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Conference Paper: Bone morphogenetic protein incorporated nanocomposite scaffolds and induction of osteogenic differentiation of mesenchymal stem cells

TitleBone morphogenetic protein incorporated nanocomposite scaffolds and induction of osteogenic differentiation of mesenchymal stem cells
Authors
Duan, BWang, MLi, ZLu, WW
Issue Date2010
PublisherTERMIS.
Citation
The Tissue Engineering and Regenerative Medicine Conference (TERMIS-EU 2010), Galway, Ireland, 13-17 June 2010. How to Cite?
AbstractINTRODUCTION: Due to its distinctive advantages, selective laser sintering (SLS), which is a mature rapid prototyping technology, is being investigated for constructing nanocomposite bone tissue engineering (BTE) scaffolds [1]. One of the effective strategies in BTE is to combine a TE scaffold with bioactive molecules for regulating the osteogenic differentiation of stem cells, stimulating tissue formation and accelerating healing. Engineering functional cell-scaffold complexes with desired scaffold architecture, hierarchical structure, and temporal and spatial delivery capability of bioactive molecules in a controlled manner is still a scientific and technological challenge [2]. In this study, 3D SLS sintered Ca-P/PHBV scaffolds were surface modified for incorporating recombinant bone morphogenetic protein-2 (rhBMP-2). The behaviour of human umbilical cord derived mesenchymal stem cells (hUC-MSCs) on the scaffolds was then investigated….
DescriptionPaper no. 459
Persistent Identifierhttp://hdl.handle.net/10722/129756

 

DC FieldValueLanguage
dc.contributor.authorDuan, Ben_US
dc.contributor.authorWang, Men_US
dc.contributor.authorLi, Zen_US
dc.contributor.authorLu, WWen_US
dc.date.accessioned2010-12-23T08:41:55Z-
dc.date.available2010-12-23T08:41:55Z-
dc.date.issued2010en_US
dc.identifier.citationThe Tissue Engineering and Regenerative Medicine Conference (TERMIS-EU 2010), Galway, Ireland, 13-17 June 2010.en_US
dc.identifier.urihttp://hdl.handle.net/10722/129756-
dc.descriptionPaper no. 459-
dc.description.abstractINTRODUCTION: Due to its distinctive advantages, selective laser sintering (SLS), which is a mature rapid prototyping technology, is being investigated for constructing nanocomposite bone tissue engineering (BTE) scaffolds [1]. One of the effective strategies in BTE is to combine a TE scaffold with bioactive molecules for regulating the osteogenic differentiation of stem cells, stimulating tissue formation and accelerating healing. Engineering functional cell-scaffold complexes with desired scaffold architecture, hierarchical structure, and temporal and spatial delivery capability of bioactive molecules in a controlled manner is still a scientific and technological challenge [2]. In this study, 3D SLS sintered Ca-P/PHBV scaffolds were surface modified for incorporating recombinant bone morphogenetic protein-2 (rhBMP-2). The behaviour of human umbilical cord derived mesenchymal stem cells (hUC-MSCs) on the scaffolds was then investigated….-
dc.languageengen_US
dc.publisherTERMIS.-
dc.relation.ispartofProceedings of TERMIS-EU 2010 Conferenceen_US
dc.titleBone morphogenetic protein incorporated nanocomposite scaffolds and induction of osteogenic differentiation of mesenchymal stem cellsen_US
dc.typeConference_Paperen_US
dc.identifier.emailWang, M: memwang@hku.hken_US
dc.identifier.emailLi, Z: lizy@hku.hken_US
dc.identifier.emailLu, WW: wwlu@hku.hken_US
dc.identifier.authorityWang, M=rp00185en_US
dc.identifier.authorityLu, WW=rp00411en_US
dc.description.naturelink_to_OA_fulltext-
dc.identifier.hkuros177896en_US
dc.description.otherThe Tissue Engineering and Regenerative Medicine Conference (TERMIS-EU 2010), Galway, Ireland, 13-17 June 2010. In Proceedings of TERMIS-EU, 2010-

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