae - chemistry
dc.subject.meshFlavonoids - chemistry - pharmacology
dc.subject.meshPhenols - chemistry - pharmacology
dc.subject.meshPlants, Medicinal - chemistry
dc.subjectAntioxidant activity
dc.subjectAsclepiadaceae
dc.subjectChlorogenic acid
dc.subjectFlavonoids
dc.subjectPhenolic compounds
dc.titleAntioxidant properties and principal phenolic phytochemicals of Indian medicinal plants from Asclepiadoideae and Periplocoideae
dc.typeArticle
Author Affiliations
  1. The University of Hong Kong
  2. Republic Polytechnic