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Article: Antioxidant properties and principal phenolic phytochemicals of Indian medicinal plants from Asclepiadoideae and Periplocoideae

TitleAntioxidant properties and principal phenolic phytochemicals of Indian medicinal plants from Asclepiadoideae and Periplocoideae
Authors
KeywordsAntioxidant activity
Asclepiadaceae
Chlorogenic acid
Flavonoids
Phenolic compounds
Issue Date2010
PublisherTaylor & Francis Ltd. The Journal's web site is located at http://www.tandf.co.uk/journals/titles/14786419.asp
Citation
Natural Product Research, 2010, v. 24 n. 3, p. 206-221 How to Cite?
Abstract
The subfamily Asclepiadoideae (Apocynaceae) and the closely-related Periplocoideae are sources of many indigenous Indian medicinal plants. We surveyed antioxidant properties and total phenolic and flavonoid contents of 15 samples, representing 12 Indian medicinal plant species from these subfamilies. Total antioxidant assay was performed using the 2,2-azinobis-3- ethylbenzothiazoline-6-sulfonic acid and ferric-reducing antioxidant power methods. Total phenolic and flavonoid contents were measured using colourimetric methods. Principal phenolic compounds were detected by liquid chromatography-mass spectrometry (LC-MS). The highest antioxidant capacity and high levels of total phenolics and flavonoids were found in the leaves of Decalepis hamiltonii. The stems of Sarcostemma brevistigma exhibited the highest xanthine oxidase (XO) inhibitory activity. The roots of Hemidesmus indicus showed the highest OH - radical scavenging activity. In general, Periplocoideae members exhibited higher antioxidant activity than Asclepiadoideae members. The highly significant and positive correlations (R> 0.914) between total antioxidant capacity parameters and total phenolic content indicated that the phenolic compounds contributed significantly to the antioxidant activity of the tested plant samples. The principal phenolic phytochemicals from these plants were identified by LC-MS, including flavonoids, phenolic acids and phenolic terpenoids. Chlorogenic acid and rutin were detected in almost all of the plant samples. The LC-MS analysis provided full fingerprints of the principal phenolic compounds in the medicinal plants from these two subfamilies, which are useful for their authentication and quality evaluation. © 2010 Taylor & Francis.
Persistent Identifierhttp://hdl.handle.net/10722/130029
ISSN
2013 Impact Factor: 1.225
ISI Accession Number ID
Funding AgencyGrant Number
University of Hong Kong (Seed Funding for Basic Research)
Funding Information:

This research was supported by grants from the University of Hong Kong (Seed Funding for Basic Research). We thank Wuyang Huang for assistance with LC-MS analysis and Mayur Kamble for help in obtaining some plant specimens.

References

 

DC FieldValueLanguage
dc.contributor.authorSurveswaran, Sen_HK
dc.contributor.authorCai, YZen_HK
dc.contributor.authorXing, Jen_HK
dc.contributor.authorCorke, Hen_HK
dc.contributor.authorSun, Men_HK
dc.date.accessioned2010-12-23T08:45:42Z-
dc.date.available2010-12-23T08:45:42Z-
dc.date.issued2010en_HK
dc.identifier.citationNatural Product Research, 2010, v. 24 n. 3, p. 206-221en_HK
dc.identifier.issn1478-6419en_HK
dc.identifier.urihttp://hdl.handle.net/10722/130029-
dc.description.abstractThe subfamily Asclepiadoideae (Apocynaceae) and the closely-related Periplocoideae are sources of many indigenous Indian medicinal plants. We surveyed antioxidant properties and total phenolic and flavonoid contents of 15 samples, representing 12 Indian medicinal plant species from these subfamilies. Total antioxidant assay was performed using the 2,2-azinobis-3- ethylbenzothiazoline-6-sulfonic acid and ferric-reducing antioxidant power methods. Total phenolic and flavonoid contents were measured using colourimetric methods. Principal phenolic compounds were detected by liquid chromatography-mass spectrometry (LC-MS). The highest antioxidant capacity and high levels of total phenolics and flavonoids were found in the leaves of Decalepis hamiltonii. The stems of Sarcostemma brevistigma exhibited the highest xanthine oxidase (XO) inhibitory activity. The roots of Hemidesmus indicus showed the highest OH - radical scavenging activity. In general, Periplocoideae members exhibited higher antioxidant activity than Asclepiadoideae members. The highly significant and positive correlations (R> 0.914) between total antioxidant capacity parameters and total phenolic content indicated that the phenolic compounds contributed significantly to the antioxidant activity of the tested plant samples. The principal phenolic phytochemicals from these plants were identified by LC-MS, including flavonoids, phenolic acids and phenolic terpenoids. Chlorogenic acid and rutin were detected in almost all of the plant samples. The LC-MS analysis provided full fingerprints of the principal phenolic compounds in the medicinal plants from these two subfamilies, which are useful for their authentication and quality evaluation. © 2010 Taylor & Francis.en_HK
dc.languageengen_US
dc.publisherTaylor & Francis Ltd. The Journal's web site is located at http://www.tandf.co.uk/journals/titles/14786419.aspen_HK
dc.relation.ispartofNatural Product Researchen_HK
dc.subjectAntioxidant activityen_HK
dc.subjectAsclepiadaceaeen_HK
dc.subjectChlorogenic aciden_HK
dc.subjectFlavonoidsen_HK
dc.subjectPhenolic compoundsen_HK
dc.subject.meshAntioxidants - chemistry - pharmacology-
dc.subject.meshApocynaceae - chemistry-
dc.subject.meshFlavonoids - chemistry - pharmacology-
dc.subject.meshPhenols - chemistry - pharmacology-
dc.subject.meshPlants, Medicinal - chemistry-
dc.titleAntioxidant properties and principal phenolic phytochemicals of Indian medicinal plants from Asclepiadoideae and Periplocoideaeen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1478-6419&volume=24&issue=3&spage=206&epage=221&date=2010&atitle=Antioxidant+properties+and+principal+phenolic+phytochemicals+of+Indian+medicinal+plants+from+Asclepiadoideae+and+Periplocoideae-
dc.identifier.emailSurveswaran, S: sid1@hkucc.hku.hken_HK
dc.identifier.emailCai, YZ: yzcai@hkucc.hku.hken_HK
dc.identifier.emailCorke, H: harold@hku.hken_HK
dc.identifier.emailSun, M: meisun@hkucc.hku.hken_HK
dc.identifier.authoritySurveswaran, S=rp00783en_HK
dc.identifier.authorityCai, YZ=rp00661en_HK
dc.identifier.authorityCorke, H=rp00688en_HK
dc.identifier.authoritySun, M=rp00779en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1080/14786410802228827en_HK
dc.identifier.pmid20140800en_HK
dc.identifier.scopuseid_2-s2.0-77049119550en_HK
dc.identifier.hkuros178501en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-77049119550&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume24en_HK
dc.identifier.issue3en_HK
dc.identifier.spage206en_HK
dc.identifier.epage221en_HK
dc.identifier.isiWOS:000274535600002-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridSurveswaran, S=15766021500en_HK
dc.identifier.scopusauthoridCai, YZ=8684149300en_HK
dc.identifier.scopusauthoridXing, J=37162498100en_HK
dc.identifier.scopusauthoridCorke, H=7007102942en_HK
dc.identifier.scopusauthoridSun, M=7403181447en_HK

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