Conference Paper: Effects of hypercapnia on DTI quantitation

TitleEffects of hypercapnia on DTI quantitation
Authors
Issue Date2010
Citation
The ISMRM-ESMRMB Joint Annual Meeting 2010, Stockholm, Sweden, 1-7 May 2010. How to Cite?
AbstractThe accuracy of DTI derived parameters can directly affect the interpretation of underlying biological microstructures. However, the diffusivity measurements are likely to be confounded by the presence of vasculature. Nevertheless, little is known about to what degree blood signal from vasculature affects the diffusion quantitation. In this study, we examined the effects of hypercapnia on DTI quantification indices in anesthetized rat brains. It was found statistically significant changes occurred in all parametric DTI maps indicating that hemodynamic alterations can potentially affect the DTI indices and detection of tissue microstructures. Therefore, cautions must be taken when interpreting DTI parameters in vivo.
DescriptionPosters - Diffusion Perfusion: Animal Models: No. 4046
Persistent Identifierhttp://hdl.handle.net/10722/129675

 

DC FieldValueLanguage
dc.contributor.authorDing, AYen_US
dc.contributor.authorWu, EXen_US
dc.date.accessioned2010-12-23T08:40:55Z-
dc.date.available2010-12-23T08:40:55Z-
dc.date.issued2010en_US
dc.identifier.citationThe ISMRM-ESMRMB Joint Annual Meeting 2010, Stockholm, Sweden, 1-7 May 2010.en_US
dc.identifier.urihttp://hdl.handle.net/10722/129675-
dc.descriptionPosters - Diffusion Perfusion: Animal Models: No. 4046-
dc.description.abstractThe accuracy of DTI derived parameters can directly affect the interpretation of underlying biological microstructures. However, the diffusivity measurements are likely to be confounded by the presence of vasculature. Nevertheless, little is known about to what degree blood signal from vasculature affects the diffusion quantitation. In this study, we examined the effects of hypercapnia on DTI quantification indices in anesthetized rat brains. It was found statistically significant changes occurred in all parametric DTI maps indicating that hemodynamic alterations can potentially affect the DTI indices and detection of tissue microstructures. Therefore, cautions must be taken when interpreting DTI parameters in vivo.-
dc.languageengen_US
dc.relation.ispartofISMRM-ESMRMB Joint Annual Meeting-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.titleEffects of hypercapnia on DTI quantitationen_US
dc.typeConference_Paperen_US
dc.identifier.emailWu, EX: ewu@eee.hku.hken_US
dc.description.naturepostprint-
dc.identifier.hkuros178216en_US

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