Conference Paper: In vivo demonstration of enhancing gas-filled microbubble magnetic susceptibility with iron oxide nanoparticles

TitleIn vivo demonstration of enhancing gas-filled microbubble magnetic susceptibility with iron oxide nanoparticles
Authors
Issue Date2010
Citation
The ISMRM-ESMRMB Joint Annual Meeting 2010, Stockholm, Sweden, 1-7 May 2010. How to Cite?
AbstractGas-filled microbubbles have been shown as an MR susceptibility contrast agent; however, microbubble susceptibility effect is relatively weak when compared with other contrast agents. Studies have indicated that, by embedding magnetic nanoparticles, the magnetic susceptibility of the shell can be increased, thus enhancing the microbubble susceptibility effect. In this study, we further demonstrated the synergistic effect of gas core with iron oxide nanoparticles in achieving the overall microbubble susceptibility effect and characterized in vivo enhancements of microbubble susceptibility effects by entrapping iron oxide nanoparticles at 7 T, leading to the practical use of microbubbles as an intravascular MRI contrast agent.
DescriptionShort TE & Susceptibility MRI: No. 698
Persistent Identifierhttp://hdl.handle.net/10722/129690

 

DC FieldValueLanguage
dc.contributor.authorChow, AMKen_US
dc.contributor.authorChan, KWYen_US
dc.contributor.authorWu, EXen_US
dc.date.accessioned2010-12-23T08:41:02Z-
dc.date.available2010-12-23T08:41:02Z-
dc.date.issued2010en_US
dc.identifier.citationThe ISMRM-ESMRMB Joint Annual Meeting 2010, Stockholm, Sweden, 1-7 May 2010.en_US
dc.identifier.urihttp://hdl.handle.net/10722/129690-
dc.descriptionShort TE & Susceptibility MRI: No. 698-
dc.description.abstractGas-filled microbubbles have been shown as an MR susceptibility contrast agent; however, microbubble susceptibility effect is relatively weak when compared with other contrast agents. Studies have indicated that, by embedding magnetic nanoparticles, the magnetic susceptibility of the shell can be increased, thus enhancing the microbubble susceptibility effect. In this study, we further demonstrated the synergistic effect of gas core with iron oxide nanoparticles in achieving the overall microbubble susceptibility effect and characterized in vivo enhancements of microbubble susceptibility effects by entrapping iron oxide nanoparticles at 7 T, leading to the practical use of microbubbles as an intravascular MRI contrast agent.-
dc.languageengen_US
dc.relation.ispartofISMRM-ESMRMB Joint Annual Meeting-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.titleIn vivo demonstration of enhancing gas-filled microbubble magnetic susceptibility with iron oxide nanoparticlesen_US
dc.typeConference_Paperen_US
dc.identifier.emailChow, AMK: aprilcmk@hkusua.hku.hken_US
dc.identifier.emailChan, KWY: kannie@graduate.hku.hk-
dc.identifier.emailWu, EX: ewu@eee.hku.hk-
dc.description.naturepostprint-
dc.identifier.hkuros178203en_US

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